KISS1 Receptor (KISS1R) Kits ELISA

The protein encoded by KISS1R is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. De plus, nous expédions KISS1R Anticorps (124) et KISS1R Protéines (6) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
KISS1R 84634 Q969F8
KISS1R 78976 Q924U1
KISS1R 114229 Q91V45
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Top KISS1R Kits ELISA sur anticorps-enligne.fr

Showing 3 out of 24 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.115 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
$736.84
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Souris 0.061 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$757.89
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Rat 0.059 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$800.00
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Plus Kits ELISA pour KISS1R partenaires d'interaction

Human KISS1 Receptor (KISS1R) interaction partners

  1. KISS1R signaling promotes drug resistance by increasing the expression of efflux drug transporter, breast cancer resistance protein (BCRP) and by inducing the activity and transcription of the receptor tyrosine kinase, AXL. BCRP and AXL transcripts are elevated in TNBC tumors, compared to normal breast.

  2. The positive association between kisspeptin levels in seminal plasma and semen quality supported an important role for the KISS1/GPR54 system in male reproductive health. Kisspeptin may be a potential marker of male reproductive health and an alternative strategy for treating infertility

  3. Three different Single Nucleotide Polymorphisms (SNPs) in familial central precocious puberty were detected in GPR54: rs10407968 (24A > T) in 13 subjects (52%); rs3050132 (1091 T > A) in 16 subjects (64%), and a novel polymorphism (492C > G) in one subject (4%), while three subjects (12%) had no SNPs. No mutations were found in the GPR54 gene.

  4. KISS1 expression is decreased during carcinogenesis in gastric mucosa. More advanced tumors and more aggressive histological types produce lower KISS1 levels. In addition, no KISS1R is produced in malignant gastric epithelium, while KISS1R is only weakly expressed in normal gastric epithelium.

  5. The study shows that KISS1R mutants are responsible for the normosmic congenital hypogonadotrophic hypogonadism phenotype in only a small minority of cases

  6. Kisspeptin-10 may contribute to accelerate the progression and instability of atheromatous plaques, leading to plaque rupture. The GPR54 antagonist may be useful for prevention and treatment of atherosclerosis.

  7. The missense variant (c.1091Tgt;A) was a nonsynonymous polymorphism that induces amino acid substitution of p.Leu364His. The haplotype CAGTGTC was detected more frequently in the central precocious puberty group.

  8. Metabolism and Energy Expenditure, But Not Feeding or Glucose Tolerance, Are Impaired in Young Kiss1r KO Female Mice

  9. Neuropeptide derivatives to regulate the reproductive axis: Kisspeptin receptor (KISS1R) ligands and neurokinin-3 receptor (NK3R) ligands.

  10. In human cumulus GCs, kiss1r mRNA levels were positively correlated with age but not with BMI. There was no expression of kiss1 mRNA in either cumulus or mural GCs

  11. KISS1R signaling induces invadopodia formation and activation of key invadopodia proteins, cortactin, cofilin and membrane type I matrix metalloproteases (MT1-MMP).

  12. KISS1R Low Expression Correlates with Colorectal Liver Metastasis.

  13. KiSS1 is a metastasis suppressor gene of pancreatic cancer, and this suppression is not dependent on the expression levels of GPR54.

  14. confirmed that mutations in KISS1 and KISS1R are not a common cause for ICPP

  15. Effects of systematic N-terminus deletions and benzoylations of endogenous RF-amide peptides on NPFF1R, NPFF2R, GPR10, GPR54 and GPR103.

  16. Two novel heterozygous missense mutations in FGFR1 and one novel heterozygous missense mutation in KISS1R, were identified in in Chinese Kallmann Syndrome Males with Cleft Lip/Palate.

  17. The majority of human non-functioning pituitary tumors expressed KISS1R with lower rates of expression in other types of pituitary tumors.

  18. The promoter of GPR54 is unmethylated in normal endometrium

  19. Present data do not confirm the protective role of KiSS1/KiSS1R in breast cancer progression, but our results do support the hypothesis that KiSS1/KiSS1R system is activated even in primary breast cancer and sustained during invasion to local lymph nodes.

  20. Normosmic idiopathic hypogonadotropic hypogonadism due to a novel homozygous nonsense c.C969A (p.Y323X) mutation in the KISS1R gene in three unrelated families.

Mouse (Murine) KISS1 Receptor (KISS1R) interaction partners

  1. we demonstrate that in the presence of E2, NKB signaling induces LH release in a kisspeptin-independent manner through the activation of NK3R (NKB receptor) neurons in the posterodorsal medial amygdala (MePD). Importantly, we show that chemogenetic activation of MePD Kiss1 neurons induces LH release, however, the stimulatory action of NKB in this area is Kiss1 neuron-independent.

  2. These lines of evidence suggest that downregulation of Ob-R and kisspeptin/GPR54 in the murine hypothalamus may contribute to male hypogonadism caused by high-fat diet-induced obesity.

  3. G-protein coupled receptor 54 (GPR54) deficiency leads to elevated experimental autoimmune encephalomyelitis (EAE) disease severity independent of the reproductive axis. GPR54 deficiency leads to impaired immunotolerance in association with reduced number of Regulatory T-Lymphocytes, increased T-cell activation, and altered thymocyte subsets.

  4. while uterine growth was fully rescued by E2 treatment of Kiss1(-/-) mice and by genetic restoration of kisspeptin signaling in GnRH neurons in Kiss1r(-/-) mice, functional adenogenesis was only marginally restored. Thus, while uterine growth is largely dependent on ovarian E2-output via central kisspeptin signaling, peripheral kisspeptin signaling is indispensable for endometrial adenogenesis and function

  5. Study found unaltered hypothalamic metabolic gene expression in Kiss1 receptor knockout mice despite obesity and reduced energy expenditure.

