anti-Myoferlin (MYOF) Anticorps

Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. De plus, nous expédions Myoferlin Kits (6) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MYOF 26509 Q9NZM1
MYOF 226101 Q69ZN7
MYOF 309499  
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Top anti-Myoferlin Anticorps sur anticorps-enligne.fr

Showing 10 out of 19 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host:  Rabbit  Target Name:  MYOF  Sample Type:  Human Fetal Brain  Antibody Dilution:  1.0ug/ml Host:  Rabbit  Target Name:  MYOF  Sample Type:  Human Fetal Heart  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
$319.00
Détails
Humain Lapin Inconjugué WB 100 μL 11 to 14 Days
$581.17
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), IP, WB Anti-MYOF / Myoferlin antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μL 11 to 14 Days
$639.83
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cell lines, using MYOF antibody. 100 μL 6 to 11 Days
$390.55
Détails
Humain Souris Inconjugué ELISA, IHC, WB   100 μg 6 to 7 Days
$503.06
Détails
Humain Souris Inconjugué ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . FER1L3 polyclonal antibody (A01), Lot # 060529JCS1. Western Blot analysis of FER1L3 expression in human stomach. 50 μL 11 to 12 Days
$305.71
Détails
Humain Lapin Inconjugué WB FER1L3 antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Détails
Humain Souris Inconjugué IHC, WB   100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué IF, IHC, WB   100 μL 11 to 16 Days
$743.29
Détails
Humain Lapin Inconjugué ELISA, IF/ICC, IHC, WB   50 μL 11 to 16 Days
$443.20
Détails

anti-Myoferlin Anticorps mieux référencés

  1. Human Polyclonal MYOF Primary Antibody pour ICC, IF - ABIN4337241 : Volakis, Li, Ackerman, Mihai, Bechel, Summerfield, Ahn, Powell, Zielinski, Rosol, Ghadiali, Kniss: Loss of myoferlin redirects breast cancer cell motility towards collective migration. dans PLoS ONE 2014 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre Myoferlin partenaires d’interaction

Human Myoferlin (MYOF) interaction partners

  1. Myoferlin hyperexpression can be a useful marker for predicting the development of subsequent primary malignancies in patients with ccRCC.

  2. Data show that myoferlin (MYOF) plays an important role in VM and knockdown of MYOF suppresses vasculogenic mimicry (VM) formation via decreasing matrix metallopeptidase 2 (MMP-2) and inducing mesenchymal-to-epithelial transition (MET) in A375 melanoma cells.

  3. Results show that the FerA domain is a novel four-helix bundle fold with its own Ca(2+)-dependent phospholipid-binding activity which interaction with the membrane is enhanced by the presence of Ca(2+).

  4. The observed mitochondrial fission induced by myoferlin depletion led to a decrease of cell proliferation.

  5. Myoferlin is a general component of cancer cell derived exosomes from different breast and pancreatic cancer cell lines.

  6. the cleavage of myoferlin, yielding a membrane-associated dual C2 domain 'mini-myoferlin', is reported.

  7. A novel regulator, myoferlin, of ADAM12 is discovered in HeLa cells and this protein increases ADAM12 expression level, stability, and its enzymatic activity, leading to the reduction of its substrate, E-cadherin, which plays important roles in the regulation of cell adhesion and tumor metastasis.

  8. Data show myoferlin depletion did not affect STAT3 transcription factor (STAT3) phosphorylation, but completely blocked STAT3 translocation to nucleus.

  9. This study is the first to report robust age associations for DNA methylation in MYOF and DDO, both of which have plausible functional roles in aging

  10. Results demonstrate for the first time that nuclear myoferlin expression independently predicts poor clinical outcome in OPSCC patients.

  11. Myoferlin plays a key role in VEGFA secretion and impacts tumor-associated angiogenesis in human pancreas cancer.

  12. MYOF regulates cell adhesions and cell-substrate adhesion strength and may account for the high degree of motility in invasive breast cancer cells.

  13. These data provide the first evidence of myoferlin expression in solid human and mouse tumors.

  14. Data indicate that dysferlin, otoferlin, and myoferlin do not merely passively adsorb to membranes but actively sculpt lipid bilayers.

  15. High myoferlin expression is associated with breast cancer.

  16. The effect of myoferlin on the expression of ZO-1 in airway epithelial cells indicates its role in membrane fusion events that regulate cell detachment and apoptosis within the airway epithelium.

  17. suggest a novel role of MYOF in breast tumor cell invasion and a potential reversion to an epithelial phenotype upon loss of MYOF

  18. MYOF plays a previously unrecognized role in cancer cell invasion.

  19. myoferlin forms a complex with dynamin-2 and VEGFR-2, which prevents CBL-dependent VEGFR-2 polyubiquitination and proteasomal degradation.

  20. solution structure of the inner DysF domain of the dysferlin paralogue myoferlin, which has a unique fold held together by stacking of arginine and tryptophans, mutations that lead to clinical disease in dysferlin

Mouse (Murine) Myoferlin (MYOF) interaction partners

  1. data demonstrate myoferlin's critical role in lysosomal exocytosis by phagocytes

  2. these findings demonstrate the importance of dysferlin and myoferlin for transverse tubule function and in the genesis of muscular dystrophy.

  3. These data provide the first evidence of myoferlin expression in solid human and mouse tumors.

  4. Myoferlin gene knockdown not only decreases lipid vesicle fusion in EC but also attenuates Vascular Endothelial Growth Factor (VEGF) Receptor-2 (VEGFR-2) expression.

  5. increased expression in myofibres after muscle injury and in a mouse model of muscular dystrophy

  6. IGF1 receptor recycling is required for normal myogenesis and myoferlin is a critical mediator of postnatal muscle growth mediated by IGF1

  7. Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains. (myoferlin)

  8. myoferlin plays role in the maturation of myotubes and the formation of large myotubes that arise from the fusion of myoblasts to multinucleate myotubes.

  9. myoferlin forms a complex with dynamin-2 and VEGFR-2, which prevents CBL-dependent VEGFR-2 polyubiquitination and proteasomal degradation.

  10. interaction of myoferlin with EHD2 identifies molecular overlap between the endocytic recycling pathway and the machinery that regulates myoblast membrane fusion

Myoferlin (MYOF) profil antigène

Profil protéine

Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

Gene names and symbols associated with anti-Myoferlin (MYOF) Anticorps

  • myoferlin (MYOF) anticorps
  • myoferlin (Myof) anticorps
  • myoferlin (myof) anticorps
  • myoferlin (LOC100380767) anticorps
  • 2310004N10Rik anticorps
  • 2310051D19Rik anticorps
  • E030042N20Rik anticorps
  • fer1l3 anticorps
  • RGD1564216 anticorps
  • zgc:63504 anticorps

Protein level used designations for anti-Myoferlin (MYOF) Anticorps

fer-1-like 3, myoferlin , fer-1-like protein 3 , myoferlin , Fer-1-like protein 3

GENE ID SPECIES
26509 Homo sapiens
226101 Mus musculus
309499 Rattus norvegicus
393849 Danio rerio
513597 Bos taurus
607472 Canis lupus familiaris
700922 Macaca mulatta
100037837 Xenopus (Silurana) tropicalis
100154898 Sus scrofa
100380767 Salmo salar
100484247 Ailuropoda melanoleuca
100541976 Meleagris gallopavo
100595205 Nomascus leucogenys
423805 Gallus gallus
100071199 Equus caballus
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