anti-Keratin 8 (KRT8) Anticorps

KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. De plus, nous expédions Keratin 8 Protéines (44) et Keratin 8 Kits (20) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
KRT8 3856 P05787
KRT8 16691 P11679
KRT8 25626 Q10758
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Top anti-Keratin 8 Anticorps sur anticorps-enligne.fr

Showing 10 out of 983 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-KRT8 Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate KRT8 is supported by BioGPS gene expression data to be expressed in HepG2 Immunohistochemistry with Small intestine tissue at an antibody concentration of 5µg/ml using anti-KRT8 antibody (ARP42029_P050) 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-KRT8 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate Rabbit Anti-KRT8 Antibody  Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of Cytokeratin 8 using anti- Cytokeratin 8 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat liver tissue lysates,   Lane 2: mouse ovary tissue lysates,   Lane 3: mouse liver tissue lysates,   Lane 4: MCF-7 whole cell lysates,  Lane 5: A549 whole cell lysates,  Lane 6: HELA whole Cell lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti- Cytokeratin 8 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for Cytokeratin 8 at approximately 54KD, 56KD. The expected band size for Cytokeratin 8 is at 54KD. IHC analysis of Cytokeratin 8 using anti- Cytokeratin 8 antibody . Cytokeratin 8 was detected in paraffin-embedded section of mouse liver tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti- Cytokeratin 8 Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Humain Souris Inconjugué FACS, IHC (fro), IF, IHC (p), WB   0.1 mg Connectez-vous pour afficher 6 to 8 Days
$412.50
Détails
Humain Souris Inconjugué ELISA, ICC, IHC, WB Figure 1: Western blot analysis using CK8 mouse mAb against A549 (1), Hela (2), MCF-7 (3), A431 (4) and HepG2 (5) cell lysate. Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma (A), lung cancer (B) and ovarian cancer tissue (C), showing membrane and cytoplasmic localization with DAB staining using CK8 mouse mAb. Dilution: 1/200 - 1/1000 100 μL Connectez-vous pour afficher 10 to 11 Days
$561.00
Détails
Humain Lapin Inconjugué ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Kidney, antibody was diluted at 1:100. 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Humain Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of Cytokeratin 8 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytokeratin 8 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of Cytokeratin 8 staining in DLD cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytokeratin 8 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Boeuf (Vache) Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of Cytokeratin 8 staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytokeratin 8 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of Cytokeratin 8 (pS73) expression in HeLa (A), NIH3T3 (B), H9C2 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$575.00
Détails

anti-Keratin 8 Anticorps mieux référencés

  1. Human Monoclonal KRT8 Primary Antibody pour ICC, FACS - ABIN335327 : Ivanyi, Groeneveld, Van Doornewaard, Mooi, Hageman: Keratin subtypes in carcinomas of the uterine cervix: implications for histogenesis and differential diagnosis. dans Cancer research 1990 (PubMed)
    Show all 10 Pubmed References

  2. Hamster Monoclonal KRT8 Primary Antibody pour IHC (fro), IHC (p) - ABIN920532 : Moll, Franke, Schiller, Geiger, Krepler: The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. dans Cell 1983 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal KRT8 Primary Antibody pour ICC, IHC (fro) - ABIN920530 : Troyanovsky, Guelstein, Tchipysheva, Krutovskikh, Bannikov: Patterns of expression of keratin 17 in human epithelia: dependency on cell position. dans Journal of cell science 1990 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal KRT8 Primary Antibody pour IF (cc), IF (p) - ABIN737751 : Zhang, Li, Fu, Li: Calcitonin is expressed in the submaxillary glands of rats. dans Bosnian journal of basic medical sciences / Udruženje basi?nih mediciniskih znanosti = Association of Basic Medical Sciences 2014 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal KRT8 Primary Antibody pour IHC (fro), IHC (p) - ABIN284054 : Fernandez-Valdivia, Mukherjee, Ying, Li, Paquet, DeMayo, Lydon: The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse. dans Developmental biology 2009 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal KRT8 Primary Antibody pour IHC (fro), IHC (p) - ABIN284055 : Bardag-Gorce, Oliva, Li, French, French: SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model. dans Experimental and molecular pathology 2010 (PubMed)
    Show all 2 Pubmed References

  7. Chicken Monoclonal KRT8 Primary Antibody pour IHC (fro), IHC (p) - ABIN268153 : Rossdeutscher, Li, Luco, Fadhil, Ochietti, Camirand, Huang, Reinhardt, Muller, Kremer: Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer. dans Cancer prevention research (Philadelphia, Pa.) 2015 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal KRT8 Primary Antibody pour IF, IHC - ABIN965965 : Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast. dans Cancer genetics and cytogenetics 2007 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal KRT8 Primary Antibody pour IF (cc), IF (p) - ABIN737758 : Jayachandran, Lugo, Heiling, Miller, Rule, Lieske: Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study. dans Biology of sex differences 2015 (PubMed)

