Matrix Metallopeptidase 15 (Membrane-inserted) Protéines (MMP15)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. De plus, nous expédions MMP15 Anticorps (108) et MMP15 Kits (9) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
MMP15 17388 O54732
Rat MMP15 MMP15 291848  
MMP15 4324 P51511
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Top MMP15 Protéines sur anticorps-enligne.fr

Showing 8 out of 11 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Escherichia coli (E. coli) Humain Inconjugué 10 μg 6 to 7 Days
$474.41
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg 50 to 55 Days
$7,493.38
Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg 50 to 55 Days
$5,262.31
Détails
Escherichia coli (E. coli) Souris His tag,T7 tag 100 μg 15 to 18 Days
$752.00
Détails
Escherichia coli (E. coli) Humain Inconjugué   200 μg 6 to 7 Days
$6,938.01
Détails
Escherichia coli (E. coli) Humain Inconjugué 10 μg 11 to 12 Days
$613.33
Détails
Escherichia coli (E. coli) Humain Inconjugué 100 μg 13 to 16 Days
$698.00
Détails
Escherichia coli (E. coli) Porc Inconjugué   1 mg 11 to 18 Days
$2,046.74
Détails

MMP15 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine) ,
, ,
Human ,
,

Plus protéines pour Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15) partenaires d'interaction

Mouse (Murine) Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15) interaction partners

  1. Although neither proteinase is required for branching morphogenesis, transcriptome profiling reveals a key role for MMP14 and MMP15 in regulating mammary gland adipocyte differentiation. Whereas MMP14 promotes the generation of white fat depots crucial for energy storage, MMP15 differentially controls the formation of thermogenic brown fat.

  2. Data indicate that Snai1 is sufficient to promote mmp15 expression, cell transformation, and mesenchymal cell migration and invasion.

Human Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15) interaction partners

  1. Over-expression of MAFG-AS1 significantly decreased the level of miR-339-5p in NSCLC cell. Moreover, the matrix metalloproteinase 15 (MMP15) was identified to be a target of miR-339-5p.

  2. identify an MT2-MMP-E-cadherin axis that functions as a novel regulator of epithelial cell homeostasis in vivo

  3. Results suggest that MT2-MMP degrades adherens and tight junction proteins and results in EMT, making it a potential mediator of EMT in carcinomas.

  4. TCF-4 is a co-activator of NF-kappaB p65 that promotes MMP-15 transcription and potentiate the migration activity of the lung cancer cells

  5. In conclusion, MT2-MMP is involved in gastric cancer invasion and metastasis and may serve as an independent prognostic factor for gastric cancer patients.

  6. our data suggest that MT2-MMP expression positively involves in non-small cell lung cancer and might play an important role in promoting the tumor progression and intra-tumoral angiogenesis

  7. HLA-G expression involved in tumor invasiveness or metastasis may rely on the NK cytotoxicity inhibition and induction of MMP-15 expression in ovarian cancer.

  8. MMP-15 is up-regulated in preeclampsia, but does not cleave endoglin to produce soluble endoglin.

  9. MMP-15 and MMP-19 are upregulated during colorectal tumorigenesis

  10. Data show that MT2-MMP was a novel hypoxia-responsive gene and was upregulated by HIF-1alpha under hypoxia.

  11. The intensity of immunochemical staining of MT2-MMP was significantly positively correlated to the intratumoral angiogenesis of esophageal cancer tissues.

  12. MMP2 activity is associated with an increase in MT2-MMP expression and with lymph node metastasis.

  13. These results indicate MT2-MMP might be involved in the cancer progression more than or equal to MT1-MMP independently of MMP-2 and MT1-MMP.

  14. down-regulation of most MT-MMPs is typical for prostate carcinoma; seems to occur mainly in epithelial cells

  15. Data show that the MT2-MMP catalytic domain has a higher propensity than that of MT1-MMP to initiate cleavage of the MMP-2 prodomain in the absence of TIMP-2.

  16. Type-2 metalloproteinases, are identified as the triggering agents that independently confer cancer cells with the ability to proteolytically efface the BM scaffolding, initiate the assembly of invasive pseudopodia, and propagate transmigration.

  17. Data show that MMP15 may be relevant with carcinogenesis, development and metastasis of adenoid cystic carcinoma, and different metastasis potential may result from different subtype of MMPs gene family.

Profil protéine MMP15

Profil protéine

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily\; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.

Gene names and symbols associated with MMP15

  • matrix metallopeptidase 15 (MMP15)
  • matrix metallopeptidase 15 (Mmp15)
  • AI503551 Protéine
  • MT2-MMP Protéine
  • MTMMP2 Protéine
  • SMCP-2 Protéine

Protein level used designations for MMP15

MMP-15 , MT-MMP 2 , MT2MMP , MTMMP2 , Membrane type 2-MMP , matrix metalloproteinase 15 , matrix metalloproteinase-15 , membrane-type matrix metalloproteinase 2 , membrane-type-2 matrix metalloproteinase , matrix metalloproteinase 15 (membrane-inserted)

GENE ID SPECIES
100062872 Equus caballus
17388 Mus musculus
291848 Rattus norvegicus
4324 Homo sapiens
100514105 Sus scrofa
487257 Canis lupus familiaris
282887 Bos taurus
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