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LHX9 encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors.
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Human Polyclonal LHX9 Primary Antibody pour IHC, IHC (p) - ABIN4330942
Li, Ponten, dos Remedios: The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development. dans Proteomics 2012
the Lhx9-integrin-paxillin (Montrer PXN Anticorps) pathway has a role in proepicardial organ positioning and epicardial formation
Substantial evidence is found for the existence of a ventral pallium, based on Lhx9 expression in the forebrain during larval development and in the adult.
while FGF signalling initiates and maintains brain XLhx9 expression, in the eye primordium the requirement of FGFs for expression is rapidly lost.
Lhx9 is sufficient to specify Hcrt (Montrer OX Anticorps)-expressing neurons in the developing mouse hypothalamus.
Lack of Lhx2 (Montrer LHX2 Anticorps)/Lhx9 function as well as increased Wnt (Montrer WNT2 Anticorps) signaling alter the expression of the thalamus specific cell adhesion factor pcdh10b and lead subsequently to a striking anterior-posterior disorganization of the caudal (Montrer CAD Anticorps) forebrain.
Lhx9 and Lhx1 (Montrer LHX1 Anticorps) serve as a binary switch in controlling the rostral versus caudal (Montrer CAD Anticorps) longitudinal turning of the caudal (Montrer CAD Anticorps) commissural axons. Lhx1 (Montrer LHX1 Anticorps) determines caudal (Montrer CAD Anticorps) turning and Lhx9 triggers rostral turning.
LHX9 gene is frequently silenced in pediatric malignant astrocytomas
Authors examined the expression pattern for the three alternative splice forms of Lhx9; Lhx9alpha, Lhx9beta and Lhx9c during early limb development.
Study has revealed that Lhx9 plays a role in the development of the pineal gland and in maintenance of the brain structure.
Lhx9-GCE mouse line could serve as a beneficial tool for lineage tracing and gene manipulation experiments.
Gbx2 (Montrer GBX2 Anticorps) regulates thalamocortical axon guidance by modifying the LIM (Montrer PDLIM5 Anticorps) and Robo codes.
a pathway in which the products of the Wt1 (Montrer WT1 Anticorps) and Lhx9 genes activate expression of Sf1 (Montrer SF1 Anticorps) and thus mediate early gonadogenesis
the Lhx9 gene represents the first direct target of the GATA4 (Montrer GATA4 Anticorps)/FOG2 (Montrer ZFPM2 Anticorps) repressor complex in cardiac development.
Lhx2 (Montrer LHX2 Anticorps)/9 regulate directly the expression of Rig-1 (Montrer ROBO3 Anticorps). And expressed by a set of commissural relay neurons and are required for the this neuron axon projection.
The second wave of expression at E12.5 includes Lhx3 (Montrer LHX3 Anticorps), 5, 9, Isl2 (Montrer ISL2 Anticorps), and Lmx1b (Montrer LMX1B Anticorps) in the differentiating sensory epithelia with cellular specificities.
This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants.
LIM homeobox 9
, LIM homeobox protein 9
, LIM/homeobox protein Lhx9
, LIM/homeobox protein Lhx9-like
, LIM homeodomain type transcription factor Lhx9
, homeobox protein
, LIM-homeobox protein 9
, LIM homeobox 9-like
, LIM-homeodomain type transcription factor 9