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LETMD1 encodes a mitochondrial outer membrane protein. De plus, nous expédions LETM1 Domain Containing 1 Anticorps (43) et LETM1 Domain Containing 1 Protéines (10) et beaucoup plus de produits pour cette protéine.
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Data show that the activation of STAT3 protein upregulated human cervical cancer oncogene (HCCR) expression in gastric cancer cells.
Demonstrate that HBx-HCCR-E-cadherin regulation pathway might play an important role in HBV-induced hepatocarcinogenesis.
These findings suggest that HCCR gene is over-expressed in acute leukemia patients and may be a useful biomarker for monitoring minimal residual disease.
HCCR2 gene plays an important role in the tumorigenesis of leukemia.
HCCRBP-3 induces tumorigenesis through direct interaction with HCCR-1 in human cancers.
The data demonstrate that HCCR-1 may be used as a novel predictor for the prognosis of the patients with esophageal squamous cell carcinoma.
HCCR-1 might play a role in the breast tumourigenesis while the overexpression of HCCR-1 induces the obesity probably by inhibiting the cholesterol-lowering effect of ApoE
The overexpression of HCCR-2 could enhance the division and proliferation of SMMC 7721 cells.
induces neoplastic cell transformation and epithelial-mesenchymal transdifferentiation
Treatment of PANC-1 cells with epidermal growth factor increased HCCR-1 protein level via PI3K/Akt/mTOR signaling.
Human, similar to bacterial ribosomal protein L14 and yeast L22, gene L14.22 (clone 507E08), over-expressed in gliomas.
HCCR-2 probably represents a new oncogene that is related to tumorigenesis, functioning as a negative regulator of the p53 tumor suppressor
HCCR-2 represents an oncoprotein that is related to breast cancer development and regulation of the p53 tumor suppressor.
HCCR oncoprotein has a role in development of human breast cancer
These results suggest that the HCCR-1 oncogene expression was regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway.
These experiments show the biological features of HCCR-1 in the cell, and suggest that uncontrolled expression of HCCR-1 may cause mitochondrial dysfunction.
Data indicate that the level of HCCR-1 in breast cancer tissues is correlated with the HER2 overexpression, p53 mutation, and ER/PR status, and determination of HCCR-1 levels as options for HER2 testing is promising although it needs further evaluation.
TCF and beta-catenin binding plays important roles in HCCR-1 oncogene expression.
The level of HCCR-1 expression was increased during the mouse embryogenesis and expression of phosphatidylinositol 3-kinase (PI3K) in NIH/3T3 cells activated the HCCR-1 promoter.
This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene.
LETM1 domain-containing protein 1
, cervical cancer 1 proto-oncogene protein p40
, cervical cancer proto-oncogene 2 protein
, regulator of TP53
, cervical cancer receptor