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MAGEA10 is a member of the MAGEA gene family. De plus, nous expédions et et beaucoup plus de produits pour cette protéine.
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CTAs (MAGE-A4, NY-ESO-1, MAGE-A10) were more likely expressed in patients with squamous cell carcinoma of the lung and when CTAs combined with CD133, they can be better prognostic factors.
By using Molecular-Docking, 3 MAGEA10 peptides were found binding to the groove position of HLA-A( *)0210 same as MAGEA4 peptide co-crystallized with HLA-A( *)0210, which indicates they could be promising for HLA-A( *)0201 presentation in immunotherapy.
We clearly showed that MAGE-A10 is frequently expressed in the group of triple-negative breast cancer patients
High MAGE-A10 is associated with lung, skin and urothelial malignancies.
This is the first report of these MAGE-A10 alternative splice sequences, and characterization of MAGE-A expression
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.
melanoma antigen family A, 10
, MAGE-10 antigen
, cancer/testis antigen 1.10
, cancer/testis antigen family 1, member 10
, melanoma-associated antigen 10
, melanoma antigen family A, 11