anti-Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10) Anticorps

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. De plus, nous expédions Matrix Metallopeptidase 10 (Stromelysin 2) Kits (57) et Matrix Metallopeptidase 10 (Stromelysin 2) Protéines (15) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MMP10 4319 P09238
MMP10 17384 O55123
MMP10 117061 P07152
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Top anti-Matrix Metallopeptidase 10 (Stromelysin 2) Anticorps sur anticorps-enligne.fr

Showing 10 out of 166 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué WB 100 μg 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué WB WB Suggested Anti-MMAntibody Titration:  2.5ug/ml  Positive Control:  Jurkat cell lysate 100 μL 2 to 3 Days
$229.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of MMP10 expression in HepG2 (A), NIH3T3 (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IC, FACS, IF, IHC, WB Immunofluorescent analysis of MMP10 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MMP10 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, IHC (p), WB Western blot analysis of MMP10 using anti-MMP10 antibody (A03759). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: rat cardiac muscle tissue lysates, Lane 2: mouse cardiac muscle tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-MMP10 antigen affinity purified polyclonal antibody (Catalog # A03759) at 0.5 ug/mL overnight at 4℃, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for MMP10 at approximately 54KD. The expected band size for MMP10 is at 54KD. IHC analysis of MMP10 using anti-MMP10 antibody (A03759).MMP10 was detected in paraffin-embedded section of human colon cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1ug/ml rabbit anti-MMP10 Antibody (A03759) overnight at 4℃. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37℃. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using MMP-10 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using MMP-10 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué EIA, IHC (p) 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, WB Western Blot (WB) analysis of specific cells using Cleaved-MMP-10 (F99) Polyclonal Antibody. 100 μL Disponible
$363.46
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, IHC (p) 100 μL 11 to 14 Days
$493.17
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, WB Western blot analysis of extracts of HepG2, using MMP10antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277407 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600 was used as secondary antibod 100 μL 11 to 12 Days
$390.77
Détails

anti-Matrix Metallopeptidase 10 (Stromelysin 2) Anticorps mieux référencés

  1. Human Polyclonal MMP10 Primary Antibody pour WB - ABIN966586 : Muller, Quantin, Gesnel, Millon-Collard, Abecassis, Breathnach: The collagenase gene family in humans consists of at least four members. dans The Biochemical journal 1988 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal MMP10 Primary Antibody pour IF, IHC - ABIN6712088 : Zhang, Shen, Zhang, Wan, Yao, Wu, Wang, Chen, Yan, Jiang: Induction of thoracic aortic remodeling by endothelial-specific deletion of microRNA-21 in mice. dans PLoS ONE 2013 (PubMed)

  3. Human Polyclonal MMP10 Primary Antibody pour WB - ABIN517967 : Teng, Wang, Hood, Conrads, Hamilton, Maxwell, Darcy, Conrads: Identification of candidate circulating cisplatin-resistant biomarkers from epithelial ovarian carcinoma cell secretomes. dans British journal of cancer 2014 (PubMed)

Plus d’anticorps contre Matrix Metallopeptidase 10 (Stromelysin 2) partenaires d’interaction

Human Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10) interaction partners

  1. increased abundance of Snail and Axin2 is highly correlated to malignant transformation of OL, making them novel biomarker(s) predicting oral cancer development

  2. MMP10, either alone or in combination with tPA, might represent a new strategy for thrombolysis in ischemic stroke, providing higher protection against cerebrovascular damage.

  3. There is a significant association in the expression of P-Rex1 and MMP10 in human luminal breast cancer, and their co-expression is indicative of poor prognosis.

  4. MMP10 is a novel marker for cancer stem-like cells (CSCs)/cancer-initiating cells in epithelial ovarian cancer

  5. Data show that AJUBA upregulated MMP10 and MMP13 expression in esophageal squamous cell carcinoma (ESCC).

  6. MMP10 is overexpressed in the serum and pulmonary arteries of patients with systemic sclerosis-associated pulmonary hypertension.

  7. Using a quantum chemical approach method, it has been established that mutations in MMP-10 and FGA proteins led to substantial energetic modifications suggesting an impact on their functions and/or stability in the recurrent pregnancy loss patients.

  8. These results indicate that MMP10 serves a beneficial role in response to acute infection by moderating the proinflammatory response of resident and infiltrating macrophages.

  9. We conclude that in the resected esophageal cancer an increased mRNA expression of MMP-7, MMP-10 and TIMP-1 correlated with clinicopathologic features. We suggest that these genes may play a role during progression of the disease MMP-10, MMP-7, TIMP-1, TIMP-2 were overexpressed in 73%, 85%, 55% and 42% of esophageal cancer samples, respectively.

  10. Mycobacterium tuberculosis activates inflammatory and stromal cells to secrete MMP-10, and this is partly driven by the virulence factor early secretory antigenic target-6.

