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The protein encoded by MAP3K10 is a member of the serine/threonine kinase family. De plus, nous expédions MAP3K10 Protéines (7) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal MAP3K10 Primary Antibody pour IHC (p), WB - ABIN392424
Humphrey, Newcomb, Yu, Hao, Yu, Krajewski, Du, Jhala: Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells. dans The Journal of biological chemistry 2010
Show all 5 Pubmed References
MST interaction with MOB1 (Montrer MOBKL3 Anticorps) is not essential for development and tissue growth control.
We identified a direct target of miR (Montrer MLXIP Anticorps)-155 as MAP3K10 in osteosarcoma
MAP3K4 (Montrer MAP3K4 Anticorps) is sufficiently mediate the TGFbeta (Montrer TGFB1 Anticorps)-induced phosphorylation of p38 MAPK (Montrer MAPK14 Anticorps) in MEFs and HaCaT cells.
A novel and important role for MAP3K10 in the proliferation and chemoresistance of pancreatic ductal adenocarcinoma.
This study showed that show that RUNX3 (Montrer RUNX3 Anticorps) is a principal and evolutionarily conserved component of the MST pathway.
Mechanism of MAP kinase (Montrer MAPK1 Anticorps) activation by TNF (Montrer TNF Anticorps) requires Src (Montrer SRC Anticorps)-dependent activation of Vav (Montrer VAV1 Anticorps), activation of Rac (Montrer AKT1 Anticorps)/Cdc42 (Montrer CDC42 Anticorps), and the engagement of the Rac (Montrer AKT1 Anticorps)/Cdc42 (Montrer CDC42 Anticorps) interaction site on MLK2 and 3.
Data show that miR (Montrer MLXIP Anticorps)-181b contributed to proliferation of AML (Montrer RUNX1 Anticorps) cells by targeting MLK2.
MLK2 has a role in vesicle formation and endosome recycling by binding to clathrin
demonstrate Alien-MLK2 interaction and also show that MLK2 is able to phosphorylate Alien; Alien, DAX-1 (Montrer NR0B1 Anticorps) and thyroid hormone receptor (Montrer THRA Anticorps) mediated transcriptional silencing is strongly enhanced in the presence of active MLK2
MLK2 and -3 are required for activation of JNK (Montrer MAPK8 Anticorps) and p38 (Montrer CRK Anticorps) by ectopically expressed GCK (Montrer GCK Anticorps)
There is extensive functional redundancy between MLK1 (Montrer MAP3K9 Anticorps) and MLK2, and the other member of the family, MLK3 (Montrer KCNK7 Anticorps), none of which are required for survival in mouse.
Mixed lineage kinase (Montrer MAP3K12 Anticorps) phosphorylates transcription factor E47 (Montrer TCF3 Anticorps) and inhibits TrkB (Montrer NTRK2 Anticorps) expression to link neuronal death and survival pathways
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
mitogen-activated protein kinase kinase kinase 10
, mixed-lineage kinase 2
, MKN28 derived nonreceptor_type serine/threonine kinase
, MKN28 kinase
, mixed lineage kinase 2
, protein kinase MST
, MKN28 derived nonreceptor_type
, serine/threonine kinase