Mucin 13, Cell Surface Associated (MUC13) Kits ELISA

Human Mucin 13, Cell Surface Associated (MUC13) interaction partners

1. The results suggest that MUC13 overexpression and loss of expression of AGR2 may predict the progression of Intraductal papillary mucinous neoplasm and an unfavorable prognosis in patients with Intraductal papillary mucinous neoplasm

2. our study first demonstrated that USF1 could activate the transcription of MUC13, thereby enhancing the proliferation and self-renewal of glioblastoma stem cells

3. MUC13 high expression is a novel independent adverse prognostic factor of clinical outcome in non-metastatic clear cell renal cell carcinoma patients after surgery.

4. Luciferase assays and western blot confirmed MUC13 as a target gene of miR1323p.

5. Results from this study demonstrate that MUC13 Functionally interacts and activates HER2 at p1248 in PDAC cells, leading to stimulation of HER2 signaling cascade, including ERK1/2, FAK, AKT and PAK1 as well as regulation of the growth, cytoskeleton remodeling and motility, invasion of PDAC cells-all collectively contributing to PDAC progression.

6. High MUC13 expression is associated with renal cell carcinoma and drug resistance.

7. A combination of MUC13/MUC20 expression was a potential prognostic marker for patients with ESCC, who received neoadjuvant chemotherapy followed by surgery.

8. Results show that pancreatic ductal adenocarcinoma cells express higher levels of MUC13 and is associated with poor outcome when expressed at low level.

9. Based on nasopharyngeal MUC13 gene expression in readily available Nasopharyngeal aspirate samples , we can discriminate between severity of disease in Respiratory syncytial virus infected infants.

10. These results suggest miR-145 as a novel regulator of MUC13 in pancreatic cancer.

11. Overexpression of MUC13 increased cell growth, colony formation, cell migration, and invasion in colon cancer cells.

12. MUC13 is epigenetically regulated in ovarian cancer.

13. Overexpression of MUC13 is associated with pancreatic neuroendocrine tumors.

14. GALNT14 may contribute to ovarian carcinogenesis through aberrant glycosylation of MUC13.

15. Metastatic colon cancer and liver metastasis tissue samples demonstrated significantly (p<0.05) higher cytoplasmic and nuclear MUC13 expression compared with non-metastatic colon cancer and adjacent normal colon samples.

16. MUC13 overexpression caused a significant increase in cell motility, invasion, proliferation, and anchorage-dependent or -independent clonogenicity while decreasing cell-cell and cell-substratum adhesion in pancreatic cancer.

17. The various functional domains of MUC13 may confer oncogenic potential to MUC13

18. MUC13 is a good differentiation marker for gastrointestinal mucosa

19. Aberrant intestinal expression and allelic variant MUC13 is associated with inflammatory bowel disease.

20. Reflux laryngitis is associated with down-regulation of mucin gene expression.

Pig (Porcine) Mucin 13, Cell Surface Associated (MUC13) interaction partners

1. An orphan gene or trans-acting element present in the MUC13 gene region has an effect on the glycosylation of F4 binding proteins in E coli.

2. Susceptibility towards enterotoxigenic Escherichia coli F4ac diarrhea is governed by the MUC13 gene in pigs

3. This study suggests that expression of MUC13 and MUC20 is not related to the susceptibility of piglets to enterotoxigenic E. coli-F4ac.

4. MUC13 is in strong linkage disequilibrium with the ETEC F4ab/ac receptor locus

Mouse (Murine) Mucin 13, Cell Surface Associated (MUC13) interaction partners

1. these data indicate that combining chemotherapy and MUC13 antagonism could improve the treatment of metastatic cancers

2. Muc13 was upregulated in the fundus of the stomach already 1 day after infection with Helicobacter heilmannii.

3. these studies demonstrate that MUC1 and MUC13 are important components of gastrointestinal homeostasis and that disruption or inappropriate expression of these mucins could predispose to infectious and inflammatory disease and inflammation-induced cancer.

4. protective role in the colonic epithelium by inhibiting toxin-induced apoptosis

5. hypothesize that NJ-1(+)megakaryocytes (MKs) are immature MKs and the NJ-1 molecule is involved in MK adhesion to endothelial cells [NJ-1]