anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3) Anticorps

The protein encoded by MAPK8IP3 shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. De plus, nous expédions et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MAPK8IP3 23162 Q9UPT6
MAPK8IP3 30957 Q9ESN9
MAPK8IP3 302983  
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Top anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 58 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Souris Chèvre Inconjugué IHC, ELISA   100 μg Connectez-vous pour afficher 6 to 7 Days
$429.84
Détails
Boeuf (Vache) Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of JIP3 staining in PC12 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of JIP3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IF, ELISA, WB Western blot analysis of extracts from HeLa cells, using JIP3 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using JIP3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using JIP-3 Polyclonal Antibody. 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Souris Chèvre Inconjugué IHC (p), IHC, ELISA Immunohistochemistry-Paraffin: JNK/JIP3 Antibody [ABIN249901] - (4ug/ml) staining of paraffin embedded Mouse Brain. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$488.73
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, WB Western blot analysis of extracts from HeLa cells, using JIP3 antibody. ABIN6274547 staining HeLa by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Souris Chèvre Inconjugué ELISA 0.1 mg Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Boeuf (Vache) Chèvre Inconjugué ELISA   100 μg Connectez-vous pour afficher 11 to 14 Days
$610.50
Détails
Humain Lapin Inconjugué ELISA, IF, IHC (p), WB 200 μL Connectez-vous pour afficher 12 to 14 Days
$438.90
Détails

anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 3 Anticorps mieux référencés

  1. Mouse (Murine) Polyclonal MAPK8IP3 Primary Antibody pour IHC (p), IHC - ABIN249901 : Kelkar, Gupta, Dickens, Davis: Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3. dans Molecular and cellular biology 2000 (PubMed)

Plus d’anticorps contre Mitogen-Activated Protein Kinase 8 Interacting Protein 3 partenaires d’interaction

Zebrafish Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3) interaction partners

  1. our data provide strong evidence that Jip3 in fact serves as an adapter protein linking these cargos to dynein

Human Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3) interaction partners

  1. JIP3 was highly expressed in hearts with hypertrophic cardiomyopathy. The findings indicated that blockage of JIP3 could alleviate cardiac hypertrophy via inactivating JNK pathway, and thus might be a promising strategy to prevent pathological cardiac hypertrophy.

  2. The crystal structure of an N-terminally truncated form of LZII of JIP3 alone shows an unexpected antiparallel arrangement.

  3. Results demonstrated the increased expression of JIP3 in the temporal neocortex of TLE patients and in the experimental model of epileptic seizures

  4. JSAP1 and JLP play critical roles in kinesin-1-dependent axonal transport

  5. The results of this study finding suggested that a model by which the self-assembly of SYD-2/Liprin-alpha proteins mediated by the coiled-coil LH1 domain is one of the key steps to the accumulation of presynaptic components at nascent synaptic junctions

  6. This study demonistrated that JIP3 mediates TrkB axonal anterograde transport and enhances BDNF signaling by directly bridging TrkB with kinesin-1.

  7. Expression of constitutively active PI3K stimulated translocation of Tiam1 to the membrane, increased Rac1 activity, and increased wound healing of airway epithelial cells. Increased Rac1 activity resulted in increased phosphorylation of JNK1.

  8. demonstration that JSAP1 bound ASK1 and enhanced ASK1- and H2O2-induced JNK activity

  9. Pressure application of 160 mmHg for 3 h produced cell proliferation and activated ERK and c-JUN N-terminal kinase

  10. JIP1 and JIP3, have a cross-talk that leads to the regulation of the ASK1-SEK1-JNK signal during glucose deprivation; cross-talk between JIP3 and JIP1 is mediated through SEK1-JNK2 and Akt1.

  11. JSAP1.FAK complex functions cooperatively as a scaffold for the JNK signaling pathway and regulator of cell migration on FN

  12. Upon UVB-induced stress in keratinocytes, ROCK1 was activated, bound to JIP-3, and activated the JNK pathway

  13. Cyclic mechanical strain impairs signaling of cell migration after injury via a pathway that involves FAK-JIP3-JNK.

Mouse (Murine) Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3) interaction partners

  1. JIP3-KO mice after aortic banding exhibited attenuated cardiac function, reduced fibrosis levels and decreased hypertrophic marker proteins. Loss of JIP3 also ameliorated oxidative stress, inflammatory response, apoptosis and endoplasmic reticulum (ER) stress in hearts.

