Murine Retrovirus Integration Site 1 Homolog Protéines (MRVI1)

MRVI1 is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). De plus, nous expédions Murine Retrovirus Integration Site 1 Homolog Anticorps (6) et Murine Retrovirus Integration Site 1 Homolog Kits (5) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
MRVI1 17540 Q9WUX5
MRVI1 10335 Q9Y6F6
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top Murine Retrovirus Integration Site 1 Homolog Protéines sur anticorps-enligne.fr

Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 60 to 65 Days
$7,639.51
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 60 to 65 Days
$10,888.92
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails

MRVI1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)

Human ,
,

Plus protéines pour Murine Retrovirus Integration Site 1 Homolog (MRVI1) partenaires d'interaction

Mouse (Murine) Murine Retrovirus Integration Site 1 Homolog (MRVI1) interaction partners

  1. cGKIbeta signaling via IRAG is essential for regulation of smooth muscle tone and of intracellular calcium by NO and by atrial natriuretic peptide (Montrer NPPA Protéines).

  2. conclude that cGMP-dependent relaxation of hormone receptor (Montrer NR4A1 Protéines)-triggered smooth muscle contraction essentially depends on the interaction of cGKI (Montrer PRKG1 Protéines)-IRAG with IP(3)RI

  3. Reports use of non-AUG (CUG) translation initiation codon in one of the transcript variants of MRVI1 gene in mouse and human.

Human Murine Retrovirus Integration Site 1 Homolog (MRVI1) interaction partners

  1. In the present study we analyzed the structure and function of the human IRAG/MRVI1 gene

  2. IRAG is required for PKG1beta-regulated cyclic calcium release during motility of osteoclasts

  3. IRAG appears to be essentially involved in the NO/cGK (Montrer PRKG1 Protéines)-dependent inhibition of InsP(3)-dependent Ca(2 (Montrer CA2 Protéines)+)-signaling in colonic smooth muscle

  4. cGMP-dependent protein kinase (Montrer CDK7 Protéines) Ibeta binds to TFII-I (Montrer GTF2I Protéines) and IRAG through a common interaction motif

  5. These findings reveal that interaction between IRAG and InsP3RI has a central role in NO/cGMP-dependent inhibition of platelet aggregation and in vivo thrombosis.

  6. Reports use of non-AUG (CUG) translation initiation codon in one of the transcript variants of MRVI1 gene in mouse and human.

Cow (Bovine) Murine Retrovirus Integration Site 1 Homolog (MRVI1) interaction partners

  1. cGKIbeta signaling via IRAG is essential for regulation of smooth muscle tone and of intracellular calcium by NO and by atrial natriuretic peptide (Montrer NPPA Protéines).

  2. cGMP-dependent protein kinase (Montrer CDK7 Protéines) Ibeta binds to TFII-I (Montrer GTF2I Protéines) and IRAG through a common interaction motif

Profil protéine Murine Retrovirus Integration Site 1 Homolog (MRVI1)

Profil protéine

This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used.

Gene names and symbols associated with MRVI1

  • MRV integration site 1 (Mrvi1)
  • murine retrovirus integration site 1 homolog (MRVI1)
  • BB115629 Protéine
  • IRAG Protéine
  • JAW1L Protéine
  • Ris1 Protéine

Protein level used designations for MRVI1

JAW1-related protein MRVI1 , inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate , inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate , murine retrovirus integration site 1 protein , protein MRVI1 , retroviral integration site 1 , IP3R-associated cGMP kinase substrate , IP3 receptor associated cGMP kinase substrate

GENE ID SPECIES
17540 Mus musculus
10335 Homo sapiens
281918 Bos taurus
Fournisseurs de qualité sélectionnés pour Murine Retrovirus Integration Site 1 Homolog Protéines (MRVI1)
Avez-vous cherché autre chose?