Leucine Rich Repeat and Ig Domain Containing 1 Protéines (LINGO1)

May play a role in regulating axonal regeneration and plasticity in the adult central nervous system (By similarity). De plus, nous expédions LINGO1 Anticorps (127) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
LINGO1 84894 Q96FE5
LINGO1 235402 Q9D1T0
Rat LINGO1 LINGO1 315691  
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Showing 4 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 50 to 55 Days
$7,626.01
Détails
Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 11 to 12 Days
$225.40
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails

LINGO1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, , ,
Mouse (Murine)
,

Plus protéines pour Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) partenaires d'interaction

Human Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) interaction partners

  1. LINGO1 rs11856808 plays a protective role by decreasing the risk for PD, but not for MSA (Montrer TPO Protéines), in Chinese population.

  2. LINGO1 protein acts as a gateway protein internalizing into the tumor cells when engaged by antibody and can carry antibody conjugated with drugs to kill Ewing sarcoma cells.

  3. Data indicate that leucine-rich repeat neuronal protein 1 (LINGO-1) is intracellular and competes with Nogo-66 receptor (NgR (Montrer RTN4R Protéines)) for binding to p75 neurotrophin receptor (p75NTR (Montrer NGFR Protéines)).

  4. The results of this study show Increased LINGO1 in the cerebellum of essential tremor patients.

  5. Lingo-1 signaling is altered in the schizophrenia brain.

  6. LINGO-1 can directly bind to ErbB2 (Montrer ERBB2 Protéines), block ErbB2 (Montrer ERBB2 Protéines) translocation into lipid rafts, and inhibit its phosphorylation.

  7. This review found that several gene variants in the LINGO1 gene may increase the risk of essential tremor.

  8. LINGO1 variants are associated with essential tremor in Chinese Han female patients.

  9. LINGO-1 potentiates neuronal apoptosis, likely by inhibiting WNK3 kinase activity.

  10. Results of a meta-analysis suggest a relationship between LINGO1 rs11856808 polymorphism and risk of essential tremor (ET) and familial ET, while rs9652490 polymorphism is only associated with the risk for familial ET.

Mouse (Murine) Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) interaction partners

  1. These data provide morphometric and functional evidence of enhancement of remyelination associated with antagonism of LINGO-1

  2. LINGO-1, a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions

  3. a novel role for LINGO-1 in neural stem cell differentiation to neurons

  4. inhibitory agents of LINGO-1 activity can protect dopaminergic neurons against degeneration

  5. Lingo1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis.

Profil protéine LINGO1

Profil protéine

May play a role in regulating axonal regeneration and plasticity in the adult central nervous system (By similarity).

Gene names and symbols associated with LINGO1

  • leucine rich repeat and Ig domain containing 1 (LINGO1)
  • leucine rich repeat and Ig domain containing 1 (lingo1)
  • leucine rich repeat and Ig domain containing 1 (Lingo1)
  • 4930471K13Rik Protéine
  • AV148400 Protéine
  • DKFZp459P0736 Protéine
  • LERN1 Protéine
  • LINGO-1 Protéine
  • Lrrn6a Protéine
  • UNQ201 Protéine

Protein level used designations for LINGO1

leucine rich repeat and Ig domain containing 1 , leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 , Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 , leucine rich repeat neuronal 6A , leucine-rich repeat and immunoglobilin domain-containing protein 1 , leucine-rich repeat and immunoglobulin domain-containing protein 1 , leucine-rich repeat neuronal protein 1 , leucine-rich repeat neuronal protein 6A , leucine-rich repeat neuronal 6A , cLINGO-1

GENE ID SPECIES
453764 Pan troglodytes
100061441 Equus caballus
100101739 Xenopus (Silurana) tropicalis
100171931 Pongo abelii
100228050 Taeniopygia guttata
84894 Homo sapiens
235402 Mus musculus
415344 Gallus gallus
487660 Canis lupus familiaris
100155465 Sus scrofa
520694 Bos taurus
315691 Rattus norvegicus
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