  10. Cow (Bovine) Monoclonal KRT8 Primary Antibody pour IF, IHC (p) - ABIN120663 : Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology. dans The Journal of pathology 1991 (PubMed)

Plus d’anticorps contre Keratin 8 partenaires d’interaction

Human Keratin 8 (KRT8) interaction partners

  1. Cytokeratin 5 (Montrer KRT5 Anticorps)/6 and CK8/18 immunohistochemistry on 150 cases of triple negative breast cancers was performed and association with various clinicopathological features was evaluated.

  2. KRT8 mRNA and protein are upregulated in anaplastic thyroid carcinoma. KRT8 protein binds to annexin A2 (Montrer ANXA2 Anticorps).

  3. K8/K18 (Montrer KRT18 Anticorps) variants are overrepresented in Chinese NAFLD (Montrer TSC2 Anticorps) patients and might accelerate liver fat storage through insulin (Montrer INS Anticorps) resistance.

  4. regulated enhancement of autophagy with concurrent increased expression of KRT8 and the inhibition of KRT8 phosphorylation serve to inhibit oxidative stress-induced (Montrer SQSTM1 Anticorps) epithelial-mesenchymal transitionof retinal pigment epithelium cells.

  5. Histopathological differences between Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU)-ablated tissue and radiofrequency (RF)-ablated tissue were demonstrated. CK-8 was more reliable for cell viability assessment than H&E when used directly after ablation

  6. Loss of activating transcription factor 3 (ATF3 (Montrer ATF3 Anticorps)) in knockout mice promotes the emergence of keratins CK5 (Montrer KRT5 Anticorps)+CK8+ epithelial cells.

  7. Data show that the filament elongation of both desmin (Montrer DES Anticorps) and keratin K8/K18 (Montrer KRT18 Anticorps) proceeds very similar to that of vimentin (Montrer VIM Anticorps).

  8. New insights into interactions between the nucleotide-binding domain of CFTR (Montrer CFTR Anticorps) and keratin 8.

  9. We present results of a multicentre study measuring UBC (Montrer RPS27A Anticorps)((R)) Rapid Test(test that detects fragments of cytokeratins 8 and 18 in urine) in bladder cancer patients and healthy controls with focus on carcinoma in situ (CIS (Montrer CISH Anticorps)) and high-grade bladder cancer.

  10. Data show that after siRNA transfection, TGF-beta1 (Montrer TGFB1 Anticorps) protein level was decreased, and CK18 (Montrer KRT18 Anticorps) proteins was decreased, while CK8 proteins was increased, and TERT (Montrer TERT Anticorps) protein expression was slightly increased at 96 h.

Mouse (Murine) Keratin 8 (KRT8) interaction partners

  1. The authors found that keratin 8 suppressed toll (Montrer TLR4 Anticorps)-like receptor-induced nuclear factor (NF)-kappaB (Montrer NFKB1 Anticorps) activation and interacted with the adaptor tumor necrosis factor (TNF (Montrer TNF Anticorps)) receptor-associated factor 6 (TRAF6 (Montrer TRAF6 Anticorps)) to prevent its polyubiquitination.

  2. K8/K18 (Montrer KRT18 Anticorps) interact with Notch1 (Montrer NOTCH1 Anticorps) and regulate Notch1 (Montrer NOTCH1 Anticorps) signalling activity during differentiation of the colonic epithelium.

  3. Mitochondria in K8 wild-type beta cells and MIN6 insulinoma cells overexpressing K8 and 18 are more stationary compared with mitochondria in keratin-deficient cells

  4. K8/K18 (Montrer KRT18 Anticorps)-dependent PKCdelta (Montrer PKCd Anticorps)- and ASMase (Montrer SMPD1 Anticorps)-mediated modulation of lipid raft size can explain the more prominent FasR-mediated signaling resulting from K8/K18 (Montrer KRT18 Anticorps) loss.

  5. DRA mRNA levels were decreased by three- to fourfold and DRA protein was almost entirely lost in K8-/- cecum and proximal and distal colon compared with K8+/+.

