anti-Junctophilin 3 (JPH3) Anticorps

Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. De plus, nous expédions Junctophilin 3 Protéines (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
JPH3 57338 Q8WXH2
JPH3 57340 Q9ET77
JPH3 307916  
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Top anti-Junctophilin 3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 76 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-JPH3 Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate WB Suggested Anti-JPH3 Antibody Titration:  1.0ug/ml  Positive Control:  Human Brain cell lysate 100 μL 2 to 3 Days
$289.00
Détails
Souris Lapin Inconjugué IHC (p), WB Western blot analysis of anti-Junctophilin 3 Pab (ABIN389172) in mouse brain tissue lysates (35 µg/lane). Junctophilin 3(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human brain tissue reacted with Junctophilin 3 Antibody (Center) (ABIN389172), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB 0.4 mL 6 to 8 Days
$484.00
Détails
Poulet Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-JPH3 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 0.05 mg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-JPH3 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 0.05 mg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB   0.1 mg 4 to 8 Days
$522.50
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB   0.1 mg 4 to 8 Days
$522.50
Détails
Humain Lapin Inconjugué IHC (p), ELISA, WB 50 μg 12 to 14 Days
$686.14
Détails
Humain Lapin Inconjugué IHC (p), ELISA, WB 50 μg 12 to 14 Days
$686.14
Détails

anti-Junctophilin 3 Anticorps mieux référencés

  1. Mouse (Murine) Polyclonal JPH3 Primary Antibody pour IHC (p), ELISA - ABIN543517 : Kakizawa, Kishimoto, Hashimoto, Miyazaki, Furutani, Shimizu, Fukaya, Nishi, Sakagami, Ikeda, Kondo, Kano, Watanabe, Iino, Takeshima: Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity. dans The EMBO journal 2007 (PubMed)
    Show all 3 Pubmed References

Plus d’anticorps contre Junctophilin 3 partenaires d’interaction

Human Junctophilin 3 (JPH3) interaction partners

  1. Thus, JPH3 was identified as a novel tumor suppressor gene methylated in colorectal and gastric tumors which promotes mitochondrial-mediated apoptosis, also as a potential metastasis and survival biomarker for digestive cancers.

  2. The expression of JPH isoforms was examined in human and mouse pancreatic tissues, and JPH3 expression was found in both the beta cells.

  3. This study identified that abnormal CTG expansions in JPH3 in patient with Huntington Disease.

  4. The present study aimed to characterize the genetic basis of the Huntington disease phenotype in South Africans and to investigate the possible origin of the JPH3 mutation.

  5. JPH3 mutations should be considered in the differential diagnosis of early-onset dementia and hypokinetic-rigid syndromes in individuals of African descent.

  6. The pathogenic mechanism of Huntington disease-like 2 is multifactorial, involving both a toxic gain of function of JPH3 RNA transcripts and a toxic loss of JPH3 expression in an experimental Huntington disease-like 2 mouse model.

  7. This study reveled the an antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice.

  8. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in the gene encoding junctophilin-3 in an HD patient who carried an allele with 50 uninterrupted repeats.

  9. This report on a South African family that presented with progressive dementia and a movement disorder affecting numerous family members. Genotyping of the JPH3 CTG repeat revealed pathogenic expansions in three affected individuals.

  10. 244 Patients with the diagnosis of Huntington's Disease and without mutation of the IT15 gene revealed one case of SCA17 but did not disclose the presence of two other diseases with a similar clinical manifestation: DRPLA and HDL2.

  11. HDL2 is caused by a pathological expansion of CAG/CTG triplets in exon 2A of the JPH3 gene.

  12. Data revealed that six polymorphisms of F10, PITRM1, PCSK2, JPH3, MYO7B, and AKAP12 were related (P<0.05) to the prevalence of chronic kidney disease.

Mouse (Murine) Junctophilin 3 (JPH3) interaction partners

  1. The expression of JPH isoforms was examined in human and mouse pancreatic tissues, and JPH3 expression was found in both the beta cells.

  2. Motor discoordination in mutant mice lacking junctophilin type 3

  3. Gene expression was slightly altered in the JP-3 and JP-4 Knockout cerebellum.

Junctophilin 3 (JPH3) profil antigène

Profil protéine

Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family. Alternatively spliced transcript variants have been described for this gene.

Gene names and symbols associated with anti-Junctophilin 3 (JPH3) Anticorps

  • junctophilin 3 (JPH3) anticorps
  • junctophilin 3 (Jph3) anticorps
  • junctophilin 3 (jph3) anticorps
  • CAGL237 anticorps
  • fc26e06 anticorps
  • HDL2 anticorps
  • JP-3 anticorps
  • Jp3 anticorps
  • si:ch211-255l14.9 anticorps
  • TNRC22 anticorps
  • wu:fc26e06 anticorps

Protein level used designations for anti-Junctophilin 3 (JPH3) Anticorps

junctophilin type 3 , junctophilin-3 , trinucleotide repeat containing 22 , junctophilin 3 , junctophilin-3-like

GENE ID SPECIES
57338 Homo sapiens
57340 Mus musculus
307916 Rattus norvegicus
415830 Gallus gallus
468063 Pan troglodytes
489669 Canis lupus familiaris
507713 Bos taurus
100018486 Monodelphis domestica
100411387 Callithrix jacchus
100445395 Pongo abelii
100512414 Sus scrofa
100730121 Cavia porcellus
569861 Danio rerio
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