  2. JIP3 absence is associated with decreased lipogenesis, oxidative stress and inflammation, supplying a new target for nonalcoholic fatty liver disease treatment.

  3. These results establish the critical role of JIP3-dependent axonal lysosome transport in regulating amyloidogenic amyloid precursor protein processing and support a model wherein Abeta production is amplified by plaque-induced axonal lysosome transport defects.

  4. Data show that c-Jun NH2-terminal kinase (JNK)-interacting protein-3 (JIP3) participates in the migration of cortical neurons during cortical development by mediating TrkB receptor axonal anterograde transport.

  5. JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degeneration

  6. Results demonstrated the increased expression of JIP3 in the temporal neocortex of TLE patients and in the experimental model of epileptic seizures

  7. These findings reveal that JIP3 regulation of kinesin-1 motility is critical for axon elongation and regeneration.

  8. JSAP1 and JLP, which might be paralogous to each other, are critical and functionally redundant in cytokinesis and control ARF6 localization to the midbody by forming a tripartite complex of JSAP1/JLP, active ARF6, and kinesin-1.

  9. JIP3 regulates neuronal axon elongation in a kinesin- and JNK-dependent manner

  10. Results suggest that JSAP1 is required for the pathfinding of the developing telencephalic commissures in the early brains.

  11. syd activates kinesin heavy chain for transport & enhances its motility, increasing its velocity & run length. syd mutants binding KHC but not kinesin light chain are transported to axons & dendrites normally.

  12. The results provide evidence that ARF6/JIP3 signaling regulates neurite morphogenesis.

  13. Results suggest that endocytic sunday driver (syd) vesicles function in part to carry injury signals back to the cell body, whereas anterograde syd vesicles may play a role in axonal outgrowth and guidance.

  14. Jip3 gene disruption causes severe defects in the morphogenesis of the telencephalon.

  15. identified JNK-interacting protein 3 (JIP3), a scaffold protein for JNK, as a TLR4-associated protein

  16. JSAP1 is required for early embryonic neurogenesis

  17. form activated by platelet-derived growth factor receptor-alpha is needed for platelet-derived growth factor induced p21WAF1/CIP1 promoter activity independent of p53

  18. RelA antagonizes TNFR1-JNK proliferative signals in epidermis and plays a nonredundant role in restraining epidermal growth.

  19. c-jun amino-terminal kinase has a role in regulation of the neural differentiation of P19 cells

  20. L5 spinal nerve ligation induces differential activation of MAPK in injured and uninjured DRG neurons. MAPK activation in the primary afferents may participate in generating pain hypersensitivity after partial nerve injury.

Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3) profil antigène

Profil protéine

The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with MAPK8IP3

  • mitogen-activated protein kinase 8 interacting protein 3 (MAPK8IP3) anticorps
  • mitogen-activated protein kinase 8 interacting protein 3 (mapk8ip3) anticorps
  • mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3) anticorps
  • BB120594 anticorps
  • D17Wsu15e anticorps
  • JIP-3 anticorps
  • Jip3 anticorps
  • JSAP1 anticorps
  • JSAP1a anticorps
  • JSAP1b anticorps
  • JSAP1c anticorps
  • JSAP1d anticorps
  • mKIAA1066 anticorps
  • syd anticorps
  • Syd2 anticorps

Protein level used designations for MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3 , C-Jun-amino-terminal kinase-interacting protein 3 , JNK-interacting protein 3 , jip3 , c-Jun-amino-terminal kinase-interacting protein 3-like , C-jun-amino-terminal kinase interacting protein 3 , JIP-3 , JNK MAP kinase scaffold protein 3 , JNK/SAPK-associated protein-1 , JNK/stress-activated protein kinase-associated protein 1 , homolog of Drosophila Sunday driver 2 , mitogen-activated protein kinase 8-interacting protein 3 , JNK/SAPK-associated protein 1 , JNK/SAPK-associated protein 1c , JUN/SAPK-associated protein 1 , c-Jun NH2-terminal kinase (JNK)/stress-activated protein kinase-associated protein 1 , mitogen activated protein kinase 8 interacting protein 3 , sunday driver 2

GENE ID SPECIES
426986 Gallus gallus
537598 Bos taurus
702388 Macaca mulatta
100067809 Equus caballus
100227405 Taeniopygia guttata
100318355 Danio rerio
100521718 Sus scrofa
23162 Homo sapiens
30957 Mus musculus
302983 Rattus norvegicus
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