anti-Kell Blood Group, Metallo-Endopeptidase (KEL) Anticorps

KEL encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. De plus, nous expédions KEL Protéines (13) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
KEL 23925 Q9EQF2
KEL 3792 P23276
KEL    
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Top anti-KEL Anticorps sur anticorps-enligne.fr

Showing 10 out of 57 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EIA, FACS, WB Flow cytometric analysis of K562 cells using CD238 / KEL Antibody (Center) Cat.-No AP52330PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of CD238 / KEL Antibody (Center) in K562 cell line lysates (35ug/lane). This demonstrates the KEL antibody detected the KEL protein (arrow). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué IHC, WB Immunohistochemical analysis of CD238 staining in human spleen formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the Western blot analysis of CD238 expression in mouse heart (A) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, WB   100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Humain Lapin Inconjugué FACS, WB Western blot analysis in K562 cell line lysates (35ug/lane). Flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cells, using KEL antibody. 100 μL Connectez-vous pour afficher 16 Days
$366.77
Détails
Souris Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Mouse Spleen lysate; Primary Ab: 1µg/ml Rabbit Anti-Mouse KEL Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Western Blot; Sample: Mouse Testis lysate; Primary Ab: 1µg/ml Rabbit Anti-Mouse KEL Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Connectez-vous pour afficher 15 to 18 Days
$342.00
Détails
Humain Lapin Inconjugué IHC (p) Immunochemical staining of human KEL in human spleen with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Connectez-vous pour afficher 14 to 16 Days
$218.90
Détails
Humain Souris Inconjugué AGG, EIA, H, IHC (fro)   0.2 mg Connectez-vous pour afficher 6 to 8 Days
$478.50
Détails
Souris Lapin Inconjugué IF/ICC, IHC, IP, WB Western blot analysis of Mouse Spleen lysate, using Mouse KEL Antibody (1 µg/ml) and HRP-conjugated Goat Anti-Rabbit antibody ( Western blot analysis of Mouse Testis lysate, using Rabbit Anti-Mouse KEL Antibody (1 µg/ml) and HRP-conjugated Goat Anti-Rabbit antibody (abx400043, 0.2 µg/ml). 100 μg Connectez-vous pour afficher 11 to 18 Days
$426.40
Détails

Plus d’anticorps contre KEL partenaires d’interaction

Mouse (Murine) Kell Blood Group, Metallo-Endopeptidase (KEL) interaction partners

  1. B cells require signaling from IFN-alpha/beta to produce alloantibodies to the human KEL glycoprotein in mice

  2. Absence of Kell was accompanied by changes in erythrocyte K(+), Mg(2+), Na(+) & Ca(2+) transport associated with changes in mean cellular volume & corpuscular hemoglobin concentration mean. Kel loss increased Mg(2+) permeability.

  3. The targeted disruption of Kel in mouse enabled us to identify phenotypes that would not be easily detected in humans lacking Kell glycoprotein.

Human Kell Blood Group, Metallo-Endopeptidase (KEL) interaction partners

  1. Ten new silent KEL alleles were identified in Japanese individuals with the Ko phenotype.

  2. description of four new KEL*01M alleles

  3. The expression of Kell glycoprotein on RBCs is not critical to the erythrocyte function

  4. Through molecular genotyping we also identified polymorphisms in RhCE, Kell, Duffy, Colton, Lutheran and Scianna loci in donors and patients.

  5. A relatively increased KEL1 antigen expression in KEL:1,2null and KEL:1,2mod individuals suggest that the expression of Kell-XK complexes depends on the availability of the XK protein.

  6. High-throughput Kell, Kidd, and Duffy matrix-assisted laser desorption/ionization, time-of-flight mass spectrometry-based blood group genotyping of 4000 donors shows close to full concordance with serotyping and detects new alleles.

  7. After sequencing the whole KEL gene, we found three new missense mutations: c.455A>G (p.Tyr152Cys) at Exon 5, c.2111A>C (p.Pro704His) at Exon 19, and c.1726G>C (p.Gly576Arg) at Exon 16.

  8. A new allele, KEL(Thr193Met, Pro326Leu), has a drastic effect on the Kell glycoprotein probably due to defects in protein trafficking or reduced membrane integration.

  9. Sequence analysis of genomic DNA from 2 Caucasian Brazilian women revealed a new homozygous change in KEL Exon 2, a guanine to an adenine substitution at Position 71 (c.71G>A, NCBI_ss#: 831878329) leading to a premature stop codon.

  10. A compensatory mechanism of the KELmod allele deficient expression in heterozygote patients may exist. Retrospective analysis of 80,000 subjects showed a local KEL:1,-2 frequency 4 times lower than expected.

  11. A rare allele in this family has been numbered KEL*02M.04 and contains a Gly703Arg substitution that appears to cause weakened expression of Kell antigens and a Kmod phenotype when in trans with a null allele in the propositus.

  12. Systematic DNA analysis showed that the number of discordant phenotype/genotype results, related to silent KEL*02 alleles was higher than expected in France.

  13. These findings identify the translational start site and define the full cytoplasmic tail of the human Kell glycoprotein.

  14. Novel IVS6-13C>T mutation recognized as a cause of discrepancy between phenotyping and genotyping in KEL*3,4 polymorphism identification.

  15. x-ray analysis of Kell blood group protein

  16. Kell K2 antigen is a catalytically active metalloprotease, but the rare Kell K1 antigen is inactive

  17. KEL6 red blood cells have endothelin-3-converting enzyme activity

  18. Results demonstrate the lack of Kell expression in rodent neuronal cells and strongly suggest the same for human cerebral tissue, in which the Kellprotein was exclusively observed on RBCs in cerebral blood vessels.

  19. This is the first description of the KEL*1,3 allele encoding KEL1 and KEL3 on the same molecule.

  20. In screening 87665 unrelated healthy blood donors in China, two K(0) probands were detected; in exon 3, 185insT (Ser62Phe and a premature stop codon in exon 4

KEL profil antigène

Profil protéine

This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.

Gene names and symbols associated with KEL

  • Kell blood group (Kel) anticorps
  • Kell blood group, metallo-endopeptidase (KEL) anticorps
  • CD238 anticorps
  • ECE3 anticorps

Protein level used designations for KEL

Kel blood group protein , Kell blood group, metallo-endopeptidase , Kell protein , kell blood group glycoprotein homolog , kell blood group antigen , kell blood group glycoprotein

GENE ID SPECIES
23925 Mus musculus
3792 Homo sapiens
Fournisseurs de qualité sélectionnés pour anti-KEL (KEL) Anticorps
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