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MAEA product mediates the attachment of erythroblasts to macrophages. De plus, nous expédions MAEA Protéines (16) et MAEA Kits (9) et beaucoup plus de produits pour cette protéine.
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Emp expression correlates with erythroblastic island formation and has an important function for bone marrow hematopoiesis.
These results suggest that Emp undergoes dynamic rearrangements within the nuclear architecture that are correlated with cell division.
RanBPM, ARMC8alpha, ARMC8beta, Muskelin, p48EMLP, and p44CTLH form complexes in cells.
results implicate Emp in abnormal cell motility in macrophage cells
Emp null model provides an experimental system to study enucleation process and to evaluate the function of macrophages in definitive erythropoiesis.
Temporal and spatial expression of Emp correlates with its role in erythroblastic island formation, suggesting that Emp may be involved in multiple cellular functions.
Emp plays a cell intrinsic role in the erythroid lineage
This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes\; this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
macrophage erythroblast attacher
, GID complex subunit 9, FYV10 homolog
, cell proliferation-inducing gene 5 protein
, erythroblast macrophage protein
, human lung cancer oncogene 10 protein
, lung cancer-related protein 10
, proliferation-inducing gene 5