anti-Lysyl Oxidase (LOX) Anticorps

The protein encoded by LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin.

afficher tous les anticorps Gène GeneID UniProt
Anti-Humain LOX LOX 4015 P28300
Anti-Souris LOX LOX 16948 P28301
Anti-Rat LOX LOX 24914 P16636
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Top anti-LOX Anticorps sur anticorps-enligne.fr

Showing 10 out of 189 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué ICC, IF, IHC, IHC (p), SimWes, WB Immunohistochemistry: LOX Antibody [ABIN250966] - Human placental villi, 40X. Staining of placental trophoblasts using ABIN250966 at 10 ug/ml. Detection of LOX in mouse kidney lysate using ABIN250966 (1:1,000). ECL detection was 15 sec. 0.05 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails
Humain Souris Inconjugué FACS, IF, IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Lapin Inconjugué ICC, IHC (fro), IF, IHC (p), IHC, WB Staining of LOX in mouse spleen using ABIN258622. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), IHC, WB Staining of LOPP in mouse intestine using ABIN258371. Western Blot: LOX propeptide Antibody [ABIN2583718] - Detection of LOPP in MC3T3-E1 cell lysate. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails
Humain Souris Inconjugué IF, IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Lapin Inconjugué FACS, ICC, IF, IP, SimWes, WB Flow Cytometry: LOX propeptide Antibody [NBP1-30327] - Staining of NTERA-2 cells using NP1-30327 at a 1:200 dilution detected using Dylight-488 conjugated goat anti-rabbit IgG secondary antibody. Immunocytochemistry/Immunofluorescence: LOX propeptide Antibody [NBP1-30327] - Staining in Hela cells detected with a Dylight 488 labeled secondary antibody (Green) with Hoechst 33258 nuclear counterstain (Blue). 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$415.44
Détails
Humain Lapin Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Souris Inconjugué FACS, IF, WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Lapin Inconjugué ICC, IF, WB Western Blot: LOX Antibody [ABIN4331347] - Analysis of LOX in human kidney Immunocytochemistry/Immunofluorescence: LOX Antibody [ABIN4331347] - LOX antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), SimWes, WB Simple Western: LOX Antibody [ABIN4331341] - Simple Western lane view shows a specific band detected for LOX in HeLa lysate. This experiment was performed under reducing conditions using the Wes or Sally Sue separation system 12-230kDa (or 66-440kDa). Simple Western: LOX Antibody [ABIN4331341] - Simple Western lane view shows a specific band for LOX in 1.0 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230kDa separation system. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$514.63
Détails

anti-LOX Anticorps mieux référencés

  1. Human Polyclonal LOX Primary Antibody pour ICC, IF - ABIN4331341 : Ovchinnikova, Robertson, Wågsäter, Folco, Hyry, Myllyharju, Eriksson, Libby, Hansson: T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. dans The American journal of pathology 2009 (PubMed)
    Show all 17 Pubmed References

  2. Cow (Bovine) Polyclonal LOX Primary Antibody pour ICC, IF - ABIN4331351 : Atsawasuwan, Mochida, Katafuchi, Kaku, Fong, Csiszar, Yamauchi: Lysyl oxidase binds transforming growth factor-beta and regulates its signaling via amine oxidase activity. dans The Journal of biological chemistry 2008 (PubMed)
    Show all 14 Pubmed References

  3. Cow (Bovine) Polyclonal LOX Primary Antibody pour ICC, IF - ABIN250966 : Wilhelmus, Bol, van Duinen, Drukarch: Extracellular matrix modulator lysyl oxidase colocalizes with amyloid-beta pathology in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis--Dutch type. dans Experimental gerontology 2013 (PubMed)
    Show all 10 Pubmed References

  4. Human Polyclonal LOX Primary Antibody pour ICC, IHC (fro) - ABIN258622 : Jeay, Pianetti, Kagan, Sonenshein: Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B. dans Molecular and cellular biology 2003 (PubMed)
    Show all 9 Pubmed References

  5. Human Polyclonal LOX Primary Antibody pour ICC, IF - ABIN258371 : Palamakumbura, Jeay, Guo, Pischon, Sommer, Sonenshein, Trackman: The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells. dans The Journal of biological chemistry 2004 (PubMed)
    Show all 5 Pubmed References

