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Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. De plus, nous expédions LRP10 Protéines (9) et beaucoup plus de produits pour cette protéine.
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In Mayer-Rokitansky-Kuster-Hauser syndrome in monoztgotic twins, LRP10 (Montrer LRP4 Anticorps) was identified as one of the candidate genes.
Increased expression of LRP10 (Montrer LRP4 Anticorps) in human neuroblastoma (Montrer ARHGEF16 Anticorps) SH-SY5Y cells induces the accumulation of mature APP (Montrer APP Anticorps) in the Golgi and reduces its presence at the cell surface and its processing into Abeta (Montrer APP Anticorps).
LRP10 (Montrer LRP4 Anticorps) may interfere with the formation of the beta-catenin (Montrer CTNNB1 Anticorps)/TCF (Montrer HNF4A Anticorps) complex and/or its binding to target DNA in the nucleus, and that the extracellular domain of LRP10 (Montrer LRP4 Anticorps) is critical for inhibition of the canonical Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signaling pathway.
These results suggest that LRP9 cycles between the trans-Golgi network, endosomes and the plasma membrane through a GGA dependent-trafficking mechanism.
Data show that Calnuc (Montrer NUCB1 Anticorps) is involved in LRP9 endosomal sorting to prevent the delivery of LRP9 to lysosomes.
Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver.
, low-density lipoprotein receptor-related protein 10