anti-Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16) Anticorps

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. De plus, nous expédions MMP16 Kits (12) et MMP16 Protéines (10) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MMP16 17389 Q9WTR0
MMP16 65205 O35548
MMP16 4325 P51512
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Top anti-MMP16 Anticorps sur anticorps-enligne.fr

Showing 10 out of 124 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué IHC (fro), IHC (p), WB Anti-MMP16 antibody, IHC(P) IHC(P): Human Rectal Cancer Tissue Anti-MMP16 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: COLO320 Cell Lysate 100 μg 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué ELISA, IHC (p), WB Western blot analysis of MMP16 using anti-MMP16 antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: mouse intestine tissue lysates, Lane 2: human SMMC-7721 whole cell lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-MMP16 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4℃, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for MMP16 at approximately 53KD. The expected band size for MMP16 is at 53KD. IHC analysis of MMP16 using anti-MMP16 antibody .MMP16 was detected in paraffin-embedded section of human colon cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1ug/ml rabbit anti-MMP16 Antibody  overnight at 4℃. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37℃. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg 4 to 6 Days
$280.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-MMAntibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  MCF7 cell lysate 100 μL 2 to 3 Days
$289.00
Détails
Poulet Lapin Inconjugué WB Western blot analysis of MMP16 expression in A431 (A), Raw264.7 (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells, using MMP-16 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MMP-16 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ELISA, IHC, WB 100 μL Disponible
$363.46
Détails
Poulet Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p) Anti-MMP16 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1103053 concentration 5 ug/ml. Anti-MMP16 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB 100 μL 11 to 14 Days
$493.17
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, IHC, WB Western blot analysis on HepG2 cell lysate using MMP16 Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6266593 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. 100 μL 11 to 12 Days
$390.77
Détails

anti-MMP16 Anticorps mieux référencés

  1. Human Polyclonal MMP16 Primary Antibody pour IHC (fro), IHC (p) - ABIN3044303 : Lin, Wang, Jie, Hong, Li, Wang, Yu: Inhibitory effects of miR-146b-5p on cell migration and invasion of pancreatic cancer by targeting MMP16. dans Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2011 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal MMP16 Primary Antibody pour ELISA, IHC (p) - ABIN5519039 : Wang, Li, Wu, Wu, Li, Yang, Chen, Xie, Huang, Du, Zhou: miR-132 can inhibit glioma cells invasion and migration by target MMP16 in vitro. dans OncoTargets and therapy 2015 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal MMP16 Primary Antibody pour WB - ABIN1883195 : Kurata, Maruyama, Kato, Sato, Yamamoto, Ozaki, Nitta, Nabeshima, Morita, Mizuno, Ito, Yuzawa, Matsuo: Tissue-type plasminogen activator deficiency attenuates peritoneal fibrosis in mice. dans American journal of physiology. Renal physiology 2009 (PubMed)

  4. Hamster Polyclonal MMP16 Primary Antibody pour IHC (p), ELISA - ABIN545708 : Nagase, Woessner: Matrix metalloproteinases. dans The Journal of biological chemistry 1999 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal MMP16 Primary Antibody pour IHC, IHC (p) - ABIN4334965 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. dans Nature methods 2013 (PubMed)

Plus d’anticorps contre MMP16 partenaires d’interaction

Mouse (Murine) Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16) interaction partners

  1. miR-155 contributed to the up-regulation of MMP-16, and MMP-16 further degraded aggrecan and collagen type II, leading to the dehydration and degeneration of intervertebral discs

  2. Neuronal knockdown of MT3-MMP resulted in the accumulation of NgR1 at the cell surface and reduced the accumulation of the NgR1 cleavage fragment in medium conditioned by cortical neurons

  3. Study demonstrates that MT3-MMP, is expressed in mesenchymal tissues of the skeleton and in peri-skeletal soft connective tissue; and MT3-MMP-deficient mice display growth inhibition tied to a decreased viability of mesenchymal cells in skeletal tissues.

