Loricrin Protéines (LOR)

LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. De plus, nous expédions Loricrin Anticorps (19) et Loricrin Kits (7) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
LOR 4014 P23490
Souris LOR LOR 16939 P18165
Rat LOR LOR 502541  
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Chemical His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
Wheat germ Chemical GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
Escherichia coli (E. coli) Humain His tag,GST tag 100 μg Connectez-vous pour afficher 15 to 18 Days

LOR Protéines protéines par origine et source

Origin Exprimée danse Conjugué

Plus protéines pour Loricrin (LOR) partenaires d'interaction

Human Loricrin (LOR) interaction partners

  1. Authors report a multi-generation family with prominent ichthyosis (Montrer LBR Protéines) and palmoplantar involvement due to a novel mutation in loricrin.

  2. Letter: Knockdown of either filaggrin (Montrer FLG Protéines) or loricrin increases the productions of interleukin (IL)-1alpha, IL-8 (Montrer IL8 Protéines), IL-18 (Montrer IL18 Protéines) and granulocyte macrophage colony-stimulating factor (Montrer CSF2 Protéines) in stratified human keratinocytes.

  3. Studies on human keratinocytes recognized that loricrin expression was inversely related to the expression of the cyclin-dependent kinase (Montrer CDK1 Protéines) inhibitor p21 (Montrer CDKN1A Protéines)

  4. two novel heterozygous frameshift mutations in exon 2 - c.646_647insGCAGCAGGTC, p.Gln216Argfs*123 and c.798_799dupT, p.Gly267Trpfs*69 in loricrin keratoderma patients

  5. Results describe a novel frameshift mutation leading to loricrin keratoderma presenting with colloidion membrane

  6. We found no mutations of Loricrin in two Progressive symmetrical erythrokeratoderma families.

  7. We describe a young man who was a collodion baby and had the typical presentation of Loricrin keratoderma. Direct DNA sequencing identified a heterozygous mutation in the loricrin gene with a single G insertion, 730insG, present in (a) the patient

  8. There were no mutations found in the LOR gene and the true pathogenesis of progressive symmetrical erythrokeratodermia remains unknown.

  9. identified mRNA transcripts from three genes CDSN (Montrer CDSN Protéines), LOR and KRT9 (Montrer KRT9 Protéines), showing strong over-expression in skin samples relative to samples from forensic body fluids, making them suitable markers for skin identification

  10. VEGF (Montrer VEGFA Protéines) release and the subsequent activation of VEGF receptor 2 link loricrin gene mutations to rapid cell proliferation in a cellular model of loricrin keratoderma.

Mouse (Murine) Loricrin (LOR) interaction partners

  1. the late cornified envelope 1 proteins are regulated by NRF2 (Montrer NFE2L2 Protéines) and are compensatory components for loricrin as determined by their localization within the loricrin knockout cell envelope via immunoelectron microscopy

  2. Oct-6 and Oct-11 contribute to the regulation of loricrin gene transcription via interaction with AP-1 factors and Sp1/Sp3.

  3. In the absence of loricrin, S. aureus nasal colonisation was significantly impaired.

  4. The decreased expression of epidermal growth factor receptor (EGFR (Montrer EGFR Protéines)), E-cadherin (Montrer CDH1 Protéines), occludin (Montrer OCLN Protéines), and SIRT1 (Montrer SIRT1 Protéines) in the skin of Flg(ft (Montrer FLG Protéines)) mice, compared with those in C57BL/6J mice, is reported.

  5. These results indicate AASS (Montrer AASS Protéines) knockdown decreases the lysine requirement of the cell via a reduction of lysine catabolism through the saccharopine pathway.

  6. Mice receiving the high-protein diet had greater AASS (Montrer AASS Protéines) mRNA compared to mice fed the adequate protein diet.

  7. YY1 (Montrer YY1 Protéines) contributes to specific loricrin gene expression in differentiated keratinocytes by suppression of its transcription in undifferentiated keratinocytes.

  8. nectin-1 (Montrer PVRL1 Protéines) plays a key role in the expression of loricrin in the epidermis

  9. Skin biopsies from STAT6 (Montrer STAT6 Protéines) transgenic mice were deficient in the expression and production of loricrin and involucrin (Montrer IVL Protéines).

Profil protéine Loricrin (LOR)

Profil protéine

This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.

Gene names and symbols associated with Loricrin Protéines (LOR)

  • loricrin (LOR)
  • loricrin (Lor)
  • loricrin (TVAG_146950)
  • loricrin (TVAG_228830)
  • loricrin (TVAG_228920)
  • loricrin (TVAG_238290)
  • loricrin (TVAG_035050)
  • loricrin (TVAG_070680)
  • Loricrin (Bm1_52290)
  • loricrin (LOC100281109)
  • loricrin (LOC100281170)
  • aminoadipate-semialdehyde synthase (Aass)
  • AI036317 Protéine
  • LKR Protéine
  • LKR/SDH Protéine
  • LOR Protéine
  • LOR/SDH Protéine
  • Lorsdh Protéine
  • RGD1559993 Protéine
  • S77319 Protéine
  • SDH Protéine

Protein level used designations for Loricrin Protéines (LOR)

RGD1559993 , loricrin , Loricrin , alpha-aminoadipic semialdehyde synthase, mitochondrial , lysine oxoglutarate reductase , saccharopine dehydrogenase

4014 Homo sapiens
16939 Mus musculus
502541 Rattus norvegicus
505154 Bos taurus
609440 Canis lupus familiaris
714526 Macaca mulatta
5464469 Trichomonas vaginalis G3
5465148 Trichomonas vaginalis G3
5465157 Trichomonas vaginalis G3
5467355 Trichomonas vaginalis G3
5468010 Trichomonas vaginalis G3
5468969 Trichomonas vaginalis G3
6105342 Brugia malayi
100281109 Zea mays
100281170 Zea mays
30956 Mus musculus
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