anti-Intestinal Cell (MAK-Like) Kinase (ICK) Anticorps

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. De plus, nous expédions ICK Protéines (11) et ICK Kits (9) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ICK 22858 Q9UPZ9
ICK 56542 Q9JKV2
ICK 84411 Q62726
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Top anti-ICK Anticorps sur anticorps-enligne.fr

Showing 10 out of 89 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of ICK staining in HEK293T cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Immunohistochemical analysis of ICK staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the ant 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ICK Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using ICK Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from NIH-3T3 cells treated with starved 24h, using ICK (Phospho-Tyr159) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, treated with PBS 10uM 60', using ICK (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: ICK Antibody [NBP1-81459] - Staining of human cell line U-251MG shows positivity in vesicles. Immunohistochemistry-Paraffin: ICK Antibody [NBP1-81459] - Staining of human colon shows strong cytoplasmic positivity with a granular pattern in glandular cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p), WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$727.83
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, IHC (p) 100 μL Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cells, using ICK antibody. 100 μL Connectez-vous pour afficher 16 Days
$334.02
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails

ICK Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-ICK Anticorps mieux référencés

  1. Human Polyclonal ICK Primary Antibody pour ELISA, WB - ABIN564945 : Vallesi, Di Pretoro, Ballarini, Apone, Luporini et al.: A novel protein kinase from the ciliate Euplotes raikovi with close structural identity to the mammalian intestinal and male-germ cell kinases: characterization and functional implications in the ... dans Protist 2010 (PubMed)

  2. Human Polyclonal ICK Primary Antibody pour ICC, IF - ABIN4320963 : Häggarth, Hägglöf, Jaraj, Wester, Pontén, Ostman, Egevad: Diagnostic biomarkers of prostate cancer. dans Scandinavian journal of urology and nephrology 2011 (PubMed)

Plus d’anticorps contre ICK partenaires d’interaction

Human Intestinal Cell (MAK-Like) Kinase (ICK) interaction partners

  1. Our data provide evidence that heterozygous variants in ICK caused juvenile myoclonic epilepsy in 7% of the patients included in our analysis. Variant ICK affects cell processes that help explain microdysgenesis and polyspike networks observed on EEG in juvenile myoclonic epilepsy.

  2. These data identify ICK as an short rib polydactyly syndromes (SRPS)-associated gene and reveal that abnormalities in signalling pathways contribute to defective skeletogenesis

  3. findings suggest that increased ICK expression/activity in response to protein deprivation likely provides a novel protective mechanism to limit apoptosis and support compensatory mucosal growth under nutritional stress.

  4. the expressions of ICK/MAK (Montrer MAK Anticorps)/MOK (Montrer MOK Anticorps) proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  5. In glioblastoma cells with deregulated high levels of CCRK (Montrer CDK20 Anticorps), its depletion restores cilia through ICK and an ICK-related kinase MAK (Montrer MAK Anticorps), thereby inhibiting glioblastoma cell proliferation.

  6. High ICK expression is associated with prostate cancer.

  7. an important role for ICK in modulating the activity of mTORC1 through phosphorylation of Raptor (Montrer RPTOR Anticorps) Thr (Montrer TRH Anticorps)-908.

  8. ICK may play a role in the development of multiple organ systems. R272Q has been associated with endocrine-cerebro-osteodysplasia and may explain loss of function since the R272Q mutant fails to localize at the nucleus and has diminished kinase activity

  9. ICK plays an important role in the regulation of proliferation and differentiation of intestinal epithelial cells. ICK may control G1 cell cycle progression by regulating expression of cell cycle regulators cyclin D1 (Montrer CCND1 Anticorps), c-Myc (Montrer MYC Anticorps) and p21Cip1 (Montrer CDKN1A Anticorps).

  10. ICK and FBX9 (Montrer FBXO9 Anticorps) are divergently transcribed from a bidirectional promoter that is GC-rich (Montrer RELB Anticorps) and contains a CpG island.

Mouse (Murine) Intestinal Cell (MAK-Like) Kinase (ICK) interaction partners

  1. Data indicate an essential role for intestinal cell kinase (ICK) in lung development and advances the mechanistic understanding of endocrine-cerebro-osteodysplasia (ECO) syndrome.

  2. The results of this study found that loss of Ick leads to abnormal localization of the IFT component in kinocilia, PCP (Montrer BMP1 Anticorps) defects in HCs (Montrer HLCS Anticorps), and hearing dysfunction.

  3. findings suggest that increased ICK expression/activity in response to protein deprivation likely provides a novel protective mechanism to limit apoptosis and support compensatory mucosal growth under nutritional stress.

  4. the expressions of ICK/MAK (Montrer MAK Anticorps)/MOK proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  5. Data indicate that ciliary defects caused by a lack of functional intestinal cell kinase (ICK) leads to abnormal Sonic hedgehog (Shh (Montrer SHH Anticorps)) signaling, resulting in congenital disorders such as endocrine-cerebro-osteodysplasia (ECO) syndrome .

  6. ICK is a Kif3a (Montrer KIF3A Anticorps) kinase and essential for proper ciliogenesis in development by regulating ciliary transport at the tip of cilia.

  7. ICK and FBX9 (Montrer FBXO9 Anticorps) are divergently transcribed from a bidirectional promoter that is GC-rich (Montrer RELB Anticorps) and contains a CpG island.

ICK profil antigène

Profil protéine

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.

Gene names and symbols associated with ICK

  • intestinal cell kinase (ICK) anticorps
  • intestinal cell (MAK-like) kinase (ick) anticorps
  • intestinal cell kinase (ick) anticorps
  • intestinal cell kinase (Ick) anticorps
  • 2210420N10Rik anticorps
  • AI848300 anticorps
  • ECO anticorps
  • ICK anticorps
  • LCK2 anticorps
  • Mrk anticorps

Protein level used designations for ICK

intestinal cell (MAK-like) kinase , intestinal cell kinase , serine/threonine-protein kinase ICK-like , MAK-related kinase , hICK , laryngeal cancer kinase 2 , serine/threonine protein kinase , serine/threonine-protein kinase ICK , mICK , MRK , heart serine-threonine protein kinase

GENE ID SPECIES
421896 Gallus gallus
462772 Pan troglodytes
100014080 Monodelphis domestica
100056645 Equus caballus
100225015 Taeniopygia guttata
100401851 Callithrix jacchus
100451338 Pongo abelii
100498050 Xenopus (Silurana) tropicalis
100544019 Meleagris gallopavo
100552302 Anolis carolinensis
100582867 Nomascus leucogenys
22858 Homo sapiens
506286 Bos taurus
481843 Canis lupus familiaris
100511822 Sus scrofa
56542 Mus musculus
84411 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-ICK (ICK) Anticorps
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