  6. Nesfatin-1 increased Kiss1R expression in hypothalamic cells.

  7. Kisspeptin-10 may contribute to accelerate the progression and instability of atheromatous plaques, leading to plaque rupture. The GPR54 antagonist may be useful for prevention and treatment of atherosclerosis.

  8. data suggest the utility of the KISS1R as a novel biomarker for multiple myeloma, capable of targeting both tumor cells and host cells of the tumor microenvironment

  9. kiss1 and kiss1r mRNA levels were significantly higher in old compared to reproductive-aged mice, and diet-induced obesity did not alter kiss1 or kiss1r mRNA levels. Compared to young control mice, young MCP-1 knockout mice had significantly lower ovarian kiss1 mRNA

  10. On D4 of pregnancy, the mouse uterus expresses a functional kisspeptin/KISS1R signaling system.

  11. Gnaq was selectively inactivated in GnRH neurons of global Gna11--null mice, but they still responded to kisspeptin, confirming that KISS1R signals via non-Galphaq/11-coupled pathways.

  12. orchestrated onset of kisspeptin and GPR54 expression in the male embryonic brain at embryonic day 13.5

  13. Results demonstrate defective negative feedback in global Gpr54-null mice that cannot be attributed to a lack of prior exposure of the gonadotropin-releasing hormone neuronal network to cyclical estradiol

  14. Expression of Kiss1 and Gpr54 was confirmed in mouse placenta but no differences in birth weight were found in mice that had been supported by a mutant placenta during fetal development.

  15. Kiss1/GPR54 system is involved in promoting uterine decidualization during early pregnancy in mice

  16. Kiss1r in GnRH neurons is critical for reproductive development and fertility.

  17. kisspeptin-1 and Kiss1r signaling influences BW, energy expenditure, and glucose homeostasis in a sexually dimorphic and partially sex steroid-independent manner

  18. kisspeptin receptor (Kiss1r), a GPCR that is activated by kisspeptin to regulate the onset of puberty and adult reproductive function, is enriched in cilia projecting from mouse

  19. Oocytes fail to respond to gonadotropins with increased trk-B tyrosine kinase (Ntrk)2 expression in the absence of KISS1R

  20. Failure of follicular development and ovulation linked to the absence of Kiss1r cannot be fully rescued by (even extended) gonadotropin replacement.

Zebrafish KISS1 Receptor (KISS1R) interaction partners

  1. not absolutely required for zebrafish reproduction

  2. duplicated kiss1r genes evolved a distinct gene expression pattern, different ligand selectivity, and novel nuclear isoforms. While a single kiss1ra mRNA was detected exclusively in the brain, 5 kiss1rb transcripts were found in many peripheral tissues.

  3. The only site of expression of kiss1r mRNA cells was the ventromedial habenula, showing an expression pattern very similar to that of the kiss1 mRNA or proKiss1 peptide.

  4. Zebrafish kiss1r was expressed predominantly in the brain, with a minor level of expression in the eye.

  5. Kiss1/Kiss1r system may participate in puberty initiation in fish as well.

Pig (Porcine) KISS1 Receptor (KISS1R) interaction partners

  1. The KISS1R gene is mapped and mutations within the gene are determined not to be responsible for divergent age at puberty.

Cow (Bovine) KISS1 Receptor (KISS1R) interaction partners

  1. The metabolism of kisspeptin 10 [Kp-10] and kisspeptin-1 receptor [Kiss-1R] in epithelial cells isolated from bovine placentas at the first trimester are reported.[Kp-10; Kiss-1R]

Goat KISS1 Receptor (KISS1R) interaction partners

  1. Data suggest that activation of GPR54 is involved in regulation of pulsatile and surge mode secretion of luteinizing hormone from hypothalamus.

KISS1R profil antigène

Antigen Summary

The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.

Gene names and symbols associated with KISS1 Receptor (KISS1R) Kits ELISA

  • KISS1 receptor (KISS1R) anticorps
  • KISS1 receptor (Kiss1r) anticorps
  • KISS1 receptor a (kiss1ra) anticorps
  • KISS1 receptor (kiss1r) anticorps
  • axor12 anticorps
  • CPPB1 anticorps
  • gpr54 anticorps
  • gpr54-1 anticorps
  • gpr54a anticorps
  • HH8 anticorps
  • HOT7T175 anticorps
  • KiSS-1 anticorps
  • KISS-1R anticorps
  • kiss1r anticorps
  • kiss1rl anticorps
  • kissr1a anticorps
  • kissr2 anticorps
  • si:dkey-31m5.9 anticorps

Protein level used designations for KISS1 Receptor (KISS1R) Kits ELISA

G protein-coupled receptor 54 , G-protein coupled receptor OT7T175 , hypogonadotropin-1 , kiSS-1 receptor , kisspeptins receptor , metastin receptor , G-protein coupled receptor 54 , kiSS-1R , orphan G protein-coupled receptor GPR54 , rOT7T175 , mOT7T175 , orphan G protein-coupled receptor 54 , KISS1 receptor like , kisspeptin receptor 2 , KiSS-1 receptor

GENE ID SPECIES
84634 Homo sapiens
78976 Rattus norvegicus
114229 Mus musculus
561898 Danio rerio
733704 Sus scrofa
100316929 Xenopus (Silurana) tropicalis
612374 Canis lupus familiaris
528699 Bos taurus
106502331 Capra hircus
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