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May activate or repress transcription via interactions with sequence specific DNA-binding proteins. De plus, nous expédions MYBBP1A Kits (3) et MYBBP1A Protéines (3) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal MYBBP1A Primary Antibody pour WB - ABIN1881560
Perrera, Colombo, Valsasina, Carpinelli, Troiani, Modugno, Gianellini, Cappella, Isacchi, Moll, Rusconi: Identification of Myb-binding protein 1A (MYBBP1A) as a novel substrate for aurora B kinase. dans The Journal of biological chemistry 2010
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Human Polyclonal MYBBP1A Primary Antibody pour ICC, IF - ABIN253189
Nahálková, Tomkinson: TPPII, MYBBP1A and CDK2 form a protein-protein interaction network. dans Archives of biochemistry and biophysics 2014
Guinea Pig Polyclonal MYBBP1A Primary Antibody pour IHC, WB - ABIN2780004
Fan, Rhee, St-Pierre, Handschin, Puigserver, Lin, Jäeger, Erdjument-Bromage, Tempst, Spiegelman: Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. dans Genes & development 2004
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Mybbp1a is a novel negative regulator of Sirt7 (Montrer SIRT7 Anticorps).
Data show that down-regulation of MYBBP1A decreases the growth rate of wild type mouse embryonic stem cells, embryo fibroblasts (MEFs) and of human HeLa cells, where it also promotes apoptosis.
Mybbp1a may play a dual role in the rRNA metabolism, potentially linking and coordinating ribosomal DNA transcription and pre-rRNA processing to allow for the efficient synthesis of ribosomes.
Myb-binding protein 1a was identified as a novel negative regulator of muscle-specific (Montrer EIF3K Anticorps) gene expression and myoblast differentiation.
Myb (Montrer MYB Anticorps)-binding protein p160 (Montrer MSH6 Anticorps) is a novel target of the von Hippel-Lindau tumor suppressor.
Ipr1 (Montrer SP110 Anticorps) might be involved in apoptosis pathway via MYBBP1A.
Myb-binding protein 1a augments AhR (Montrer AHR Anticorps)-dependent gene expression
Mybbp1a is a nucleocytoplasmic shuttling protein involved in nuclear import and export via CRM1 (Montrer XPO1 Anticorps)-dependent and -independent pathways.
These data show that p160 (Montrer MSH6 Anticorps) is a novel regulator of Prep1-Pbx1 (Montrer PBX1 Anticorps) transcriptional activity.
SRC-3 (Montrer NCOA3 Anticorps) alone of the p160 (Montrer MSH6 Anticorps) coactivators enhanced CAR transactivation in hepatic cells without PB treatment.
The results indicated that both the heterozygous genotype GC and homozygous genotype CC in rs3809849 in MYBBP1A had significant effects on the risk of pulmonary tuberculosis, and heterozygous genotype CT in rs9061 in SP110 (Montrer SP110 Anticorps) also had similar effects.
We propose that the nucleolus functions as a stress sensor to modulate p53 (Montrer TP53 Anticorps) protein levels and its acetylation status, determining cell fate between cell cycle arrest and apoptosis by regulating MYBBP1A translocation.
MYBBP1A(low)AKT (Montrer AKT1 Anticorps)(Ser473)(high) staining pattern serves not only as a marker for the pre-senescent stage but also as an indicator of OPSCC patients at high risk for treatment failure.
TPPII (Montrer Tpp2 Anticorps), MYBBP1A and CDK2 (Montrer CDK2 Anticorps) form a protein-protein interaction network.
MYBBP1A functions to enhance p53 (Montrer TP53 Anticorps) tetramerization that is necessary for p53 (Montrer TP53 Anticorps) activation.
Regulators, including BCL11A (Montrer BCL11A Anticorps), MYB (Montrer MYB Anticorps), and KLF1 (Montrer KLF1 Anticorps), hold great promise to develop targeted and more effective approaches for HbF induction.
MYBBP1A-p53 (Montrer TP53 Anticorps) binding property can account for efficient p53 (Montrer TP53 Anticorps)-activation by MYBBP1A under nucleolar stress. Our results support the idea that MYBBP1A plays catalytic roles in p53 (Montrer TP53 Anticorps) acetylation and activation
Suggest that MYBBP1A is required for p53 (Montrer TP53 Anticorps) activation during anoikis; therefore, it is involved in suppressing colony formation and the tumorigenesis of breast cancer cells.
May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity).
MYB binding protein (P160) 1a
, MYB binding protein 1a
, myb-binding protein 1A-like
, myb-binding protein 1A
, myb-binding protein of 160 kDa
, nuclear protein P160
, MYB binding protein 1a
, PAR interacting protein
, PAR-interacting protein
, p53-activated protein-2
, myb-binding protein 1A-like protein