  6. Human Polyclonal LOX Primary Antibody pour FACS, ICC - ABIN447477 : Sato, Trackman, Mäki, Myllyharju, Kirsch, Sonenshein: The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells. dans Molecular and cellular biology 2011 (PubMed)
    Show all 4 Pubmed References

  7. Human Polyclonal LOX Primary Antibody pour ICC, IF - ABIN440592 : Di Stefano, Torsello, Bianchi, Cifola, Mangano, Bovo, Cassina, De Marco, Corti, Meregalli, Bombelli, Viganò, Battaglia, Strada, Perego: Major Action of Endogenous Lysyl Oxidase in Clear Cell Renal Cell Carcinoma Progression and Collagen Stiffness Revealed by Primary Cell Cultures. dans The American journal of pathology 2016 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal LOX Primary Antibody pour WB - ABIN1882261 : Gao, Xiao, Ma, Li, Liu, Feng, Fang, Wu, Han, Zhang, Sun, Wu, Padera, Chen, Wong, Ge, Ji: LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling. dans Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 3 Pubmed References

  9. Human Monoclonal LOX Primary Antibody pour WB - ABIN1882262 : Santhanam, Baker, Hegamyer, Kirschmann, Colburn: Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion. dans Oncogene 2010 (PubMed)
    Show all 3 Pubmed References

  10. Human Polyclonal LOX Primary Antibody pour ICC, IF - ABIN4331347 : Contente, Yeh, Friedman: Tumor suppressive effect of lysyl oxidase proenzyme. dans Biochimica et biophysica acta 2009 (PubMed)

Plus d’anticorps contre LOX partenaires d’interaction

Zebrafish Lysyl Oxidase (LOX) interaction partners

  1. Partial knockdown of lysyl oxidase genes sensitizes the developing embryo to dithiocarbamate exposure.

  2. Data reveal a role for lysyl oxidase in early morphogenesis, especially in muscle development and neurogenesis, and resume some aspects of physiopathology of copper metabolism.

Human Lysyl Oxidase (LOX) interaction partners

  1. this study has revealed that IL-1beta (Montrer IL1B Anticorps) may contribute to the rupture of fetal membranes by attenuating collagen crosslinking through downregulation of LOX expression in amnion fibroblasts

  2. This study focused on the relationship between lysyl oxidase (LOX), LOX-like protein 1 (LOXL1 (Montrer LOXL1 Anticorps)), and LOXL2 (Montrer LOXL2 Anticorps) and pulmonary emphysema pathogenesis.

  3. The aim was to examine if the serum concentrations of elastin (Montrer ELN Anticorps)-related proteins correlate to signs of cardiovascular diseases in patients with Diabetes mellitus type 2.

  4. LOX role in cancer stromal cells activation and promotion of gastric cancer progression

  5. an association of LOX gene polymorphism (G473A) on diabetes and DFU patients

  6. LOX expression was mildly but significantly upregulated in CD34 (Montrer CD34 Anticorps)+-derived primary myelofibrosis megakaryocytes and platelets compared with controls. These megakaryocytes showed a greater tendency to adhere and spread to monomeric collagen, and this was inhibited by the LOX-specific inhibitor BAPN (Montrer ANPEP Anticorps).

  7. Data suggest that a missense mutation in lysyl oxidase (LOX) is associated with aortic disease.

  8. Our findings suggest that LOX has a role in cancer cell mitosis

  9. Our findings provide new evidence that LOX regulates SNAI2 expression and that SNAI2-mediated TIMP4 (Montrer TIMP4 Anticorps) secretion plays a role in cancer progression.

  10. UXT (Montrer UXT Anticorps) Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha (Montrer ESR1 Anticorps) Activity in Breast Cancer Cells.

