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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Gene names and symbols associated with KLRC1

• killer cell lectin like receptor C1 (Klrc1) anticorps
• killer cell lectin like receptor C1 (KLRC1) anticorps
• NKG2-A/NKG2-B type II integral membrane protein-like (NKG2A) anticorps
• killer cell lectin-like receptor subfamily C, member 3 (KLRC3) anticorps
• killer cell lectin-like receptor subfamily C, member 1 (KLRC1) anticorps
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• killer cell lectin-like receptor subfamily C, member 1 (Klrc1) anticorps

• CD159a anticorps
• KLRC1 anticorps
• NKG2 anticorps
• NKG2-A anticorps
• NKG2A anticorps
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• NKG2B anticorps
• rNKG2A anticorps

Protein level used designations for KLRC1

natural killer cell protein group 2-A (NKG2A) , CD159 antigen-like family member A , NK cell receptor A , NKG2-A/B-activating NK receptor , NKG2-A/NKG2-B type II integral membrane protein , killer cell lectin-like receptor subfamily C, member 1 , C-lectin type II protein , NKG2-1/B activating NK receptor , NKG2-A/B type II integral membrane protein , natural killer cell lectin , natural killer group protein 2