Human Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16) interaction partners

  1. HOXA11-AS could promote renal cancer cells growth and invasion by modulating miR-146b-5p-MMP16 axis.

  2. Overexpression of MMP2 and MMP16 in endometrial cancerous tissues corresponded to down-regulation of miR-377, miR-382 and miR-410, while decreased expression of TIMP2 was associated with miR-200b up-regulation.

  3. MMP16 was highly expressed and correlated with poor prognosis in gastric cancer patients by promoting proliferation and invasion of gastric cancer cells

  4. Findings suggest that these MMP16 rs10090371, ADAMTS3 rs788935, TLL2 rs10882807 and MMP9 rs3918251 may be promising prognostic biomarkers for cutaneous melanoma specific survival (CMSS).

  5. the present findings indicate that MT3-MMP is down-regulated in ESCC, which correlates to lymph node metastasis and poor survival of patients with this disease.

  6. more severe intervertebral disc degeneration is correlated with higher matrix metallopeptidase 16

  7. results suggest that miR-145 functions as a tumor metastasis suppressor gene by down-regulating MMP16 and may be a potential target in osteosarcoma treatment

  8. the results support a role for MMP16 in promoting invasive properties of the meningioma tumours

  9. These results demonstrate that the MT3-MMP promoter is frequently hypermethylated in colorectal cancer and that downregulation of MT3-MMP may be important for cell migration in colorectal cancer.

  10. MMP16 is a putative indicator of adverse melanoma prognosis.

  11. Expression of MMP-16 in HTB9 and T24 cells increases following transforming growth factorbeta1 treatment.

  12. E2F1 acts as a transcriptional activator for MMPs and directly enhances MMP transcription by binding to E2F1 binding sequences in the promoter, or indirectly activates MMPs (MMP-9 and MMP-16)through enhanced Sp1 and NF-kappa B

  13. Matrix metalloproteinase 16 (MMP16) was a downstream target of miR-146b-5p.

  14. The overexpression of miR-146b-5p in glioblastoma cell lines led to MMP16 mRNA silencing, MMP2 inactivation, and the inhibition of tumour cell migration and invasion.

  15. Data show that MMP16 is regulated by miR-146a in spontaneously differentiated Caco-2 cells.

  16. MT3-MMP is a matrix-dependent modifier of the invasive tumor cell functions during melanoma progression

  17. down-regulation of most MT-MMPs is typical for prostate carcinoma; seems to occur mainly in epithelial cells

  18. Results report the structure of the catalytic domain (cd) of the membrane-type matrix metalloproteinase MT3-MMP/MMP-16 in complex with the hydroxamic acid inhibitor batimastat.

  19. MT3-MMP is not only important in matrix degradation but also may affect the function of focal adhesions through FAK cleavage.

  20. Type-3 metalloproteinases, are identified as the triggering agents that independently confer cancer cells with the ability to proteolytically efface the BM scaffolding, initiate the assembly of invasive pseudopodia, and propagate transmigration.

MMP16 profil antigène

Profil protéine

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.

Gene names and symbols associated with MMP16

  • matrix metallopeptidase 16 (Mmp16) anticorps
  • matrix metallopeptidase 16 (MMP16) anticorps
  • C8orf57 anticorps
  • MMP-X2 anticorps
  • MT-MMP2 anticorps
  • MT-MMP3 anticorps
  • Mt3-mmp anticorps
  • Mt3mmp anticorps

Protein level used designations for MMP16

MMP-16 , MT-MMP 3 , MTMMP3 , Membrane type 3-MMP , matrix metalloproteinase 16 , matrix metalloproteinase-16 , membrane-type matrix metalloproteinase 3 , membrane-type-3 matrix metalloproteinase , MT3MMP , Putative transmembrane protein C8orf57 , matrix metalloproteinase 16 (membrane-inserted) , membrane type-matrix metalloproteinase

GENE ID SPECIES
17389 Mus musculus
65205 Rattus norvegicus
4325 Homo sapiens
282886 Bos taurus
487036 Canis lupus familiaris
100153257 Sus scrofa
396116 Gallus gallus
Fournisseurs de qualité sélectionnés pour anti-MMP16 (MMP16) Anticorps
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