anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) Anticorps

The protein encoded by MARCKS is a substrate for protein kinase C. De plus, nous expédions MARCKS Kits (21) et MARCKS Protéines (9) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MARCKS 17118 P26645
MARCKS 25603  
MARCKS 4082 P29966
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Top anti-MARCKS Anticorps sur anticorps-enligne.fr

Showing 10 out of 258 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Sample: SH-SY5Y cells 2.0x105 cellsPrimary dilution: 1:2500Secondary Antibody: HRP-conjugated goat anti-rabbit IgGSecondary dilution: 1:5000Image Submitted by:Atsuhiro TanabePharma Sci Kitasato University 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$484.00
Détails
Poulet Lapin Inconjugué IP, WB Western blot analysis of MARCKS expression in HeLa (A), RAW264.7 (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Poulet Lapin Inconjugué WB Western blot analysis of MARCKS (pS163) expression in MCF7 PMA-treated (A), SP2/0 PMA-treated (B), PC12 PMA-treated (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$575.00
Détails
Humain Lapin Inconjugué IF, ELISA, WB Western blot analysis of extracts from Jurkat cells, using MARCKS (Ab-158) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using MARCKS (Ab-158) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of hMARCKS-K254 (ABIN389097) in Hela cell line lysates (35 µg/lane). MARCKS (arrow) was detected using the purified polyclonal antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from K562 cells treated with EGF 200ng/ml 30', using MARCKS (Phospho-Ser158) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells, treated with LPS 100ng/ml 30', using MARCKS (Ab-163) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MARCKS (Ab-163) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using MARCKS (Phospho-Ser163) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails

anti-MARCKS Anticorps mieux référencés

  1. Chinese Hamster Polyclonal MARCKS Primary Antibody pour WB - ABIN152966 : Zhang, Ahmed, McFarlane, Capone, Boreham, Truant, Igdoura, Trigatti: Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways. dans Journal of lipid research 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human MARCKS Primary Antibody pour IHC - ABIN966535 : Pariser, Herradon, Ezquerra, Perez-Pinera, Deuel: Pleiotrophin regulates serine phosphorylation and the cellular distribution of beta-adducin through activation of protein kinase C. dans Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

  3. Human Polyclonal MARCKS Primary Antibody pour IF, WB - ABIN362996 : Litherland, Elias, Hui, Macdonald, Catterall, Barter, Farren, Jefferson, Rowan: Protein kinase C isoforms zeta and iota mediate collagenase expression and cartilage destruction via STAT3- and ERK-dependent c-fos induction. dans The Journal of biological chemistry 2010 (PubMed)
    Show all 5 Pubmed References

  4. Human Polyclonal MARCKS Primary Antibody pour ELISA - ABIN545290 : Rao, Murty, Gaidano, Hauptschein, Dalla-Favera, Chaganti: Subregional mapping of 8 single copy loci to chromosome 6 by fluorescence in situ hybridization. dans Cytogenetics and cell genetics 1994 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal MARCKS Primary Antibody pour IF, WB - ABIN6713001 : Li, Li, Li, Zhong, Chen, Zhang, Hu, Shen: miR-21 as an independent biochemical recurrence predictor and potential therapeutic target for prostate cancer. dans The Journal of urology 2013 (PubMed)

Plus d’anticorps contre MARCKS partenaires d’interaction

Xenopus laevis Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. The results indicated MARCKS may be the missing link in the regulation of the function (i.e., sodium transport) of epithelial sodium channels by anionic phospholipids.

Mouse (Murine) Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. Study in mice reports that Marcks is regulated by acetylation through Tip60 and Sirt2. Maternal diabetes-induced MARCKS acetylation is required for its phosphorylation, which disables the protective effects of MARCKS on mitochondria and the endoplasmic reticulum, leading to cellular organelle stress and neural tube defect formation.

  2. this work establishes a novel role for MARCKS in axon dynamics and highlights the necessity of MARCKS as an organizer of DCC signaling at the membrane.

  3. Strongly support the existence of a PKC-MARCKS-PI3K regulatory module.

  4. ENaC activity is regulated by calpain-2 proteolysis of MARCKS.

  5. In the absence of Pin1, MARCKS is hyper-phosphorylated, leading to loss of cell adhesions, and collapse of the growth cone.

  6. Findings suggest that MIR429 modulates mucin secretion in human colorectal cells and mouse colitis tissues by up-regulating of MARCKS expression.

  7. Conditional deletion of MARCKS in ECs induces intracellular accumulation of mucins, elevated oxidative stress, and lipid droplet buildup.

  8. MARCKS acts as a "molecular switch," binding to and regulating PIP2 signaling to regulate processes like proplatelet extension (microtubule-driven) vs proplatelet branching (Arp2/3 and actin polymerization-driven).

  9. MARCKS knockdown arrested VSMC cell cycle by decreasing KIS expression. Decreased KIS expression resulted in nuclear trapping of p27kip1 in VSMCs.

  10. MARCKS regulates the expression of proinflammatory cytokines in macrophages through activation of p38/JNK MAPK and NF-kappaB.

  11. Targeting phospho-MARCKS overcomes drug-resistance and induces antitumor activity in preclinical models of multiple myeloma.

  12. Grin 1 is identified as a novel Cdk5 substrate and MARCKS is confirmed as a Cdk5 substrate.

  13. MARCKS appears to be a nonessential regulatory protein in mast cell exocytosis but exerts a negative modulation.

  14. MARCKS overexpression in the hippocampus of old mice leads to long-term potentiation and improved memory.

  15. an important functional role for the interaction between MARCKS and PSA in the developing and adult nervous system.

  16. cathepsin K exocytosis is controlled by PKCdelta through modulation of the actin bundling protein myristoylated alanine-rich C-kinase substrate.

