LETM1 Domain Containing 1 (LETMD1) Kits ELISA

Human LETM1 Domain Containing 1 (LETMD1) interaction partners

1. Data show that the activation of STAT3 protein upregulated human cervical cancer oncogene (HCCR) expression in gastric cancer cells.

2. Demonstrate that HBx-HCCR-E-cadherin regulation pathway might play an important role in HBV-induced hepatocarcinogenesis.

3. These findings suggest that HCCR gene is over-expressed in acute leukemia patients and may be a useful biomarker for monitoring minimal residual disease.

4. HCCR2 gene plays an important role in the tumorigenesis of leukemia.

5. HCCRBP-3 induces tumorigenesis through direct interaction with HCCR-1 in human cancers.

6. The data demonstrate that HCCR-1 may be used as a novel predictor for the prognosis of the patients with esophageal squamous cell carcinoma.

7. HCCR-1 might play a role in the breast tumourigenesis while the overexpression of HCCR-1 induces the obesity probably by inhibiting the cholesterol-lowering effect of ApoE

8. The overexpression of HCCR-2 could enhance the division and proliferation of SMMC 7721 cells.

9. induces neoplastic cell transformation and epithelial-mesenchymal transdifferentiation

10. Treatment of PANC-1 cells with epidermal growth factor increased HCCR-1 protein level via PI3K/Akt/mTOR signaling.

11. Human, similar to bacterial ribosomal protein L14 and yeast L22, gene L14.22 (clone 507E08), over-expressed in gliomas.

12. HCCR-2 probably represents a new oncogene that is related to tumorigenesis, functioning as a negative regulator of the p53 tumor suppressor

13. HCCR-2 represents an oncoprotein that is related to breast cancer development and regulation of the p53 tumor suppressor.

14. HCCR oncoprotein has a role in development of human breast cancer

15. These results suggest that the HCCR-1 oncogene expression was regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway.

16. These experiments show the biological features of HCCR-1 in the cell, and suggest that uncontrolled expression of HCCR-1 may cause mitochondrial dysfunction.

17. Data indicate that the level of HCCR-1 in breast cancer tissues is correlated with the HER2 overexpression, p53 mutation, and ER/PR status, and determination of HCCR-1 levels as options for HER2 testing is promising although it needs further evaluation.

18. TCF and beta-catenin binding plays important roles in HCCR-1 oncogene expression.

Mouse (Murine) LETM1 Domain Containing 1 (LETMD1) interaction partners

1. HCCR-1 might play a role in the breast tumourigenesis while the overexpression of HCCR-1 induces the obesity probably by inhibiting the cholesterol-lowering effect of ApoE

2. The level of HCCR-1 expression was increased during the mouse embryogenesis and expression of phosphatidylinositol 3-kinase (PI3K) in NIH/3T3 cells activated the HCCR-1 promoter.