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Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. De plus, nous expédions Lysophospholipase I Protéines (19) et Lysophospholipase I Kits (4) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 65 products:
Human Polyclonal LYPLA1 Primary Antibody pour ELISA, WB - ABIN564540
Vose, Fujioka, Gulevich, Lin, Holland, Casida: Cellular function of neuropathy target esterase in lysophosphatidylcholine action. dans Toxicology and applied pharmacology 2008
Human Monoclonal LYPLA1 Primary Antibody pour IF, ELISA - ABIN523832
Hirano, Kishi, Sugimoto, Taguchi, Obinata, Ohshima, Tatei, Izumi: Thioesterase activity and subcellular localization of acylprotein thioesterase 1/lysophospholipase 1. dans Biochimica et biophysica acta 2009
Data show taht active S-depalmitoylation in mitochondria, in part mediated by acyl-protein thioesterase 1 (APT1)
Here, we describe the conserved functions of APT1 (Montrer FAS Anticorps) and APT2 (Montrer TAP2 Anticorps) across organisms and discuss the possibility that these enzymes are members of a larger family of depalmitoylation enzymes.
High expression of APT1 (Montrer FAS Anticorps) is associated with chronic lymphocytic leukemia.
identifcation APT1 (Montrer FAS Anticorps) as one of the thioesterases in the acylation cycle and demonstration that this protein is a cellular target of the inhibitor.
Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 (Montrer LYPLA2 Anticorps) with that of proto-oncogene (Montrer RAB1A Anticorps) H-ras (Montrer HRAS Anticorps) product and growth-associated protein-43 (Montrer GAP43 Anticorps)
Serum activity of APT1 (Montrer FAS Anticorps) may play an important role in determination of the concentration of des (Montrer DES Anticorps)-acyl ghrelin (Montrer GHRL Anticorps) in circulation, especially under septic inflammation.
Endogenous and overexpressed hAPT1 were mainly localized in the cytosol, while some signals were detected in the plasma membrane, the nuclear membrane and endoplasmic reticulum in HEK293 cells.
Results suggest that APT1 (Montrer FAS Anticorps)-regulated depalmitoylation of Galpha (Montrer SUCLG1 Anticorps)(13) might be an important downstream event of miR (Montrer MLXIP Anticorps)-138 function.
Data indicate that thioesterases APT1 (Montrer FAS Anticorps)/APT2 (Montrer TAP2 Anticorps) depalmitoylate nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2 (Montrer NMNAT2 Anticorps)) and zDHHC17 (Montrer ZDHHC17 Anticorps) is the strongest candidate palmitoyltransferase for NMNAT2 (Montrer NMNAT2 Anticorps).
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms. The use of alternate polyadenylation sites has been found for this gene. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet.
acyl-protein thioesterase 1
, lysoPLA I
, lysophospholipid-specific lysophospholipase
, lysophopholipase 1
, lysophospholipase I
, phospholipase 1a
, lysophospholipase 1
, calcium-independent phospholipase A2