Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
MXD4 is a member of the MAD gene family . De plus, nous expédions MAX Dimerization Protein 4 Anticorps (39) et beaucoup plus de produits pour cette protéine.
Showing 5 out of 5 products:
The E3 ligase activity of c-IAP1 was not required for downregulation of Mad4 expression.
regulation by a transcriptional repressor complex that contains Miz-1 and c-Myc
Data suggest that the biological function of the interaction between T-complex protein 10-like and MAD4 may be to maintain the differentiation state in liver cells.
replicative senescence-specific factors may block c-Myc inhibition of Miz-1 activation of hMad4 expression, and the continual presence of hMad4 protein may transcriptionally repress selected c-Myc target genes
during embryonic hematopoietic differentiation Mxd4 is an important player in the regulation of blood progenitor proliferation, and downregulation of its expression might be required for a proliferative burst preceding lineage specification.
Mxd4 and Mnt upregulation following OX40 engagement most likely increases T-cell survival
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
, class C basic helix-loop-helix protein 12
, max dimerization protein 4
, max dimerizer 4
, max-associated protein 4
, max-interacting transcriptional repressor MAD4
, MAX dimerization protein 4
, basic helix-loop-helix transcription factor XMad4-236
, putative basic helix-loop-helix transcription factor variant 3