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mouse homolog is a retinal proteoglycan and a major constituents of the interphotoreceptor matrix [RGD, Feb 2006].. De plus, nous expédions IMPG1 Anticorps (9) et IMPG1 Protéines (4) et beaucoup plus de produits pour cette protéine.
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The data from this study highlight that additional factors other than IMPG1 variation must play a role in drusen pathogensis in rhesus macaques.
IMPG1 and IMPG2 are new causal genes of vitelliform dystrophy, involved in 8% of our families.
IMPG1 mutations cause both autosomal-dominant and -recessive forms of vitelliform macular dystrophies.
A Leu579Pro mutation in the IMPG1 gene may play a causal role in benign concentric annular macular dystrophy (BCAMD).
Our results indicate that neither EEF1A1 nor IMPG1 could be responsible for RP25 in the studied families due to absence of any pathogenic variants.
The gene product of IMPG1 (designated IPM 150) is a member of a group of neuronal proteoglycans and/ or glycoproteins suspected to be essential in retinal adhesion and photoreceptor cell survival.
Murine orthologue of the human retinal glycoprotein IPM 150 (IMPG1), involved in retinal adhesion and photoreceptor cell survival. Analyses of IPM 150 and IPM 200 core proteins reveals the presence of multiple conserved domain of unknown function.
mouse homolog is a retinal proteoglycan and a major constituents of the interphotoreceptor matrix
interphotoreceptor matrix proteoglycan 1
, interphotoreceptor matrix proteoglycan of 150 kDa
, sialoprotein associated with cones and rods
, mucin-like glycoprotein associated with photoreceptor cells