Myeloid Leukemia Factor 1 (MLF1) Kits ELISA

MLF1 encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. De plus, nous expédions MLF1 Anticorps (135) et MLF1 Protéines (8) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
MLF1 4291 P58340
MLF1 17349 Q9QWV4
Anti-Rat MLF1 MLF1 310483  
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Top MLF1 Kits ELISA sur anticorps-enligne.fr

Showing 3 out of 5 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$838.60
Détails
Souris < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests 11 to 18 Days
$838.60
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Boeuf (Vache)
  96 Tests 15 to 18 Days
$1,029.60
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Plus Kits ELISA pour MLF1 partenaires d'interaction

Human Myeloid Leukemia Factor 1 (MLF1) interaction partners

  1. Mutation in HTT causes Huntington's disease (HD); aggregates of mutated HTT cause apoptosis in neurons of HD patients. Data suggest that both MLF1 and MLF2 preferentially interact with mutated N-terminal HTT; MLF1/MLF2 reduce number of neurons (Neuro2A cell line) containing mutant HTT aggregates and subsequent apoptosis. (HTT = Huntingtin protein; MLF = myeloid leukemia factor)

  2. The data indicate that MLF1 serves as a proapoptotic antagonist that interacts with the HAX1/HtrA2-OMI/PARL (HOP) mitochondrial complex to modulate cell survival.

  3. These findings suggest that MLF and the associated co-chaperones play a direct role in modulating gene transcription.

  4. SNP associated with neuroblastoma resides upstream of the MLF1. Gene silencing of MLF1 in neuroblastoma cells results in significant growth inhibition.

  5. Data indicte that acute myeloid leukemia (AML) with NPM1-MLF1 and AML with NPM1 mutations showed similar immunophenotypical and molecular features, including gene mutation patterns and gene expression profiling (GEP).

  6. The subcellular localization of full-length human MLF1 is 14-3-3epsilon-independent.

  7. changes in the subcellular localization of NPM, due to alterations in the relative abundance of NPM and NPM-MLF1 proteins, may contribute to the enhanced myeloid progenitor activity of Npm +/- cells

  8. Data present the high-resolution crystal structure of this binding motif [MLF1(29-42)pSer34] in complex with 14-3-3epsilon and analyse the interaction with isothermal titration calorimetry.

  9. MLF1 gene rearrangement is associated with acute myeloid leukemia.

  10. phosphorylation of 14-3-3 binding site by MADM

  11. These findings suggest that an NPM/MLF1 fusion is the primary molecular abnormality in t(3;5) MDS and AML with multilineage dysplasia, and that cases with NPM/MLF1 may be clinically distinct from other MDS-associated disease

  12. Over-expression of MLF1 has little impact on skeletal muscle function in mice; progressive formation of protein aggregates in muscle are not necessarily pathogenic; MLF1 and MRJ may function together to ameliorate the toxic effects of mutant proteins.

  13. shuttling of MLF1 is critical for the regulation of cell proliferation and a disturbance in the shuttling balance increases the cell's susceptibility to oncogenic transformation

Mouse (Murine) Myeloid Leukemia Factor 1 (MLF1) interaction partners

  1. The data indicate that MLF1 serves as a proapoptotic antagonist that interacts with the HAX1/HtrA2-OMI/PARL (HOP) mitochondrial complex to modulate cell survival.

  2. Ectopically expressed MLF1 could be responsible for the pathological apoptosis in early myelodysplastic syndrome (MDS) patients.

  3. Mlf1 translocates between nucleus and cytoplasm, associates with a novel hnRNP, and influences gene expression

  4. shuttling of MLF1 is critical for the regulation of cell proliferation and a disturbance in the shuttling balance increases the cell's susceptibility to oncogenic transformation

MLF1 profil antigène

Antigen Summary

This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MLF1

  • myeloid leukemia factor 1 (MLF1) anticorps
  • myeloid leukemia factor 1 L homeolog (mlf1.L) anticorps
  • myeloid leukemia factor 1 (mlf1) anticorps
  • myeloid leukemia factor 1 (Mlf1) anticorps
  • HLS7 anticorps
  • MLF1 anticorps

Protein level used designations for MLF1

myeloid leukemia factor 1 , myelodysplasia-myeloid leukemia factor 1 , hematopoietic lineage switch 7

GENE ID SPECIES
425019 Gallus gallus
460811 Pan troglodytes
477127 Canis lupus familiaris
496153 Xenopus laevis
100135130 Xenopus (Silurana) tropicalis
4291 Homo sapiens
17349 Mus musculus
310483 Rattus norvegicus
533379 Bos taurus
100174592 Pongo abelii
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