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The protein encoded by MCTS1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. De plus, nous expédions Malignant T Cell Amplified Sequence 1 Kits (11) et Malignant T Cell Amplified Sequence 1 Protéines (10) et beaucoup plus de produits pour cette protéine.
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Mouse (Murine) Polyclonal MCTS1 Primary Antibody pour IHC - ABIN966547
Carpenter, Poole, Halestrap: Cloning and sequencing of the monocarboxylate transporter from mouse Ehrlich Lettré tumour cell confirms its identity as MCT1 and demonstrates that glycosylation is not required for MCT1 function. dans Biochimica et biophysica acta 1996
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Human Polyclonal MCTS1 Primary Antibody pour WB - ABIN4891880
Haas, Ngo, Li, Schleich, Qu, Vanyai, Cullen, Cardona-Alberich, Gladwyn-Ng, Pagnamenta, Taylor, Stewart, Kini, Duncan, Teleman, Keays, Heng: De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation. dans Cell reports 2016
Human Polyclonal MCTS1 Primary Antibody pour WB - ABIN152954
Kumar, Kant, Singh et al.: Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage ... dans Toxicology and applied pharmacology 2013
DENR (Montrer DENR Anticorps) binds to the P-site of the 40S ribosomal subunit and together with MCTS1 forms a tRNA binding surface and interferes with eIF1 (Montrer EIF1 Anticorps)/eIF2 (Montrer EIF2S1 Anticorps)/eIF3 (Montrer EIF3A Anticorps) binding, thus operating in post-termination ribosome recycling and translation re-initiation
Reinitiation complexes involving initiation factors eIF2D (Montrer EIF2D Anticorps), MCT-1 (Montrer CMA1 Anticorps), and DENR (Montrer DENR Anticorps) controls the translation of a large fraction of mammalian cellular mRNAs.
Overexpression of MCT1 (Montrer CMA1 Anticorps) is associated with gliomas.
MCT-1 (Montrer CMA1 Anticorps) is a new centrosomal-associated oncoprotein, and that it plays a novel role in the regulation of mitosis signifies its important function in the process of tumorigenesis.
The present study indicates possible involvement of a protein kinase (Montrer CDK7 Anticorps) (PK)C- and PKA-mediated pathway associated with expression of MCT1 (Montrer CMA1 Anticorps) and lactate transport in rhabdomyosarcoma cells.
The oppositions between MCT-1 (Montrer CMA1 Anticorps) and p53 (Montrer TP53 Anticorps) are firstly confirmed at multistage processes that include transcription control, mRNA metabolism, and protein expression
The result suggest that co-expression of CD147 and MCT1 (Montrer CMA1 Anticorps)/MCT4 (Montrer SLC16A4 Anticorps) is related to drug resistance during EOC metastasis and could be useful therapeutic targets to prevent the development of incurable, recurrent and drug resistance EOC.
Results describe the expression and purification of MCT-1 (Montrer CMA1 Anticorps) in insect cells using a baculovirus expression system.
tumor cell lines overexpressing MCT-1 (Montrer CMA1 Anticorps) exhibited increased growth rates and displayed increased protection against apoptosis induced by serum starvation
demonstrated the presence of sequence-specific DNA-binding protein (Montrer UBE2V1 Anticorps) in nuclear extracts designated as LMBF; the 26-mer (Montrer MERTK Anticorps) oligonucleotide containing the LMBF binding site is required for maximum transcriptional activity of the MCT-1 (Montrer CMA1 Anticorps) promoter
Data suggest that expression of MCT1 in intestinal mucosa can be altered by diet; here, expression of MCT1 is down-regulated in colonic mucosa by high-protein diet and appears to be linked to fermentation of dietary proteins by intestinal microbes.
MCT1-mRNA showed a higher expression in the ileum; feeding inulin-coated butyrate resulted in an increased ileal surface; delivery of butyrate to the colon requires a more resistant inulin-coating.
The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.
malignant T cell-amplified sequence 1
, malignant T-cell-amplified sequence 1
, multiple copies T-cell malignancies
, multiple copies T-cell malignancies 1
, malignant T cell amplified sequence 1
, Malignant T cell amplified sequence 1-A
, malignant T cell-amplified sequence 1-A
, malignant T-cell-amplified sequence 1-A