anti-Lysine (K)-Specific Demethylase 1B (KDM1B) Anticorps

Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).[supplied by OMIM, Oct 2009].. De plus, nous expédions KDM1B Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
KDM1B 221656 Q8NB78
KDM1B 218214 Q8CIG3
KDM1B 513667  
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Top anti-KDM1B Anticorps sur anticorps-enligne.fr

Showing 10 out of 41 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 2:Western blot analysis using AOF1 mAb against human AOF1 (AA: 6-129) recombinant protein. (Expected MW is 40 kDa) Dilution: 1/500 - 1/2000 100 μL Connectez-vous pour afficher 8 to 11 Days
$577.50
Détails
Humain Lapin Inconjugué ELISA 50 μL Connectez-vous pour afficher 2 to 3 Days
$185.00
Détails
Humain Souris Inconjugué CyTOF, ELISA, FACS, ICC, IF, IHC, WB Western Blot: AOF1 Antibody (5E10C1)  - Analysis using AOF1 mAb against HEK293 (1) and AOF1 (AA: 6-129)-hIgGFc transfected HEK293 (2) cell lysate. Immunofluorescence: AOF1 Antibody (5E10C1)  - Immunofluorescence analysis of HeLa cells using AOF1 mouse mAb. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$516.98
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB Anti-KDM1B antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 0.05 mg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: AOF1 Antibody [NBP1-90148] - Immunohistochemical staining of human liver shows nuclear and cytoplasmic positivity in hepatocytes. Immunocytochemistry/Immunofluorescence: AOF1 Antibody [NBP1-90148] - Staining of human cell line A-431 shows positivity in nucleus. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Souris Inconjugué Fig. 1. Black line: Control Antigen (100 ng) 100 μg Connectez-vous pour afficher 11 to 16 Days
$469.05
Détails
Souris Lapin Inconjugué WB KDM1B / LSD2 antibody (pAb) tested by Western blot. Nuclear extract of NIH3T3 cells (40 µg) probed with KDM1B / LSD2 antibody (pAb) at a dilution of 1:500. 100 μL Connectez-vous pour afficher 1 to 2 Days
$507.50
Détails
Humain Lapin Inconjugué ELISA, WB   0.1 mg Connectez-vous pour afficher 2 to 3 Days
$360.00
Détails
Humain Lapin Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 15 to 19 Days
$527.03
Détails

anti-KDM1B Anticorps mieux référencés

  1. Human Polyclonal KDM1B Primary Antibody pour ICC, IF - ABIN4280857 : Katz, Vasilatos, Harrington, Oesterreich, Davidson, Huang: Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells. dans Breast cancer research and treatment 2014 (PubMed)

Plus d’anticorps contre KDM1B partenaires d’interaction

Human Lysine (K)-Specific Demethylase 1B (KDM1B) interaction partners

  1. These results suggest that LSD2 achieves a promoting effect on small cell lung cancer by indirectly regulating TFPI2 expression through the mediation of DNMT3B expression or through the regulation of the demethylation of H3K4me1 in the promoter region of the TFPI2 gene.

  2. This review focuses on published small-molecule inhibitors targeted at the two flavin adenine dinucleotide-dependent lysine demethylases, lysine-specific demethylases 1 and 2, and how the inhibitors interact with the tertiary structures of the enzymes.

  3. These results demonstrate an important role for LSD2 in regulation of DNA methylation and gene silencing in breast cancer.

  4. Histone demethylase LSD2 acts as an E3 ubiquitin ligase and inhibits cancer cell growth through promoting proteasomal degradation of OGT.

  5. Using transcriptome and chromatin immunoprecipitation-sequencing analyses, the study revealed that LSD2 represses the genes involved in lipid influx and metabolism through demethylation of histone H3K4.

  6. regulation of tissue factor pathway inhibitor-2 (TFPI-2) expression by lysine-specific demethylase 1 and 2

  7. The zinc finger-SWIRM-oxidase domains is required for KDM1B demethylase activity and the binding of FAD.

  8. Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.

Mouse (Murine) Lysine (K)-Specific Demethylase 1B (KDM1B) interaction partners

  1. reveal a direct role of hypoxia-inducible factor in regulating miRNA biogenesis and consequently activating the miR-215-KDM1B-mediated signaling required for glioma-initiating cells adaptation to hypoxia

  2. Data indicate that Myst4, Jmjd2b, Aof1 genes are regulated by H3K9me under hyperinsulinemia/hyperglycemia.

  3. AOF1 is the second histone demethylase in the family of flavin-dependent amine oxidases and reveals a demethylase-independent repression function.

  4. oocytes from KDM1B-deficient females showed a substantial increase in H3K4 methylation and failed to set up the DNA methylation marks at four out of seven imprinted genes examined

KDM1B profil antigène

Profil protéine

Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009

Gene names and symbols associated with KDM1B

  • lysine demethylase 1B (KDM1B) anticorps
  • lysine-specific histone demethylase 1B (LOC577549) anticorps
  • lysine (K)-specific demethylase 1B (kdm1b) anticorps
  • lysine demethylase 1B (kdm1b) anticorps
  • lysine (K)-specific demethylase 1B (Kdm1b) anticorps
  • 4632428N09Rik anticorps
  • AI482520 anticorps
  • Aof1 anticorps
  • bA204B7.3 anticorps
  • C6orf193 anticorps
  • dJ298J15.2 anticorps
  • LSD2 anticorps

Protein level used designations for KDM1B

amine oxidase (flavin containing) domain 1 , lysine (K)-specific demethylase 1B , lysine-specific histone demethylase 1B-like , amine oxidase, flavin containing 1 , flavin-containing amine oxidase domain-containing protein 1 , lysine-specific histone demethylase 1B , lysine-specific histone demethylase 2

GENE ID SPECIES
513667 Bos taurus
577549 Strongylocentrotus purpuratus
100066240 Equus caballus
100401095 Callithrix jacchus
100443986 Pongo abelii
100481180 Ailuropoda melanoleuca
100489838 Xenopus (Silurana) tropicalis
100547778 Meleagris gallopavo
100552653 Anolis carolinensis
221656 Homo sapiens
218214 Mus musculus
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