Pig (Porcine) Lysyl Oxidase (LOX) interaction partners

  1. Statins normalize vascular lysyl oxidase (LOX) down-regulation induced by proatherogenic risk factors.

Cow (Bovine) Lysyl Oxidase (LOX) interaction partners

  1. These results indicate that proLOX could be processed by two different mechanisms producing two forms of active LOX.

  2. Lysyl oxidase enhances elastin (Montrer ELN Anticorps) synthesis and matrix formation by vascular smooth muscle cells

  3. Lysyl oxidase has a role in oxidizing basic fibroblast growth factor (Montrer FGF2 Anticorps) and inactivating its mitogenic potential

  4. In cases of vascular calcification, the decreased expression of LOX may be partially responsible for decreased vascular elasticity and also for the decreased formation of new elastic fibers.

  5. Statins normalize vascular lysyl oxidase down-regulation induced by proatherogenic risk factors.

Mouse (Murine) Lysyl Oxidase (LOX) interaction partners

  1. LOX up-regulation is associated with enhanced oxidative stress that promotes p38MAPK (Montrer MAPK14 Anticorps) activation, elastin (Montrer ELN Anticorps) structural alterations, and vascular stiffness.

  2. These results suggest that LOX has the ability to induce RANKL (Montrer TNFSF11 Anticorps) expression on stromal cells; however, it fails to substitute for RANKL (Montrer TNFSF11 Anticorps) in osteoclastogenesis.

  3. UXT (Montrer UXT Anticorps) Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha (Montrer ESR1 Anticorps) Activity in Breast Cancer Cells.

  4. Data show that LOX-PP enhances adipogenesis at least partially through inhibition of FGF-2 (Montrer FGF2 Anticorps) receptor signaling.

  5. LOX targeting reduces peritoneal fibrosis.

  6. Absence of lysyl oxidase (Lox) causes thoracic aortic aneurysms. The aortic mechanical behavior of Lox(-/-) mice is consistent with reduced elastin (Montrer ELN Anticorps) and collagen cross-linking but demonstrates vascular location-specific differences. Lox(-/-) aortas show upregulation of matrix remodeling genes and location-specific differential expression of other matrix and smooth muscle cell gene sets.

  7. Findings from this study indicate that preventing LOX overexpression may be protective against high glucose-induced apoptosis in retinal vascular cells associated with diabetic retinopathy.

  8. LOX family members contribute significantly to the detrimental effects of cardiac remodelling, highlighting LOX inhibition as a potential therapeutic strategy for post-infarction recovery

  9. Findings suggest that the lysyl oxidase (LOX)-mediated organization of collagen fibers in the extracellular matrix is an important regulator of osteoblastogenesis.

  10. The data suggest a fibromodulin (Montrer FMOD Anticorps)-modulated collagen cross-linking mechanism where fibromodulin (Montrer FMOD Anticorps) binds to a specific part of the collagen domain and also forms a complex with lysyl oxidase, targeting the enzyme toward specific cross-linking sites.

LOX profil antigène

Profil protéine

The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Lysyl Oxidase (LOX) Anticorps

  • lysyl oxidase (LOX) anticorps
  • lysyl oxidase (lox) anticorps
  • lysyl oxidase a (loxa) anticorps
  • lysyl oxidase L homeolog (lox.L) anticorps
  • lysyl oxidase (Lox) anticorps
  • AI893619 anticorps
  • H-rev142 anticorps
  • lox anticorps
  • MGC146507 anticorps
  • Rrg1 anticorps
  • TSC-160 anticorps
  • Xlox anticorps
  • zgc:77447 anticorps

Protein level used designations for anti-Lysyl Oxidase (LOX) Anticorps

lysyl oxidase , protein-lysine 6-oxidase-like , protein-lysine 6-oxidase , ras excision protein , ras recision gene (rrg) , Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts)

GENE ID SPECIES
471614 Pan troglodytes
699997 Macaca mulatta
780067 Xenopus (Silurana) tropicalis
100189621 Oncorhynchus mykiss
100457685 Pongo abelii
404621 Danio rerio
734204 Xenopus laevis
4015 Homo sapiens
100525278 Sus scrofa
280841 Bos taurus
16948 Mus musculus
24914 Rattus norvegicus
396474 Gallus gallus
481478 Canis lupus familiaris
100720740 Cavia porcellus
100357045 Oryctolagus cuniculus
101112220 Ovis aries
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