Lysine (K)-Specific Demethylase 4D Protéines (KDM4D)

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. De plus, nous expédions Lysine (K)-Specific Demethylase 4D Anticorps (63) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
KDM4D 55693 Q6B0I6
KDM4D 244694 Q3U2K5
KDM4D 689582 A1A5Q5
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Top Lysine (K)-Specific Demethylase 4D Protéines sur anticorps-enligne.fr

Showing 6 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$9,797.11
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$9,797.11
Détails
Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 11 to 12 Days
$338.33
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,448.50
Détails
Baculovirus Humain DYKDDDDK Tag JMJD2D / KDM4D activity assay. Recombinant JMJD2D / KDM4D activity measured using a demethylation assay. MALDI-TOF was used for detection. Recombinant JMJD2D / KDM4D activity using AlphaLISA. JMJD2D / KDM4D was used in an AlphaLISA assay to determine enzyme titration. An IC50 dose response assessment of reference compounds 2,4-PDCA and N-OG is shown. This data was generated and kindly provided courtesy of ChemPartner. 20 μg Connectez-vous pour afficher 1 to 2 Days
$472.50
Détails
Escherichia coli (E. coli) Humain Inconjugué   5 applications Connectez-vous pour afficher 1 to 2 Days
$318.85
Détails

KDM4D Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Plus protéines pour Lysine (K)-Specific Demethylase 4D (KDM4D) partenaires d'interaction

Human Lysine (K)-Specific Demethylase 4D (KDM4D) interaction partners

  1. A high nuclear expression of KDM4D in samples of pancreatic resection margins significantly and independently predicted an earlier recurrence and could thus be used in the assessment of risk of relapse in clinical practice.

  2. The results demonstrate a novel mechanism by which Kdm4d regulates DNA replication by reducing the H3K9me3 level to facilitate formation of preinitiation complex.

  3. KDM4B and KDM4D expression may associate with an aggressive subtype of classical Hodgkin lymphoma and be linked with radioresistance

  4. KDM4D-RNA interaction is required for KDM4D accumulation at DNA breakage sites

  5. PARP1 (Montrer PARP1 Protéines)-dependent recruitment of KDM4D histone demethylase (Montrer MBD2 Protéines) to DNA damage sites promotes double-strand break repair.

  6. The molecular basis for JMJD2 (Montrer KDM4A Protéines) site specificity revealed by X-ray crystallography.

  7. Results demonstrate that JMJD2D can stimulate cell proliferation and survival, suggesting that its inhibition may be helpful in the fight against cancer

  8. identified two related histone demethylases, JMJD2A (Montrer KDM4A Protéines) and JMJD2D

Mouse (Murine) Lysine (K)-Specific Demethylase 4D (KDM4D) interaction partners

  1. These results suggest that demethylation of H3K9 in round spermatids is dispensable for spermatogenesis but that possible defects in Kdm4d-null elongating spermatids could be rescued by functional redundancy of the KDM4B demethylase (Montrer MBD2 Protéines).

Profil protéine Lysine (K)-Specific Demethylase 4D (KDM4D)

Profil protéine

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys- 9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).

Gene names and symbols associated with KDM4D

  • lysine demethylase 4D (KDM4D)
  • lysine-specific demethylase 4D (LOC524768)
  • lysine (K)-specific demethylase 4D (Kdm4d)
  • lysine-specific demethylase 4D (LOC617971)
  • lysine-specific demethylase 4D (LOC100067461)
  • lysine demethylase 4D (Kdm4d)
  • lysine-specific demethylase 4D (LOC698455)
  • lysine (K)-specific demethylase 4D (KDM4D)
  • lysine-specific demethylase 4D (LOC100514356)
  • 4932416A15 Protéine
  • Jmjd2d Protéine
  • KDM4D Protéine

Protein level used designations for KDM4D

jmjC domain-containing histone demethylation protein 3D , jumonji domain containing 2D , jumonji domain-containing protein 2D , lysine-specific demethylase 4D , lysine (K)-specific demethylase 4D , lysine-specific demethylase 4D-like

GENE ID SPECIES
55693 Homo sapiens
524768 Bos taurus
244694 Mus musculus
466754 Pan troglodytes
617971 Bos taurus
100067461 Equus caballus
689582 Rattus norvegicus
698455 Macaca mulatta
100408074 Callithrix jacchus
100475904 Ailuropoda melanoleuca
100514356 Sus scrofa
100597675 Nomascus leucogenys
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