anti-Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) Anticorps

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. De plus, nous expédions Mitochondrially Encoded NADH Dehydrogenase 4 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MT-ND4 4538 P03905
MT-ND4 17719 P03911
MT-ND4    
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Top anti-Mitochondrially Encoded NADH Dehydrogenase 4 Anticorps sur anticorps-enligne.fr

Showing 5 out of 9 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Souris Lapin Inconjugué WB Western blot analysis of extracts of various cells, using MT-ND4 antibody. 100 μL Connectez-vous pour afficher 11 to 13 Days
$366.77
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cell lines, using MT-ND4 antibody. 200 μL Connectez-vous pour afficher 12 to 14 Days
$438.90
Détails
Humain Souris Inconjugué ELISA, WB Western Blot detection against Immunogen (32.05 KDa) . 50 μL Connectez-vous pour afficher 11 to 12 Days
$238.67
Détails
Souris Lapin Inconjugué WB Western blot analysis of extracts of various cell lines, using MT-ND4 antibody. 100 μL Connectez-vous pour afficher 13 to 14 Days
$393.25
Détails

Plus d’anticorps contre Mitochondrially Encoded NADH Dehydrogenase 4 partenaires d’interaction

Human Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) interaction partners

  1. This case series describes three patients with an ND4 m11778G > A mitochondrial DNA mutation who had the concomitant occurrence of Juvemile open-angle glaucoma and Lebers hereditary optic neuropathy.

  2. Our study suggests to include haplogroup T as a possible genetic background influencing LHON penetrance and to consider the increase of mtDNA copy number as a protective factor from vision loss regardless the hetero/homoplasmic status of LHON primary mutations.

  3. The mitochondrial haplogroup D4j specific m.11696G > A mutation may act in synergy with the primary Leber's hereditary optic neuropathy-associated m.11778G > A mutation, thereby increasing the penetrance and expressivity of visual loss in these Chinese families.

  4. This review focuses on the role of mitochondrial genes in causing LHON and therapeutics available for treating the disease. A systematic search has been adopted in various databases using the keywords "LHON," "mitochondria," "ND1," "ND4," "ND6," and "therapy" and the following review on mitochondrial genetics.

  5. In this study, 27.5% mutation was detected in North Indian LHON families. These results suggest that m.G11778A mutation is more frequent in this population. The results of the present study are compatible with studies of an Asian population and Northern European population.

  6. A missense mutation, m.11778G>A (p.R340H), in the ND4 gene was identified in eight patients and three asymptomatic carriers, even though the incidence of this has been considered low in Chinese population.

  7. The first detailed study of Indian LHON patients confirm that the m.11778G>A-related LHON in India coexists with multiple different mtDNA haplogroups, unlike the preferential association of west Eurasian haplogroup J and the reported increased clinical penetrance with the J2 subhaplogroup.

  8. MT-ND4 and MT-TL1 genetic variation might be associated with male infertility in Chinese patients.

  9. this paper identified m.11240C4T in ND4 as a novel mitochondrial disease-related mtDNA mutation in Leigh syndrome.

  10. We identified a genetic association between the MT-ND4 11719 A/G polymorphism and Ulcerative Colitis in the subgroup of males. The male-specific association indicates differences between males and females concerning the impact of mitochondrial gene polymorphisms on the development of Ulcerative Colitis.

  11. The molecular study of a family with one member with Leber hereditary optic neuropathy found the mitochondrial mutation m.11778G>A in MT-ND4.

  12. the ND4 gene is the hot spot for mutations associated with Leber's hereditary optic neuropathy

  13. Three mutations were significantly related to the presence of epilepsy. These mutations were found at the 8502, 11994, and 13,231 bp of mtDNA, which resulted in amino acid changes at the MT-ATP-8, MT-ND4 and MT-ND5 genes.

  14. Expression of WT human ND4 in cells with the G11778A mutation in ND4 led to restoration of defective ATP synthesis.

  15. altered activity of complex III modulates the phenotypic manifestation of Leber's hereditary optic neuropathy-associated ND4 G11778A mutation

  16. Patients with somatically acquired ND4 mutations had significantly longer relapse-free survival (P=0.017) and overall survival (OS) (P=0.021) than ND4(wildtype) patients

  17. Our data emphasize the important role of MTND mutations in the pathogenicity of MELAS, especially MELAS/LS overlap syndrome.

  18. The specific mtDNA background B5a1 was significantly associated with Southeast Asian G11778A LHON and appeared to modify the risk of visual loss.

  19. mitochondrial haplogroup M9a specific variant T3394C may modulate the phenotypic manifestation of LHON-associated G11778A mutation in Chinese pedigrees.

  20. These results suggest that a different set of LHON-causing mutations is present in the South Indian population than in the European population

Mouse (Murine) Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) interaction partners

  1. Cybrid mice showed normal respiratory function whether or not their mtDNA possessed the A11181G mutation of the mt-Nd4 gene, suggesting that the this mutation is not responsible for respiration defects found in SAMP8 mice.

Arabidopsis thaliana Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) interaction partners

  1. Data indicate that SLOW GROWTH 4 (SLO4) is a mitochondrial pentatricopeptide repeat (PPR) protein that is involved in editing NADH dehydrogenase subunit 4 (nad4), possibly required for the efficient splicing of NADH dehydrogenase subunit 2 (nad2) intron1.

  2. The data supports a model for MTSF1 functioning in which its association with the last nucleotides of the nad4 3' untranslated region stabilizes nad4 mRNA.

Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) profil antigène

Profil protéine

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Gene names and symbols associated with MT-ND4

  • NADH dehydrogenase, subunit 4 (complex I) (ND4) anticorps
  • NADH dehydrogenase subunit 4 (ND4) anticorps
  • NADH dehydrogenase subunit 4 (nad4) anticorps
  • NADH dehydrogenase subunit 4 (NAD4) anticorps
  • NADH dehydrogenasesubunit 4 (nad4) anticorps
  • MTND4 anticorps
  • NADH4 anticorps

Protein level used designations for MT-ND4

NADH dehydrogenase subunit 4

GENE ID SPECIES
4538 Homo sapiens
17719 Mus musculus
3283886 Bos taurus
804483 Canis lupus familiaris
807643 Gallus gallus
808510 Sus scrofa
808225 Oryctolagus cuniculus
2565705 Caenorhabditis elegans
814596 Arabidopsis thaliana
807666 Ascaris suum
807960 Locusta migratoria
802562 Candida albicans SC5314
808213 Branchiostoma lanceolatum
1734028 Acanthamoeba castellanii
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