anti-Major Facilitator Superfamily Domain Containing 8 (MFSD8) Anticorps

MFSD8 encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. De plus, nous expédions et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MFSD8 256471 Q8NHS3
MFSD8 72175 Q8BH31
MFSD8    
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-Major Facilitator Superfamily Domain Containing 8 Anticorps sur anticorps-enligne.fr

Showing 10 out of 11 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-MFSD8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate WB Suggested Anti-MFSD8  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: HepG2 cell lysate 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, WB   100 μL 11 to 13 Days
$335.04
Détails
Humain Lapin Inconjugué IF, IHC (p), WB Immunofluorescent staining of human cell line U-251 MG with MFSD8 polyclonal antibody  at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and vesicles. Immunohistochemical staining of human kidney with MFSD8 polyclonal antibody  shows distinct cytoplasmic and membranous positivity in cells in tubules at 1:50-1:200 dilution. 100 μL 11 to 12 Days
$577.33
Détails
Humain Lapin Inconjugué WB Western Blot showing MFSD8 antibody used at a concentration of 1-2 ug/ml to detect its target protein. 50 μg 9 to 11 Days
$449.29
Détails
Humain Lapin Inconjugué ELISA, IHC, WB   100 μg 13 to 16 Days
$407.69
Détails
Humain Lapin Biotin ELISA   100 μg 11 to 18 Days
$469.05
Détails
Humain Lapin FITC ELISA   100 μg 11 to 18 Days
$469.05
Détails
Humain Lapin HRP ELISA   100 μg 11 to 18 Days
$469.05
Détails
Humain Lapin Inconjugué ELISA, IF/ICC, IHC   100 μg 11 to 18 Days
$469.05
Détails

Plus d’anticorps contre Major Facilitator Superfamily Domain Containing 8 partenaires d’interaction

Human Major Facilitator Superfamily Domain Containing 8 (MFSD8) interaction partners

  1. We identified a novel homozygous mutation in MFSD8 gene.

  2. Quantification revealed that the amounts of 12 different soluble lysosomal proteins were significantly reduced in Cln7 ko MEFs compared with wild-type controls. One of the most significantly depleted lysosomal proteins was Cln5 protein that underlies another distinct neuronal ceroid lipofuscinosis disorder

  3. This study highlights a hierarchy of MFSD8 variant severity, predicting three consequences of mutation: (1) nonsyndromic localized maculopathy, (2) nonsyndromic widespread retinopathy, or (3) syndromic neurological disease.

  4. MFSD8 genetic testing should also be considered in patients with Rett like phenotype at onset and negative MECP2 mutation

  5. A mutation in MFSD8, c.472G>A (p.Gly158Ser), segregates with the disease phenotype in variant late infantile neuronal ceroid lipofuscinosis.

  6. In this study, we identified variants in MFSD8 as a novel cause of nonsyndromic autosomal recessive macular dystrophy with central cone involvement.

  7. This study showed that Gene disruption of Mfsd8 provides animal model for CLN7 disease.

  8. Expression and lysosomal targeting of CLN7 are reported.

  9. MFSD8 gene is involved in late-infantile-onset neuronal ceroid lipofuscinose;it was mapped to chromosome 4q28.1-q28.2.

  10. Results describe a novel mutation in the MFSD8 gene, responsible for neuronal ceroid lipofuscinoses, in a consanguineous Egyptian family

  11. Study contributes to a better molecular characterization of Italian NCL cases, and will facilitate medical genetic counseling in such families.

  12. CLN7/MFSD8 defects are not restricted to the Turkish population, as initially anticipated, but are a relatively common cause of NCL in different populations.

  13. Data show that neuronal ceroid lipofuscinosis in a Saudi family is due to a homozygous novel mutation in the most recently described NCL gene (MFSD8).

Mouse (Murine) Major Facilitator Superfamily Domain Containing 8 (MFSD8) interaction partners

  1. Our data demonstrate for the first time that the putative lysosomal transporter CLN7 is relevant for lysosome motility and plays an important role for neuronal cell survival under conditions of starvation.

  2. Quantification revealed that the amounts of 12 different soluble lysosomal proteins were significantly reduced in Cln7 ko MEFs compared with wild-type controls. One of the most significantly depleted lysosomal proteins was Cln5 protein that underlies another distinct neuronal ceroid lipofuscinosis disorder

  3. We have disrupted the Cln7/Mfsd8 gene in mice by targeted deletion of exon 2 generating a novel knockout (KO) mouse model for CLN7 disease, which recapitulates key features of human CLN7 disease pathology.

Major Facilitator Superfamily Domain Containing 8 (MFSD8) profil antigène

Profil protéine

This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL).

Gene names and symbols associated with MFSD8

  • major facilitator superfamily domain containing 8 (MFSD8) anticorps
  • major facilitator superfamily domain containing 8 (Mfsd8) anticorps
  • major facilitator superfamily domain containing 8 L homeolog (mfsd8.L) anticorps
  • 2810423E13Rik anticorps
  • AI836898 anticorps
  • AV142426 anticorps
  • Cln7 anticorps

Protein level used designations for MFSD8

ceroid-lipofuscinosis neuronal protein 7 , ceroid-lipofuscinosis, neuronal 7, late infantile , major facilitator superfamily domain-containing protein 8

GENE ID SPECIES
256471 Homo sapiens
72175 Mus musculus
444062 Xenopus laevis
Fournisseurs de qualité sélectionnés pour anti-Major Facilitator Superfamily Domain Containing 8 (MFSD8) Anticorps
Avez-vous cherché autre chose?