anti-Melanoma Antigen Family A, 2 (MAGEA2) Anticorps

MAGEA2 is a member of the MAGEA gene family. De plus, nous expédions et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MAGEA2 17138  
MAGEA2 4101 P43356
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Showing 10 out of 51 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué WB WB Suggested Anti-MAGEA2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate WB Suggested Anti-MAGEA2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Jurkat cell lysate 100 μL 2 to 3 Days
Humain Lapin Inconjugué WB 100 μL 11 to 14 Days
Humain Lapin Inconjugué ELISA, WB Western blot analysis of MAGE2 using COLO205 whole cell lysates 100 μL 11 to 12 Days
Humain Souris Inconjugué ELISA, WB MAGEA2 monoclonal antibody (M01), clone 1H4 Western Blot analysis of MAGEA2 expression in Jurkat . Western Blot analysis of MAGEA2 expression in transfected 293T cell line by MAGEA2 monoclonal antibody (M01), clone 1H4.Lane 1: MAGEA2 transfected lysate(35 KDa).Lane 2: Non-transfected lysate. 100 μg 11 to 12 Days
Boeuf (Vache) Lapin Inconjugué WB   100 μL 2 to 3 Days
Humain Lapin Inconjugué ELISA, WB   100 μL 11 to 13 Days
Humain Lapin Inconjugué IHC (p), ELISA 50 μg 12 to 14 Days
Humain Lapin Inconjugué IHC, ELISA 0.05 mg 2 to 3 Days
Humain Lapin PE IHC, ELISA, WB   200 μL 11 to 14 Days
Humain Lapin FITC IHC, ELISA, WB   200 μL 11 to 14 Days

Plus d’anticorps contre MAGEA2 partenaires d’interaction

Human Melanoma Antigen Family A, 2 (MAGEA2) interaction partners

  1. high MAGEA2 expression is an independent prognostic factor for glioma patient poor overall survival

  2. Data indicate that melanoma-associated antigen A2 (MAGEA2)is significantly overexpressed in triple-negative breast cancer (TNBC) tissues and is important for progression of TNBC and may serve as a novel molecular therapeutic target.

  3. suppression of MAGEA2 in lung cancer cells significantly reduced the growth/survival of cancer cells. High-MAGEA2 was identified as an independent prognostic factor in lung adenocarcinoma. Specific inhibition of MAGEA2 may be a promising therapeutic strategy for patients with lung cancer.

  4. Immunohistochemistry using D2-40 monoclonal antibody (MAGE2) and anti-MITF1 increased detection of lymphovascular invasion in primary cutaneous melanoma.

  5. We find that MAGE-A2 interacts with MDM2 via the N-terminal p53-binding pocket and the RING finger domain of MDM2 that is required for homo/hetero-dimerization and for E2 ligase interaction.

  6. Consistent with increased cell death, the induced loss of MAGEA2 expression correlated with increased caspase 3/7 activity, BCL2/BAX ratio and TUNEL signal.

  7. MAGEA2 has a critical role in the development of tamoxifen-resistant breast cancer

  8. MageA2 interferes with p53 acetylation at PML-nuclear bodies (NBs) and with PMLIV-dependent activation of p53.

  9. Report MAGEA1-A6 expression in sputum suggests presence of lung cancer cells or precancerous cells.

  10. These data suggest that MAGEA2 is differentially expressed in HNSCC and functions, in part, through the p53 pathway by increasing cellular proliferation and abrogating cell cycle arrest.

  11. MAGE-A2 targets p53 transactivation function through histone deacetylase recruitment

  12. These data show, for the first time, the involvement of methyl-CpG binding domain proteins in the regulation of the MAGE-A genes.

  13. Multiple simultaneous detection of MAGE-A [subtypes] more specific and sensitive than detection of single MAGE-A antigen for the diagnostic and prognostic evaluation of oral squamous cell carcinoma

MAGEA2 profil antigène

Profil protéine

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Gene names and symbols associated with MAGEA2

  • melanoma antigen, family A, 2 (Magea2) anticorps
  • melanoma-associated antigen 2 (LOC706218) anticorps
  • MAGE family member A2 (MAGEA2) anticorps
  • CT1.2 anticorps
  • Mage-a2 anticorps
  • MAGE2 anticorps
  • MAGEA2 anticorps
  • MAGEA2A anticorps

Protein level used designations for MAGEA2

melanoma antigen family A, 2 , MAGE-2 antigen , cancer/testis antigen 1.2 , cancer/testis antigen family 1, member 2 , melanoma antigen 2 , melanoma-associated antigen 2

17138 Mus musculus
706218 Macaca mulatta
4101 Homo sapiens
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