Mitochondrial Carrier 2 Protéines (MTCH2)

The substrate transported is not yet known. De plus, nous expédions MTCH2 Anticorps (64) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
MTCH2 23788 Q9Y6C9
Rat MTCH2 MTCH2 295922  
MTCH2 56428 Q791V5
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Showing 4 out of 4 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg 50 to 55 Days
$5,262.31
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg 50 to 55 Days
$7,493.38
Détails
Escherichia coli (E. coli) Souris His tag 0.05 mg 2 to 3 Days
$309.38
Détails
Wheat germ Humain GST tag 10 μg 11 to 12 Days
$414.29
Détails

MTCH2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine) ,
,

Plus protéines pour Mitochondrial Carrier 2 (MTCH2) partenaires d'interaction

Human Mitochondrial Carrier 2 (MTCH2) interaction partners

  1. study identified Cav1 and MTCH2 as the molecular targets of DHA and revealed a new link between the upstream Cav1/MTCH2 upregulation and the downstream activation of the cell death pathway involved in the DHA-mediated inhibition of cell viability.

  2. MTCH2 and cardiolipin participate in the recruitment and integration of tBID into the mitochondrial outer membrane.

  3. The BID-MTCH2 axis regulates the differentiation/apoptosis of stem cells and mitochondrial metabolism. (Review)

  4. Data indicate that Mtch2 accelerated conformational change in membrane-bound tBid (Bid) enables it to activate Bax.

  5. Compares and contrasts all the known human SLC25A* genes and includes functional information.

  6. Results imply a regulatory role for TMEM18, BDNF, MTCH2 and NEGR1 in adipocyte differentiation and biology. In addition, we show a variation of MAF expression during adipogenesis, while NPC1, PTER and SH2B1 were not regulated.

  7. Our study supports earlier reports of SH2B1 to be of importance in insulin sensitivity and, in addition, suggests potential roles of NEGR1 and MTCH2.

  8. Molecular basis of the interaction between proapoptotic truncated BID (tBID) protein and mitochondrial carrier homologue 2 (MTCH2) protein

  9. Gene-treatment interactions were observed for short-term weight loss. (MTCH2 rs10838738, Plifestyle*SNP = 0.022)

  10. MTCH2 may play a role in cellular processes underlying obesity

  11. MTCH2 rs 10838738 is associated with higher body mass index.

  12. Mtch2 is a mitochondrial target of tBID and possibly participates in the mitochondrial apoptotic program.

Zebrafish Mitochondrial Carrier 2 (MTCH2) interaction partners

  1. The findings indicate an essential role for mtch2 during organ development and adipogenesis in vivo.

Mouse (Murine) Mitochondrial Carrier 2 (MTCH2) interaction partners

  1. Mitochondrial Carrier Homolog 2 forebrain conditional knockout mice exhibit impaired spatial but not motor learning and an impairment in long-term potentiation in hippocampal slices.

  2. Mitochondrial carrier homolog 2 protein (MTCH2) knockout (-/-) embryonic stem cells (ESCs) fail to elongate their mitochondria and to alter their metabolism.

  3. MTCH2 is a critical player in neuronal cell biology, controlling mitochondria metabolism, motility and calcium buffering to regulate hippocampal-dependent cognitive functions.

  4. Results show that Mimp/Mtch2 overexpression alters lipid metabolism and may play a role in the onset of obesity and development of insulin resistance.

  5. MTCH2 is a conserved regulator of lipid homeostasis. MTCH2 was found to be both required and sufficient for lipid homeostasis shifts, suggesting that pharmacological inhibition of MTCH2 could be therapeutic for treatment of obesity and related disorders. MTCH2 could influence lipid homeostasis through inhibition of ESR1 activity.

  6. Loss of MTCH2 increases muscle metabolism, energy expenditure, heart function, and protects from diet-induced obesity.

  7. Loss of Mtch2 increases mitochondrial OXPHOS, triggering HSC entry into cycle. Elevated OXPHOS is accompanied by an increase in mitochondrial size, increase in ATP and ROS levels, and protection from irradiation-induced apoptosis.

  8. Data indicate that Mtch2 accelerated conformational change in membrane-bound tBid (Bid) enables it to activate Bax.

Profil protéine MTCH2

Profil protéine

The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity).

Gene names and symbols associated with MTCH2

  • mitochondrial carrier 2 (MTCH2)
  • mitochondrial carrier 2 L homeolog (mtch2.L)
  • mitochondrial carrier 2 (Mtch2)
  • mitochondrial carrier homolog 2 (mtch2)
  • 2310034D24Rik Protéine
  • 4930539J07Rik Protéine
  • fi20c06 Protéine
  • fj35g12 Protéine
  • HSPC032 Protéine
  • MIMP Protéine
  • SLC25A50 Protéine
  • wu:fi20c06 Protéine
  • wu:fj35g12 Protéine

Protein level used designations for MTCH2

2310034D24Rik , met-induced mitochondrial protein , mitochondrial carrier homolog 2 , solute carrier family 25, member 50 , etID15240.7

GENE ID SPECIES
23788 Homo sapiens
379498 Xenopus laevis
395597 Gallus gallus
337927 Bos taurus
295922 Rattus norvegicus
100174454 Pongo abelii
30655 Danio rerio
56428 Mus musculus
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