  6. Upregulation of IL-22 (Montrer IL22 Anticorps) in combination with a complete loss of its negative regulator IL-22BP (Montrer IL22RA2 Anticorps), and increased downstream STAT3 (Montrer STAT3 Anticorps)-signaling in K8(-/-) and K8(-/-)Apc (Montrer APC Anticorps)(Min/+) colonic epithelia confirmed that the IL-22 (Montrer IL22 Anticorps) pathway, important in inflammation, proliferation and tissue regeneration

  7. Krt8 deletion (Krt8(-/-)) in a mouse model of cystic fibrosis (Montrer S100A8 Anticorps) (F508del-Cftr (Montrer CFTR Anticorps) mice) increased the levels of circulating markers of bone formation, corrected the expression of osteoblast phenotypic genes, promoted trabecular bone formation and improved bone mass and microarchitecture. Krt8 deletion corrected overactive NF-kappaB (Montrer NFKB1 Anticorps) signaling & decreased Wnt (Montrer WNT2 Anticorps)-beta-catenin (Montrer CTNNB1 Anticorps) signaling induced by F508del-Cftr (Montrer CFTR Anticorps) mutation in osteoblasts.

  8. Autoantibodies to several antigens were identified in 81% of K8-null male mice 8 mo or older. Similar autoantibodies were detected in aging K18 (Montrer KRT18 Anticorps)-null male mice that had a related liver phenotype but normal colon compared with K8-null mice

  9. The regulation of the SCFA-MCT1 (Montrer MCTS1 Anticorps)-HMGCS2 (Montrer HMGCS2 Anticorps) axis is disrupted in K8(-/-) colonocytes, suggesting a role for keratins in colonocyte energy metabolism and homeostasis.

  10. In several liver stress models epiplakin and K8 genes displayed identical expression patterns and transgenic K8 overexpression resulted in elevated hepatic epiplakin levels.

Cow (Bovine) Keratin 8 (KRT8) interaction partners

  1. Results did not support that K8/K18 (Montrer KRT18 Anticorps) filaments influence the expression of Fas (Montrer FAS Anticorps) on the surface of luteal cells.

Zebrafish Keratin 8 (KRT8) interaction partners

  1. Data identify Danio rerio keratins 8/18 as the true orthologs of the human keratin pair 8/18.

Pig (Porcine) Keratin 8 (KRT8) interaction partners

  1. This study reveals clear genetic-statistical evidence for a link of KRT8, FAF1 (Montrer FAF1 Anticorps) and PTH1R (Montrer PTH1R Anticorps) with some of leg weakness related traits in pigs.

  2. Mechanical injury of vascular smooth muscle up-regulated keratin 8.

Keratin 8 (KRT8) profil antigène

Profil protéine

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with anti-Keratin 8 (KRT8) Anticorps

  • keratin 8 (KRT8) anticorps
  • keratin 8 (Krt8) anticorps
  • keratin 8 S homeolog (krt8.S) anticorps
  • keratin 8 (krt8) anticorps
  • AA960620 anticorps
  • AL022697 anticorps
  • AU019895 anticorps
  • card2 anticorps
  • cb186 anticorps
  • CK-8 anticorps
  • ck8 anticorps
  • cyk8 anticorps
  • CYKER anticorps
  • DKFZp468F2127 anticorps
  • DreK8 anticorps
  • EndoA anticorps
  • k2c8 anticorps
  • K8 anticorps
  • KERATIN8 anticorps
  • KO anticorps
  • Krt-2.8 anticorps
  • krt2-5 anticorps
  • krt2-8 anticorps
  • KRT8 anticorps
  • MGC69490 anticorps
  • sb:cb186 anticorps
  • wu:fa20h05 anticorps
  • wu:fa95h10 anticorps
  • wu:fb96c06 anticorps
  • zf-K8 anticorps
  • zfk8 anticorps

Protein level used designations for anti-Keratin 8 (KRT8) Anticorps

cytokeratin 8 , cytokeratin-8 , keratin, type II cytoskeletal 8 , type-II keratin Kb8 , CK-8 , cytokeratin endo A , keratin complex 2, basic, gene 8 , keratin-8 , K8 , KERA , cytokeratin-A , keratin 8 , keratin complex 2, basic, gene 5 , etID33550.23 , etID43142.23 , etID43142.8 , keratin, type 2, gene 8

GENE ID SPECIES
3856 Homo sapiens
16691 Mus musculus
25626 Rattus norvegicus
281269 Bos taurus
380217 Xenopus laevis
426896 Gallus gallus
431676 Xenopus (Silurana) tropicalis
486513 Canis lupus familiaris
700449 Macaca mulatta
737628 Pan troglodytes
797433 Danio rerio
100152077 Sus scrofa
100174430 Pongo abelii
101110495 Ovis aries
100348891 Oryctolagus cuniculus
100736243 Cavia porcellus
Fournisseurs de qualité sélectionnés pour anti-Keratin 8 (KRT8) Anticorps
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