Megakaryocyte-Associated tyrosine Kinase Protéines (MATK)

The protein encoded by MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. De plus, nous expédions Megakaryocyte-Associated tyrosine Kinase Anticorps (123) et Megakaryocyte-Associated tyrosine Kinase Kits (8) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
MATK 4145 P42679
MATK 17179 P41242
MATK 60450 P41243
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top Megakaryocyte-Associated tyrosine Kinase Protéines sur anticorps-enligne.fr

Showing 7 out of 10 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Détails
Wheat germ Humain GST tag 10 μg 11 to 12 Days
$414.29
Détails
Escherichia coli (E. coli) Rat Inconjugué SDS-PAGE analysis of Rat MATK Protein. 100 μg 11 to 18 Days
$596.97
Détails
Levure Rat His tag   1 mg 60 to 71 Days
$3,314.67
Détails
Cellules d'insectes Humain GST tag   10 μg 3 to 4 Days
$310.00
Détails

MATK Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Rat (Rattus) ,
,

Plus protéines pour Megakaryocyte-Associated tyrosine Kinase (MATK) partenaires d'interaction

Human Megakaryocyte-Associated tyrosine Kinase (MATK) interaction partners

  1. After IGF-I stimulation, CTK is recruited to IGF-IR and its recruitment facilitates CTK's subsequent association with phospho-SHPS-1.

  2. ERBB2 binds to the SH2 domain of CHK and inhibits cell growth in human breast tumor cell lines

  3. Overexpression of the Csk homologous kinase facilitates phosphorylation of akt/protein kinase b in breast neoplasms

  4. CHK Leu223 stabilizes the movement of the alphaC-helix of the protein tyrosine kinase

  5. Loss of CHK expression is associated with human brain tumors

  6. Nuclear multi-lobulation in late S phase, which is dependent on polymerization and depolymerization of microtubules, may be involved in nuclear Chk-induced inhibition of proliferation.

  7. striking functional differences between the Csk and Chk SH2 domains and revealed functional similarities between the Chk and Src SH2 domains

  8. This study describes for the first time the Src-independent actions of CHK and provides novel insights into CHK function in neural cells.

  9. Matk/CHK is not functionally redundant with Csk, and this tyrosine kinase plays an important role as a regulator of immunologic responses

  10. Findings indicate that the importance of the N-terminal domain to Chk-induced tyrosine phosphorylation in the nucleus, and implicate that nuclear tyrosine-phosphorylated proteins may contribute to inhibition of cell proliferation.

  11. Progesterone increases MATK in mast cells and reducs cell proliferation.

  12. These results reveal a potentially important role for CHK in Src activation and tumorigenicity in colon cancer cells.

  13. CHK is capable of inhibiting the CXCL12-CXCR4 pathway in neuroblastoma.

Mouse (Murine) Megakaryocyte-Associated tyrosine Kinase (MATK) interaction partners

  1. Matk plays a critical role in bone metabolism by impairing the functions of osteoclasts and osteoblasts via distinct mechanisms involving inhibition of c-Src-dependent and -independent signaling pathways.

Cow (Bovine) Megakaryocyte-Associated tyrosine Kinase (MATK) interaction partners

  1. After IGF-I stimulation, CTK is recruited to IGF-IR and its recruitment facilitates CTK's subsequent association with phospho-SHPS-1.

Profil protéine Megakaryocyte-Associated tyrosine Kinase (MATK)

Profil protéine

The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Gene names and symbols associated with MATK

  • megakaryocyte-associated tyrosine kinase (matk)
  • megakaryocyte-associated tyrosine kinase (MATK)
  • megakaryocyte-associated tyrosine kinase (Matk)
  • zinc finger RNA binding protein 2 (ZFR2)
  • Batk Protéine
  • CHK Protéine
  • CTK Protéine
  • HHYLTK Protéine
  • HYL Protéine
  • HYLTK Protéine
  • Lsk Protéine
  • Ntk Protéine
  • si:ch211-63j24.2 Protéine

Protein level used designations for MATK

megakaryocyte-associated tyrosine kinase , megakaryocyte-associated tyrosine-protein kinase-like , CSK homologous kinase , Csk-homologous kinase , Csk-type protein tyrosine kinase , HYL tyrosine kinase , hematopoietic consensus tyrosine-lacking kinase , hydroxyaryl-protein kinase , leukocyte carboxyl-terminal src kinase related , megakaryocyte-associated tyrosine-protein kinase , protein kinase HYL , tyrosine kinase MATK , tyrosine-protein kinase CTK , tyrosylprotein kinase , Csk homologous kinase , protein kinase NTK , megakaryocyte-associated tyrosine kinase (non-receptor protein tyrosine kinase) , non-receptor protein kinase protein , protein kinase BATK , carboxyl-terminal SRC kinase homologous kinase

GENE ID SPECIES
567405 Danio rerio
769076 Gallus gallus
100477232 Ailuropoda melanoleuca
4145 Homo sapiens
17179 Mus musculus
60450 Rattus norvegicus
611999 Canis lupus familiaris
100521543 Sus scrofa
504668 Bos taurus
Fournisseurs de qualité sélectionnés pour Megakaryocyte-Associated tyrosine Kinase Protéines (MATK)
Avez-vous cherché autre chose?