Laeverin Protéines (AQPEP)

Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo- maternal interface. De plus, nous expédions AQPEP Kits (8) et AQPEP Anticorps (5) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
Rat AQPEP AQPEP 502160  
AQPEP 206338 Q6Q4G3
AQPEP 74574  
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Top AQPEP Protéines sur anticorps-enligne.fr

Showing 4 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 60 to 65 Days
$10,888.92
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails

AQPEP Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, , ,
Mouse (Murine)
,

Plus protéines pour Laeverin (AQPEP) partenaires d'interaction

Human Laeverin (AQPEP) interaction partners

  1. Laeverin is expressed in all trophoblast cell types of normal and preeclamptic placentas. Expression pattern of laeverin in trophoblast cells is heterogeneous and not necessarily membrane-bound.

  2. In preeclamptic placentas, laeverin is experssed in the cytoplasm and microvesicles, rather than the cell membrane. Laeverin appears to be involved in trophoblast cell migration and invasion through interaction with integrins and matrix metalloprotease 1 (Montrer MMP1 Protéines).

  3. Laeverin is a specific cell-surface marker for human extravillous trophoblast (EVT) and plays a regulatory role in EVT migration.

  4. Replacement of glutamine-238 with alanine caused a significant change in substrate specificity rather than a decrease in enzymatic activity.

  5. These results indicate that His(379) of laeverin plays essential roles in its distinctive enzymatic properties and contributes to maintaining the appropriate structure of the catalytic cavity of the enzyme.

  6. Extravillous trophoblasts express laeverin, a novel protein that belongs to membrane-bound gluzincin metallopeptidases(laeverin)

  7. The 3 most significantly overexpressed genes in rheumatoid arthritis were laeverin, 11beta-hydroxysteroid dehydrogenase type 2 (a steroid pathway enzyme), and cysteine-rich, angiogenic inducer 61 (a known angiogenic factor (Montrer VEGFA Protéines)).

  8. is a novel bestatin-sensitive leucine aminopeptidase (Montrer LAP Protéines); plays important roles in human placentation by regulating biological activity of key peptides at the embryo-maternal interface

  9. A novel membrane-bound cell surface peptidase, laeverin (FLJ90650), was found to be specifically expressed on extravillous trophoblasts that had almost ceased invasion into maternal decidual tissues.

Profil protéine AQPEP

Profil protéine

Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo- maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met- MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C.

Gene names and symbols associated with Laeverin Protéines (AQPEP)

  • laeverin (Lvrn)
  • laeverin (LVRN)
  • APQ Protéine
  • Aqpep Protéine
  • LVRN Protéine
  • RGD1562779 Protéine

Protein level used designations for Laeverin Protéines (AQPEP)

aminopeptidase Q , laeverin , AP-Q , CHL2 antigen

GENE ID SPECIES
502160 Rattus norvegicus
525695 Bos taurus
696886 Macaca mulatta
100353757 Oryctolagus cuniculus
206338 Homo sapiens
74574 Mus musculus
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