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MST interaction with MOB1 is not essential for development and tissue growth control.
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We identified a direct target of miR-155 as MAP3K10 in osteosarcoma
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MAP3K4 is sufficiently mediate the TGFbeta-induced phosphorylation of p38 MAPK in MEFs and HaCaT cells.
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A novel and important role for MAP3K10 in the proliferation and chemoresistance of pancreatic ductal adenocarcinoma.
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This study showed that show that RUNX3 is a principal and evolutionarily conserved component of the MST pathway.
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Mechanism of MAP kinase activation by TNF requires Src-dependent activation of Vav, activation of Rac/Cdc42, and the engagement of the Rac/Cdc42 interaction site on MLK2 and 3.
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Data show that miR-181b contributed to proliferation of AML cells by targeting MLK2.
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MLK2 has a role in vesicle formation and endosome recycling by binding to clathrin
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demonstrate Alien-MLK2 interaction and also show that MLK2 is able to phosphorylate Alien; Alien, DAX-1 and thyroid hormone receptor mediated transcriptional silencing is strongly enhanced in the presence of active MLK2
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MLK2 and -3 are required for activation of JNK and p38 by ectopically expressed GCK
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Hippocalcin and MLK2 were colocalized in the halo of Lewy bodies in Parkinson disease patients, and neither protein was detected in normal pigmented neurons.
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Mixed lineage kinase phosphorylates transcription factor E47 and inhibits TrkB expression to link neuronal death and survival pathways