Myocilin (MYOC) Kits ELISA

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function.

list all ELISA KIts Gène GeneID UniProt
Anti-Souris MYOC MYOC 17926 O70624
Anti-Humain MYOC MYOC 4653 Q99972
Anti-Rat MYOC MYOC 81523 Q9R1J4
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top Myocilin Kits ELISA sur anticorps-enligne.fr

Showing 2 out of 7 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.039 U/mL 0.156-10 U/mL Typical standard curve 96 Tests Connectez-vous pour afficher 15 to 18 Days
$910.56
Détails
Humain < 0.26 ng/mL 0.781 ng/mL - 50 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
Détails

Plus Kits ELISA pour Myocilin partenaires d'interaction

Mouse (Murine) Myocilin (MYOC) interaction partners

  1. mutant myocilin induces abnormal ECM (Montrer MMRN1 Kits ELISA) accumulation in the ER of TM cells, which may be responsible for reduced outflow facility and IOP elevation in myocilin-associated glaucoma.

  2. Mutated myocilin and heterozygous Sod2 (Montrer SOD2 Kits ELISA) deficiency act synergistically in a mouse model of open-angle glaucoma

  3. myocilin promotes cell proliferation and resistance to apoptosis via the ERK1/2 (Montrer MAPK1/3 Kits ELISA) MAPK (Montrer MAPK1 Kits ELISA) signaling pathway.

  4. Myocilin binds to ErbB2 (Montrer ERBB2 Kits ELISA)/ErbB3 (Montrer ERBB3 Kits ELISA), activates these receptors, and affects the downstream PI3K-AKT (Montrer AKT1 Kits ELISA) signaling pathway

  5. Myocilin also stimulated osteogenic differentiation of wild-type MSCs, which was associated with activation of the p38 (Montrer CRK Kits ELISA), Erk1/2 (Montrer MAPK1/3 Kits ELISA), and JNK (Montrer MAPK8 Kits ELISA) MAP kinase (Montrer MAPK1 Kits ELISA) signaling pathways

  6. We suggest that intracellular myocilin plays a role as a regulator of muscle hypertrophy pathways, acting through the components of dystrophin (Montrer DMD Kits ELISA) associated protein complex.

  7. The TIGR is implicated in resistance to oxidative stress. Despite the presence of a SOD motif, which is necessary for protection in mammalian cells, the protein is not a functional SOD, but might be involved in SOD activity.

  8. TIGR is a newly identified component of the CNS glial scar that is likely to contribute to neuronal regenerative failure characteristic of the mammalian CNS.

  9. Results do not support a causative role for increased MYOC levels or the MYOC gene in steroid-induced glaucoma.

  10. Results show that myocilin and gamma-synuclein interact and as a result, myocilin's properties are changed.

Human Myocilin (MYOC) interaction partners

  1. Juvenile onset open angle glaucoma and adult onset POAG form a spectrum of phenotypes. we analyzed the common variants in MYOC and CYP1B1 (Montrer CYP1B1 Kits ELISA) that were shared among all the three phenotypes .An interesting finding was that, while, many CYP1B1 (Montrer CYP1B1 Kits ELISA) variants were found in all three types of glaucoma, there was no reported MYOC variant, that was common to all the three primary glaucomas.

  2. present work reveals that FOXC1 (Montrer FOXC1 Kits ELISA) is an important regulator of exocytosis and establishes a new link between FOXC1 (Montrer FOXC1 Kits ELISA) and MYOC-associated glaucoma

  3. The four detected MYOC mutations appeared to be associated with morphologic changes in the trabecular meshwork and the underlying pathogenesis of a subtype of familial primary open angle glaucoma.

  4. The mutations c.1456C < T (p.L486F) in MYOC and c.322G < A (p.V108I) in B4GALT3 (Montrer B4GALT3 Kits ELISA) are likely responsible for the pathogenesis of Primary Open-angle Glaucoma in this family.

  5. Our findings demonstrated that MYOC cascade genetic testing for POAG allows identification of at-risk individuals at an early stage or even before signs of glaucoma are present. To our knowledge, this is the first study to demonstrate the clinical utility of predictive genetic testing for MYOC glaucoma.

  6. regulation by retinoic acid acts through the MYOC promoter which contains a critical cluster of four retinoic acid responsive (Montrer GPRC5A Kits ELISA) elements (RAREs), with the RARE-DR2 presenting the strongest effect and binding the RARalpha (Montrer RARA Kits ELISA)/RXRalpha (Montrer RXRA Kits ELISA) heterodimer.

  7. Five out of 30 families with PCG (16.7%) had disease attributable to CYP1B1 (Montrer CYP1B1 Kits ELISA) alterations suggesting that CYP1B1 (Montrer CYP1B1 Kits ELISA) is not the major gene causing PCG in Vietnamese unlike in the case of Arab or Romany patients.

  8. The present study provides insight into the genetic or haplotype variants of MYOC and OPTN (Montrer OPTN Kits ELISA) genes contributing to primary glaucoma. Haplotype variants identified in the present study may be regarded as potential contributing factors of primary glaucoma in Korea.

  9. Familial linkage studies for primary angle-closure glaucoma have been performed and identified MYOC causative primary angle-closure glaucoma disease

  10. The rate of CYP1B1 (Montrer CYP1B1 Kits ELISA) mutations in Lebanese patients with primary congenital glaucoma (PCG) is lower than that reported in other Arab and Middle Eastern populations and suggests other genes are responsible.

Cow (Bovine) Myocilin (MYOC) interaction partners

  1. endoproteolytic processing might regulate the activity of myocilin; the inhibition of the processing by pathogenic mutations impairs the normal role of myocilin

Myocilin (MYOC) profil antigène

Antigen Summary

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Gene names and symbols associated with Myocilin (MYOC) Kits ELISA

  • myocilin (MYOC) anticorps
  • myocilin (myoc) anticorps
  • myocilin (Myoc) anticorps
  • AI957332 anticorps
  • GLC1A anticorps
  • GPOA anticorps
  • JOAG anticorps
  • JOAG1 anticorps
  • MGC136645 anticorps
  • MYOC anticorps
  • myocilin anticorps
  • Tigr anticorps
  • zgc:136645 anticorps

Protein level used designations for Myocilin (MYOC) Kits ELISA

myocilin , trabecular meshwork-induced glucocorticoid response protein , mutated trabecular meshwork-induced glucocorticoid response protein

GENE ID SPECIES
397046 Sus scrofa
548602 Danio rerio
704406 Macaca mulatta
17926 Mus musculus
4653 Homo sapiens
81523 Rattus norvegicus
281342 Bos taurus
101087632 Felis catus
490344 Canis lupus familiaris
100008897 Oryctolagus cuniculus
Avez-vous cherché autre chose?