Kinesin Family Member 18A (KIF18A) Kits ELISA

KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 [PubMed 15878648]).[supplied by OMIM, Aug 2008].. De plus, nous expédions KIF18A Anticorps (36) et KIF18A Protéines (3) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
KIF18A 81930 Q8NI77
Anti-Souris KIF18A KIF18A 228421 Q91WD7
Anti-Rat KIF18A KIF18A 362186  
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.127 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days

Plus Kits ELISA pour KIF18A partenaires d'interaction

Human Kinesin Family Member 18A (KIF18A) interaction partners

  1. These findings shed new light on the role of Kif18A in chromosome segregation and demonstrate that the spindle assembly checkpoint can be activated at kinetochores that are occupied by fully functional k-Mts that lack tension.

  2. KIF18A expression is a predictive biomarker of drug resistance to endocrine therapy in breast cancer.

  3. High KIF18A expression is associated with invasion and metastasis of hepatocellular carcinoma.

  4. Low post translational modifications of KIF18A protein is associated with neoplasms.

  5. KIF18a role in microtubule assembly

  6. Cdk1-mediated inhibitory phosphorylation of Kif18A promotes chromosome oscillations in early metaphase. PP1 induces metaphase plate thinning by directly dephosphorylating Kif18A.

  7. Confocal microscopy shows that cells expressing SUMO-resistant Kif18A display a compromised dissociation of BubR1 from kinetochores after anaphase onset.

  8. data support a model in which microtubule-attenuating kinesins are molecularly "tuned" to control the dynamics of specific subsets of spindle microtubules

  9. a biomarker for hepatocellular carcinoma diagnosis and an independent predictor of overall survival

  10. that the human mitotic kinesin-8, KIF18A, directly interacts with PP1gamma through a conserved RVxF motif

  11. the motion of yeast (Kip3) and human (Kif18A) kinesin-8s

  12. Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex.

  13. Kif18A (kinesin-8) attenuates centromere movement by directly promoting microtubule pausing in a concentration- dependent manner.

  14. there is a mutual regulation of kinetochore MT plus-end dynamics and Kif18A accumulation, which may contribute to the highly regulated and ordered changes in kinetochore spindle microtubule dynamics during chromosome congression and oscillation

  15. Kif18A controls spindle length independently of its role in chromosome positioning. This is mediated by an ATP-independent spindle microtubule (MT) binding site at C-terminal end of the Kif18A tail that has a strong affinity for MTs in vitro and in cells.

  16. The heightened processivity of Kif18A, conferred by its tail domain, thus promotes concentration of Kif18A at K-MT plus ends, where it suppresses their dynamics to control chromosome movements.

  17. Kif18A overexpression is associated with colorectal cancer progression.

  18. Kinesin (KIF18A) can be potentially used as a blood biomarker to identify asbestosis patients at risk of developing lung cancer.

  19. High Kif18A is associated with breast carcinogenesis.

  20. The kinesin-8 Kif18A dampens microtubule plus-end dynamics.

Mouse (Murine) Kinesin Family Member 18A (KIF18A) interaction partners

  1. Kif18a is specifically required for mitotic progression during germ line development.

  2. In conclusion, Kif18a is critical for colorectal carcinogenesis in the setting of inflammation by mechanisms of increased PI3K-AKT signaling.

KIF18A profil antigène

Antigen Summary

KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005

Gene names and symbols associated with KIF18A

  • kinesin family member 18A L homeolog (kif18a.L) anticorps
  • kinesin family member 18A (KIF18A) anticorps
  • kinesin family member 18A (kif18a) anticorps
  • kinesin family member 18A (Kif18a) anticorps
  • AU024633 anticorps
  • B130001M12Rik anticorps
  • MGC121839 anticorps
  • MS-KIF18A anticorps
  • RGD1561740 anticorps

Protein level used designations for KIF18A

kinesin family member 18A , kinesin-like protein KIF18A , kinesin-like protein KIF18A-like , N-8 kinesin , kinesin superfamily protein 18A

398650 Xenopus laevis
421607 Gallus gallus
451095 Pan troglodytes
485426 Canis lupus familiaris
537566 Bos taurus
548999 Xenopus (Silurana) tropicalis
698453 Macaca mulatta
100030832 Monodelphis domestica
100057621 Equus caballus
100345219 Oryctolagus cuniculus
100446373 Pongo abelii
100467416 Ailuropoda melanoleuca
100518110 Sus scrofa
100547630 Meleagris gallopavo
100564606 Anolis carolinensis
100597580 Nomascus leucogenys
81930 Homo sapiens
228421 Mus musculus
362186 Rattus norvegicus
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