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Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) Kits ELISA

KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009].. De plus, nous expédions Killer Cell Lectin-Like Receptor Subfamily F, Member 1 Anticorps (20) et Killer Cell Lectin-Like Receptor Subfamily F, Member 1 Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
KLRF1 51348 Q9NZS2
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain
  96 Tests 26 to 36 Days
$899.80
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Humain
  96 Tests 31 to 41 Days
$734.80
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Plus Kits ELISA pour Killer Cell Lectin-Like Receptor Subfamily F, Member 1 partenaires d'interaction

Human Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) interaction partners

  1. NKp80 is a marker of natural killer (NK) cell maturity in secondary lymphoid tissues and supports NK cell development through a stage 4a intermediate with ILC3-associated features.

  2. In the second trimester, functional markers of Decidual natural killer activation, i.e., angiogenic factor production (e.g., vascular endothelial growth factor, interleukin-8, interferon-gamma), remained stable despite an increase in NKp80 or NKG2D surface expression.

  3. IL-15+IL-12 has an immunomodulatory effect on NK cell subsets from HIV-infected individuals viz down-regulation of iNKRs, elevation of activatory receptors NKp46 and NKG2D, and induction of coreceptor NKp80.

  4. our data report a previously unrecognized regulatory circuit enabling autonomous control of human NK cell responses via the NKp80-AICL axis.

  5. Two non-consensus amino acids of NKp80, in particular arginine 6, critically impair both hemi-immunoreceptor tyrosine-based activation motif phosphorylation and Syk recruitment.

  6. Activating receptor NKp80 induces cytotoxicity by using an atypical hemi-ITAM amino acid seqeuence and the Syk-kinase pathway.

  7. NKp80 is expressed on a highly responsive subset of effector memory CD8 T cells with an inflammatory NK-like phenotype and promotes T-cell responses toward AICL-expressing cells.

Chimpanzee Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) interaction partners

  1. phenotypic, molecular, and functional characterization for triggering molecules (NKp46, NKp30 NKp80, and NKG2D; in this AIDS-resistant species, relevant differences to human NK cells involve NKp80 and particularly NKp30

Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) profil antigène

Antigen Summary

KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009

Gene names and symbols associated with KLRF1

  • killer cell lectin like receptor F1 (KLRF1) anticorps
  • CLEC5C anticorps
  • KLRF1 anticorps
  • Lectin-like receptor F1 anticorps
  • nkp80 anticorps

Protein level used designations for KLRF1

C-type lectin domain family 5 member C , activating coreceptor NKp80 , killer cell lectin-like receptor F1 , killer cell lectin-like receptor subfamily F member 1 , lectin-like receptor F1 , killer cell lectin-like receptor subfamily F, member 1 , NKp80 receptor , Activating coreceptor NKp80 , Lectin-like receptor F1 , NKp80 NK receptor

GENE ID SPECIES
51348 Homo sapiens
465281 Pan troglodytes
574389 Macaca mulatta
611429 Canis lupus familiaris
613393 Bos taurus
100144592 Sus scrofa
102141941 Macaca fascicularis
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