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Involved in meiotic recombination. De plus, nous expédions MSH4 Anticorps (45) et beaucoup plus de produits pour cette protéine.
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Study describes the first MSH4 mutation associated with POI and increases the number of meiotic/DNA repair genes formally implicated as being responsible for this condition.
inactivation of MSH4 in germ cells may have played a role in the acquisition of additional TP53 and LATS1 germline mutations in a Li-Fraumeni family
hMSH4 interacts with HDAC3 (Montrer HDAC3 Protéines).
Our current study has revealed a role for hMSH4 in the maintenance of genomic stability by suppressing NHEJ-mediated DSB repair.
mutation analysis of SYCP3 (Montrer SYCP3 Protéines), DNMT3L (Montrer TRDMT1 Protéines) and MSH4 in patients with maturation arrest of spermatogenesis and couples with recurrent miscarriages
Mutations within the hMLH1 and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha
The different properties associated with these two hMSH5 (Montrer MSH5 Protéines) variants underscore the potential functional diversity of the human hMSH5 (Montrer MSH5 Protéines) gene.
the GPS2 (Montrer GPS2 Protéines) might function in concert with hMSH4-hMSH5 (Montrer MSH5 Protéines) during the process of homologous recombination.
A review of the properties and functional roles of MSH4.
Dimerization of MSH4 and MSH5 (Montrer MSH5 Protéines) facilitates their nuclear localization suggesting that dimerization may regulate the intracellular trafficking of these proteins.
Study suggests that the dynamic interchromosomal (intergenic) trans-splicing generates functional diversity of the mouse Msh4 gene.
Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis.
mutS protein homolog 4
, mutS homolog 4 (E. coli)
, mutS protein homolog 4-like
, mutS homolog 4
, MutS homolog 4 variant iota 1
, MutS homolog 4 variant theta 1