  11. MMP10 expression is significantly upregulated in human masticatory mucosa during wound healing.

  12. Our results suggest that the level of the MMP-10 expression in tumor epithelium of cutaneous squamous cell carcinoma and basal cell carcinoma may contribute to the different invasive patterns observed in these tumors

  13. these results suggest that TGF-beta1 stimulates HSC-4 cell invasion through the Slug/Wnt-5b/MMP-10 signalling axis.

  14. the rs17435959 polymorphism of the MMP-10 gene may be associated with an increased risk of pelvic organ prolapse (POP).

  15. According to this study, the expression of ST-2 is associated with histopathological grade and tumor differentiation in head and neck squamous cell carcinomas.

  16. MMP-10 may be a novel biomarker reflecting both disease severity and prognosis in patients with idiopathic pulmonary fibrosis.

  17. Noncomplicated PVVs are associated with systemic, prothrombotic activation of hemostasis and increased concentration of MMP-10, suggesting a prothrombotic and proinflammatory state.

  18. Up-regulation of matrix metalloproteinase 10 is associated with colitis-associated cancer.

  19. hepatocellular carcinoma cells stably expressing MMP10 had increased CXCR4 expression and migratory capacity

  20. No association was found between MMP10 C/T rs486055 variants and anterior cruciate ligament rupture.

Mouse (Murine) Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10) interaction partners

  1. These results indicate that MMP10 serves a beneficial role in response to acute infection by moderating the proinflammatory response of resident and infiltrating macrophages.

  2. MMP-10 facilitates the clearance of multiwalled carbon nanotubesand moderates the pro-inflammatory response of exposed alveolar and infiltrated macrophages.

  3. crosstalk between MMP10 and the CXCR4/SDF1 axis contributes to hepatocarcinogenesis

  4. Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair.

  5. our findings support a model in which MMP-10 activity modulates CXCR4/SDF1 signaling, which is essential for efficient skeletal muscle regeneration.

  6. Dissection of the matrix metalloproteinase 10 (MMP10) substrate degradome in fibroblast secretomes.

  7. Thus, our findings indicate that MMP-10 is critical for skeletal muscle maintenance and regeneration during injury and disease.

  8. MMP10 promotes macrophage movement

  9. Assessed MMP-10's role in a murine model of colonic tissue damage induced by dextran sulfate sodium(DSS) treatment, and conclude MMP10 is required for resolution of DSS-induced colonic damage, and in its absence, chronic inflammation and dysplasia occurs.

  10. Mmp10 is required for maintenance of a highly tumorigenic, cancer-initiating, metastatic stem-like cell population in lung cancer.

  11. MMP-10 was capable of enhancing tissue plasminogen activator-induced fibrinolysis via a thrombin-activatable fibrinolysis inhibitor inactivation-mediated mechanism.

  12. Data show that S100a9, Mmp10 and Ang2 were among the most downregulated genes, whereas Per3, Tef and Prdx6 were significantly upregulated in the DMH + Calcium group.

  13. Mmp10 is overexpressed in lung tumors induced by either the smoke carcinogen urethane or oncogenic Kras.

  14. These findings support the hypothesis that CHF1/Hey2 is an important regulator of MMP10 expression.

  15. Data demonstrate induction of MMP-10 by VEGF in HUVEC and support an angiogenic role for MMP-10 in response to VEGF stimulation in vitro and in vivo.

  16. This study examined the hypothesis that the control of NADPH oxidase-2 (Nox2)-mediated reactive oxygen species (ROS) regulates the expression of matrix metalloproteinases (MMPs) and the migration of macrophages.

  17. Results suggest that MMP-10 may be important in the initial stages of squamous cell cancer progression and induced in the stroma relating to the general host-response reaction to skin cancer.

  18. TGF-beta transcriptionally upregulated MMP-10 through activation of MEF2A, concomitant with acetylation of core histones increasing around the promoter, as a consequence of degradation of the class IIa HDACs.

  19. Mice injected with lymphoma cells constitutively expressing MMP10 develop thymic lymphoma more rapidly than those injected with control lymphoma cells.

  20. a tightly regulated expression level of stromelysin-2 is required for limited matrix degradation at the wound site

Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10) profil antigène

Profil protéine

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene names and symbols associated with MMP10

  • matrix metallopeptidase 10 (MMP10) anticorps
  • matrix metallopeptidase 10 (Mmp10) anticorps
  • AV377895 anticorps
  • MMP-10 anticorps
  • SL-2 anticorps
  • STMY2 anticorps

Protein level used designations for MMP10

MMP-10 , matrix metalloprotease 10 , matrix metalloproteinase 10 (stromelysin 2) , matrix metalloproteinase-10 , stromelysin 2 , stromelysin-2 , transin 2 , transin-2 , matrix metalloproteinase 10 , SL-2 , transformation-associated protein 34A

GENE ID SPECIES
4319 Homo sapiens
17384 Mus musculus
117061 Rattus norvegicus
100101603 Oryctolagus cuniculus
100727690 Cavia porcellus
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