Mex-3 Homolog C (C. Elegans) Protéines (MEX3C)

MEX3C encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. De plus, nous expédions MEX3C Anticorps (49) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
Rat MEX3C MEX3C 307271  
MEX3C 51320 Q5U5Q3
MEX3C 240396 Q05A36
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$9,797.11
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Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$9,797.11
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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MEX3C Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour Mex-3 Homolog C (C. Elegans) (MEX3C) partenaires d'interaction

Human Mex-3 Homolog C (C. Elegans) (MEX3C) interaction partners

  1. Data suggest that KH1 (Montrer KCNF1 Protéines) and HK2 (Montrer HK2 Protéines) domains of MEX3C bind with high affinity to MRE10, a 10-mer (Montrer MERTK Protéines) RNA (5prime-CAGAGUUUAG-3prime) containing an eight-nucleotide MEX3C recognition element motif (AGAGUUUA); 3prime-untranslated region of HLA-A2 mRNA contains such a high affinity binding site for KH domains of MEX3C. (MEX3C = mex-3 (Montrer MEX3D Protéines) RNA binding family member C; HLA-A2 = HLA class I (Montrer MICA Protéines) histocompatibility antigen, A-2 alpha chain (Montrer FCGRT Protéines))

  2. associates with cytoplasmic deadenylation complexes and ubiquitinates CNOT7 (Montrer CNOT7 Protéines)

  3. The RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradation

  4. In combination sibling-pair linkage analysis and case-control association studies of chromosome 18, RKHD2 is found to contribute to the genetic susceptibility of essential hypertension.

Mouse (Murine) Mex-3 Homolog C (C. Elegans) (MEX3C) interaction partners

  1. MEX3C associates with the endolysosomal compartment through an endocytosis-like process. siRNA-mediated inhibition of the MEX3C or AP-2 complex (Montrer AP2B1 Protéines) substantially decreased exosomal but not cellular microRNA miR (Montrer MLXIP Protéines)-451a expression

  2. The specific expression of this long MEX3C isoform in oocytes and its ability to enhance FOS mRNA nuclear export and stability all suggest that MEX3C(659AA) is an RNA-binding protein that preserves maternal FOS mRNA in oocytes.

  3. Data indicate that Mex3c mutation significantly increases physical activity.

  4. MEX3C is required for cytokine production after infection with RNA viruses that are detected by RIG-I (Montrer DDX58 Protéines).

  5. Mex3c mutation caused leanness in both heterozygous and homozygous transgenic mice, as well as a more beneficial blood glucose and lipid profile in homozygous transgenic mice, in both sexes; data show Mex3c is involved in energy balance regulation

  6. data suggest that MEX3C plays an important role in enhancing the translation of Igf1 (Montrer IGF1 Protéines) mRNA directly or indirectly and promoting postnatal growth

Profil protéine MEX3C

Profil protéine

This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension.

Gene names and symbols associated with MEX3C

  • mex-3 RNA binding family member C (Mex3c)
  • mex-3 RNA binding family member C (MEX3C)
  • mex-3 RNA binding family member C (mex3c)
  • mex3 RNA binding family member C (Mex3c)
  • A130001D14Rik Protéine
  • BC035207 Protéine
  • BM-013 Protéine
  • MEX-3C Protéine
  • rkhd2 Protéine
  • RNF194 Protéine

Protein level used designations for MEX3C

RNA-binding protein MEX3C , ring finger and KH domain containing 2 , mex-3 homolog C (C. elegans) , mex-3 homolog C , RING finger and KH domain-containing protein 2 , RING finger protein 194 , RNA-binding E3 ubiquitin-protein ligase MEX3C

GENE ID SPECIES
307271 Rattus norvegicus
455423 Pan troglodytes
549821 Xenopus (Silurana) tropicalis
476195 Canis lupus familiaris
100069803 Equus caballus
529318 Bos taurus
100713484 Cavia porcellus
51320 Homo sapiens
240396 Mus musculus
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