  17. These results suggest that MARCKS is involved in directed migration of macrophages

  18. a critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically dependent on MARCKS, Rac1, and c-Abl.

  19. the capacity of MARCKS-ED to regulate granule exocytosis in a PKC-dependent manner, consistent with regulated sequestration of phosphoinositides that mediate granule fusion at the plasma membrane.

  20. MARCKS contributes to the negative regulation of the cellular response to LPS.

Zebrafish Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. Marcksb is required for proper gastrulation movements of zebrafish.

Human Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. MARCKS is a putative target for drug design.

  2. High MARCKS expression is associated with liver tumor.

  3. Raman spectra show vibrational bands of Phenylalanine and Lysine residues specific for the protein effector domain, and evidence the presence of alpha helix structure in both configurations.

  4. tromal MARCKS overexpression in tumors might contribute to cancer-associated fibroblasts activation and to the poor prognosis of Epithelial ovarian cancer.

  5. Study identifies MARCKS phosphorylation at Ser46 is a hallmark of neurite degeneration, the classical hallmark of Alzheimer's disease (AD) pathology. MARCKS phosphorylation is induced by HMGB1 via TLR4.

  6. we propose a role for MARCKS in a novel mechanism of BTZ resistance via exocytosis of ubiquitinated proteins in BTZ-resistant cells leading to quenching of proteolytic stress.

  7. MARCKS overexpression might in part explain the poor prognosis of inflammatory breast cancer.

  8. Authors determined that myristoylated alanine-rich C-kinase substrate (MARCKS) was highly expressed in ovarian stroma, and was required for the differentiation and tumor promoting function of CAFs.

  9. Data indicate MARCKS (myristoylated alanine-rich C-kinase substrate) as a target of miR-21.

  10. data suggest a major contribution of MARCKS to kidney cancer growth and provide an alternative therapeutic strategy of improving the efficacy of multikinase inhibitors.

  11. These data suggested that miR34c3p acts as a tumor suppressor via regulation of MARCKS expression in OS progression

  12. Ca(2+)-PKC-MARCKS-PIP2-PI3K-PIP3 system functions as an activation module in vitro

  13. Findings show that calmodulin (CaM) stimulates phosphoinositide-3-kinase (PI3K) lipid kinase activity by binding MARCKS and displacing it from phosphatidylinositol 4,5-bisphosphate (PIP2) headgroups, thereby releasing free PIP2 that recruits active PI3K to the membrane and serves as the substrate for the generation of phosphatidylinositol 3,4,5-trisphosphate (PIP3).

  14. Findings suggest that MIR429 modulates mucin secretion in human colorectal cells and mouse colitis tissues by up-regulating of MARCKS expression.

  15. Knockdown of MARCKS in HepG2 cells reduced cell migration and invasion, but not cell proliferation.

  16. MARCKS upregulation increases vascular smooth muscle cell motility by activation of Rac1 and Cdc42, promoting neointima formation.

  17. A novel role for MARCKS in regulating nuclear functions such as gene expression.

  18. MARCKS knockdown arrested VSMC cell cycle by decreasing KIS expression. Decreased KIS expression resulted in nuclear trapping of p27kip1 in VSMCs.

  19. unresponsiveness of breast cancer to paclitaxel treatment is, at least in part, mediated by phospho-MARCKS

  20. MARCKS and PPP1R9A might contribute to spine loss in schizophrenia and bipolar disorder through their interactions.

Cow (Bovine) Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. MARCKS protein mediates hydrogen peroxide regulation of endothelial permeability.

  2. a critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically dependent on MARCKS, Rac1, and c-Abl.

  3. These findings demonstrate a critical role for MARCKS-phosphatidylinositol-4,5-diphosphate signaling in regulating dendrite development.

  4. Protein kinase C mediated inhibition of endothelial L-arginine transport is mediated by MARCKS protein

MARCKS profil antigène

Profil protéine

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Gene names and symbols associated with MARCKS

  • myristoylated alanine-rich protein kinase C substrate (marcks) anticorps
  • myristoylated alanine rich protein kinase C substrate (MARCKS) anticorps
  • methyl binding domain106 (mbd106) anticorps
  • myristoylated alanine-rich protein kinase C substrate S homeolog (marcks.S) anticorps
  • myristoylated alanine rich protein kinase C substrate (Marcks) anticorps
  • myristoylated alanine-rich protein kinase C substrate b (marcksb) anticorps
  • 80K-L anticorps
  • KINC anticorps
  • MACS anticorps
  • MARCKS anticorps
  • MGC89127 anticorps
  • PKCSL anticorps
  • PRKCSL anticorps
  • wu:fb55c06 anticorps
  • wu:fb92d04 anticorps
  • wu:fc19b04 anticorps
  • wu:fc44a10 anticorps
  • zgc:110235 anticorps

Protein level used designations for MARCKS

myristoylated alanine-rich protein kinase C substrate , methyl binding domain , Zmmbd2 , PCO124731 , PCO124731_ov , myristoylated alanine-rich C-kinase substrate , Myristoylated alanine-rich protein kinase C substrate , protein kinase C substrate 80 kDa protein , myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) , phosphomyristin , protein kinase C substrate, 80 kDa protein, light chain , myristoylated alanine-rich C kinase substrate (MARCKS) , ACAMP-81

GENE ID SPECIES
448317 Xenopus (Silurana) tropicalis
694077 Macaca mulatta
742020 Pan troglodytes
100345174 Oryctolagus cuniculus
542069 Zea mays
379767 Xenopus laevis
17118 Mus musculus
25603 Rattus norvegicus
323201 Danio rerio
4082 Homo sapiens
396473 Gallus gallus
613548 Bos taurus
612436 Canis lupus familiaris
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