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LIPH encodes a membrane-bound member of the mammalian triglyceride lipase family. De plus, nous expédions LIPH Kits (18) et LIPH Protéines (8) et beaucoup plus de produits pour cette protéine.
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We finally isolate control and Enpp2 (Montrer ENPP2 Anticorps)-null dermal pipilla precursors and identify the expression and upregulation of LIPH, an alternative LPA (Montrer LPA Anticorps)-producing enzyme, suggesting that this gene could functionally compensate for the absence of Enpp2 (Montrer ENPP2 Anticorps).
The present study shows 93% of Japanese patients with ARWH had at least one of the two founder mutations in exon 6 of LIPH (Montrer LIPC Anticorps). Highly prevalent founder mutations in LIPH (Montrer LIPC Anticorps).
The authors report no apparent decrease in total hair count but remarkable miniaturization and increased telogen/anagen hair ratio in patients homozygous mutations in LIPH (Montrer LIPC Anticorps).
This meta-analysis demonstrates that the T allele in the LIPC (Montrer LIPC Anticorps) rs493258 polymorphism was significantly associated with the risk of any and late age related macular degeneration
Our data suggest that LIPH (Montrer LIPC Anticorps) may have prognostic value for esophageal cancer.
sequencing LIPH (Montrer LIPC Anticorps) identi fi ed a novel non-sense mutation (c.328C>T; p.Arg110*) in one and a previously reported 2-bp deletion mutation (c.659_660delTA, p.Ile220ArgfsX29) in three other families.
A heterozygous missense mutation c.736T>A (p.Cys246Ser) in exon 6 of the LIPH (Montrer LIPC Anticorps) gene of both the affected individuals was identified. In addition, we also found that both patients carried heterozygous sequences in exon 5 of the LIPH (Montrer LIPC Anticorps) gene.
The study further extends the body of evidence that sequence variants in the LIPH (Montrer LIPC Anticorps) gene result in hypotrichosis and woolly hair phenotype.
High LIPH (Montrer LIPC Anticorps) expression is associated with metastasis in breast cancer.
Mutation patterns of LIPH (Montrer LIPC Anticorps) might be associated with hypotrichosis severity in autosomal recessive woolly hair/hypotrichosis.
Immunohistochemistry detected LIPH (Montrer LIPC Anticorps) expression in most of the adenocarcinomas and bronchioloalveolar carcinomas obtained from lung cancer patients. LIPH (Montrer LIPC Anticorps) expression was also observed less frequently in the squamous lung cancer tissue samples.
Results show the LIPH mode of action and confirm the crucial role of LIPH in hair production.
association between a deletion of a single nucleotide in LIPH exon and rex phenotype
This gene encodes a membrane-bound member of the mammalian triglyceride lipase family. It catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility.
, lipase member H
, LPD lipase-related protein
, mPA-PLA1 alpha
, membrane-associated phosphatidic acid-selective phospholipase A1-alpha
, membrane-bound phosphatidic acid-selective phospholipase A1
, phospholipase A1 member B
, lacrimal lipase