Killer Cell Lectin-Like Receptor Subfamily D, Member 1 Protéines (KLRD1)

Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. De plus, nous expédions Killer Cell Lectin-Like Receptor Subfamily D, Member 1 Anticorps (263) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
KLRD1 3824 Q13241
KLRD1 16643 O54707
KLRD1 25110 O35778
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Top Killer Cell Lectin-Like Receptor Subfamily D, Member 1 Protéines sur anticorps-enligne.fr

Showing 10 out of 19 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,262.31
Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,749.58
Détails
Escherichia coli (E. coli) Humain His tag,T7 tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$880.00
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails
Baculovirus infected Insect Cells Humain His tag 50 μg Connectez-vous pour afficher 13 to 16 Days
$1,230.77
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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Human Cells Humain His tag   10 μg Connectez-vous pour afficher 15 to 16 Days
$250.00
Détails
Levure Pongo pygmaeus His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,324.67
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Levure Chien His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,324.67
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,324.67
Détails

KLRD1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , , , ,
, , , ,
Mouse (Murine)
,
Rat (Rattus)

Plus protéines pour Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) partenaires d'interaction

Human Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) interaction partners

  1. an early response by KLRD1-expressing Natural killer cells may control influenza infection.

  2. Collectively, these results provide evidence for the first time that CD94/NKG2C is involved in chronic graft-versus-host disease prevention

  3. CD94 and NKG2A polymorphisms may contribute to genetic susceptibility to rheumatoid arthritis or affect the response to anti-TNF therapy in patients of Caucasian origin.

  4. Coengagement of inhibitory receptors, either KIR2DL1 or CD94-NKG2A, did not inhibit phosphorylation of Stat5 but inhibited selectively phosphorylation of Akt and S6 ribosomal protein.

  5. it is not clear if high expression of CD94 on peripheral blood NK cells is related to abnormal activity of endometrial NK cells.

  6. Data indicate that NKG2 receptor NKG2E was capable of associating with CD94 and DAP12 but that the complex was retained intracellularly at the endoplasmic reticulum.

  7. Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

  8. Data indicate that the expression of KLRD1 (CD94) and NKG2E (KLRC3) was reduced in NK-enriched cells in fulminant type 1 diabetes.

  9. NKG2C zygosity influences CD94/NKG2C receptor function and the NK-cell compartment redistribution in response to human cytomegalovirus.

  10. Synergistic inhibition of natural killer cells by the nonsignaling molecule CD94.

  11. Studies indicate that HLA-E interacts with CD94/NKG2 receptors expressed mainly on the surface of natural killer (NK) cells, thus confining its role to the regulation of NK-cell function.

  12. Results suggested that the low expression level of CD94/NKG2A upon gammadelta T cell activation might lead to the over-activation of gammadelta T cells in patients with SLE.

  13. Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A

  14. Loss of CD94 is associated with rheumatoid arthritis.

  15. These results suggested that these glycans can interact with NKG2D and CD94 to modulate NK cell-dependent cytotoxicity.

  16. The differences of CD94 and NKG2 expression between nasal NK/T-cell lymphomas and B cell lymphoma or T cell lymphoma were statistically significant.

  17. increased expression on natural killer cells in women with recurrent spontaneous abortion after IVIG therapy

  18. CD94/NKG2C might be involved in triggering cytotoxic lymphocytes in patients with Toxic epidermal necrolysis and Stevens-Johnson syndrome

  19. human CD56(bright) NK cells progress through a continuum of differentiation that ends with a CD94(low)CD56(dim) phenotype.

  20. demonstrate that human cytomegalovirus induces an immediate proportional enlargement of a functionally active CD94/NKG2A expressing subset of natural killer cells.

Cow (Bovine) Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) interaction partners

  1. These findings suggest that the CD94/NKG2A heterodimers in cattle, in contrast to other species, are binding several different ligands.

Mouse (Murine) Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) interaction partners

  1. Segregation of a spontaneous Klrd1 mutation in DBA/2 mouse substrains

  2. The transmembrane region sequences of CD94 and NKG2 in mouse and rat differ markedly from other mammalian orthologs by the presence of a lysine residue in the transmembrane region.

  3. The complex interplay between various stimuli may account for the variable expression of CD94/NKG2A during responses to different pathogens in vivo.

  4. expression of CD94 and its associated NKG2A, NKG2C, and NKG2E subunits is dispensable for NK cell development, education, and many NK cell functions

  5. show that CD94, a molecule preferentially expressed by NK cells, is essential for the resistance of C57BL/6 mice to mousepox, a disease caused by the Orthopoxvirus ectromelia virus

  6. Implications of CD94 deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation.

  7. CD94 and NKG2 were both expressed early in NK cell development, sometimes in the absence of NK1.1, with CD94 invariably being expressed at two different levels. IL-4 differentially inhibited the expression of CD94 and Ly49 receptors.

  8. Inhibitory receptor CD94 is expressed on mature fetal thymic and adult epidermal TCR Vgamma3+ lymphocytes.

  9. The acquisition of individual receptor gene expressions during various stages of differentiation in culture from embryonic stem cells to NK cells follows a predetermined order, with the order of receptor acquisition being first CD94.

  10. There is no evidence that CD94 inhibits either the lytic function of lymphocytic choriomeningitis virus-specific T cells or their capacity to produce effector cytokines upon peptide stimulation.

  11. The engagement of the activating isoforms of C-type lectin inhibitory receptor (CD94)by their natural ligands, represented by soluble HLA-I molecules, induced programmed cell death of natural killer cells

  12. CD94 heterodimers costimulate effector functions of differentiated Th1 cells, but not Th2 cells.

  13. A high level of expression of CD94/NKG2 receptors is correlated with a lower level of apoptosis and may play an important role in the maintenance of CD8 T and NK cells.

  14. Identification of a novel second CD94 upstream CD94 promoter and the observation that various lymphoid cells use the two promoters differentially offer a theoretical mechanism for the expression of NK receptors on non-NK cells.

  15. the CD94/NKG2A inhibitory receptor plays a critical role in down-regulating invariant NK-cell responses

  16. results indicate that LTbetaR-mediated signals are not required for Ly49 and CD94/NKG2 receptor acquisition on NK cells

  17. CD94-expressing anti-polyoma virus CD8 T cells appear to be essential for antigen-specific recall responses in mice persistently infected by polyoma virus.

  18. CD94 is an Ag that can be used to identify functionally distinct NK cell subsets in mice and could also be relevant to late-stage mouse NK cell development.

Profil protéine Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1)

Profil protéine

Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with KLRD1

  • killer cell lectin like receptor D1 (KLRD1)
  • killer cell lectin-like receptor subfamily D, member 1 (KLRD1)
  • killer cell lectin-like receptor, subfamily D, member 1 (Klrd1)
  • killer cell lectin like receptor D1 (Klrd1)
  • Cd94 Protéine
  • CD94-B Protéine

Protein level used designations for KLRD1

CD94 antigen , KP43 , NK cell receptor , natural killer cells antigen CD94 , killer cell lectin-like receptor family D member 1 , killer cell lectin-like receptor subfamily D member 1 , Killer cell lectin-like receptor subfamily D member 1 , CD94 antigen (located within the rat natural killer gene complex)

GENE ID SPECIES
3824 Homo sapiens
444877 Bos taurus
611360 Canis lupus familiaris
574145 Macaca mulatta
450156 Pan troglodytes
16643 Mus musculus
25110 Rattus norvegicus
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