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The protein encoded by MAP4K2 is a member of the serine/threonine protein kinase family. De plus, nous expédions MAP4K2 Protéines (6) et beaucoup plus de produits pour cette protéine.
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These studies demonstrate, for the first time, that GCK (Montrer GCK Anticorps) is a molecular therapeutic target in DLBCL tumors and that inhibiting GCK (Montrer GCK Anticorps) may significantly extend DLBCL patient survival.
Data indicate 4-substituted 1H-pyrrolo[2,3-b]pyridines as potent inhibitors against TGFbeta (Montrer TGFB1 Anticorps)-activated kinase 1 (TAK1 (Montrer MAP3K7 Anticorps)) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2).
Intermediates in the guanine nucleotide exchange reaction of Rab8 (Montrer RAB8A Anticorps) protein catalyzed by guanine nucleotide exchange factors Rabin8 (Montrer RAB3IP Anticorps) and GRAB.
Data suggest that the Rabin8 (Montrer RAB3IP Anticorps)-Rab8 (Montrer RAB8A Anticorps)-Sec15 (Montrer EXOC6 Anticorps) interaction may couple the activation of Rab8 (Montrer RAB8A Anticorps) to the recruitment of the Rab8 (Montrer RAB8A Anticorps) effector and is involved in the regulation of vesicular trafficking for primary cilium formation.
CCM3 (Montrer PDCD10 Anticorps) is located on the Golgi apparatus, forming a complex with proteins of the germinal center kinase III (GCKIII) family and GM130 (Montrer GOLGA2 Anticorps), a Golgi-resident protein.
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
B lymphocyte serine/threonine protein kinase
, MAPK/ERK kinase kinase kinase 2
, MEK kinase kinase 2
, MEKKK 2
, Rab8 interacting protein
, germinal centre kinase (GC kinase)
, RAB8 interacting protein
, germinal center kinase
, mitogen activated protein kinase kinase kinase kinase 2
, rab8-interacting protein
, mitogen-activated protein kinase kinase kinase kinase 2
, mitogen-activated protein kinase kinase kinase kinase 2-like
, mitogen-activated protein kinase kinase kinase kinase 3-like