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Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal) acetyltransferase activity (By similarity). De plus, nous expédions NAA50 Protéines (9) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal NAA50 Primary Antibody pour IHC, WB - ABIN4893405
Mughal, Grieg, Skjellegrind, Fayzullin, Lamkhannat, Joel, Ahmed, Murrell, Vik-Mo, Langmoen, Stangeland: Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells. dans Molecular cancer 2015
Show all 2 Pubmed References
Because Naa10 (Montrer ARD1A Anticorps) is reported to acetylate all amino termini that are devoid of methionine and Naa50 acetylates all other peptides that are followed by methionine
co-depletion of NatA, a heterodimeric NAT (Montrer BRD2 Anticorps) complex that physically interacts with Naa50, rescues the sister-chromatid cohesion defects and the resulting mitotic arrest caused by Naa50 depletion, indicating that NatA and Naa50 play antagonistic roles in cohesion.
The study quantitatively compared the Nt-acetylomes of wild-type yeast S. cerevisiae expressing the endogenous yeast Naa50 (yNaa50), the congenic strain lacking yNaa50, and an otherwise identical strain expressing human Naa50 (hNaa50).
Development of the first N-terminal acetyltransferase (Montrer NAA15 Anticorps) (NAT (Montrer BRD2 Anticorps)) inhibitors, including a specific Naa50 inhibitor.
The first description of the human homologue of Nat5p/San, hNAT5, the third component of the human NatA N-alpha-acetyltransferase complex
Nat5 displays both protein N alpha- and N epsilon-acetyltransferase activity.
Human protein N-terminal acetyltransferase (Montrer NAA15 Anticorps) hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study.
Naa50p can accommodate only an alpha-amino substrate and not a side chain lysine substrate that is acetylated by lysine acetyltransferase enzymes such as Gcn5.
Data show that with MAK3 (Montrer NAA30 Anticorps) knockdown, p53 (Montrer TP53 Anticorps) is stabilized and phosphorylated and there is a significant transcriptional activation of proapoptotic genes downstream of p53 (Montrer TP53 Anticorps), and that localization of Arl8b (Montrer ARL8B Anticorps) is altered, suggesting that Arl8b (Montrer ARL8B Anticorps) is a Mak3 (Montrer NAA30 Anticorps) substrate.
Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal) acetyltransferase activity (By similarity).
, N-acetyltransferase 13 (GCN5-related)
, N-acetyltransferase 5
, N-acetyltransferase san homolog
, N-alpha-acetyltransferase 50
, N-alpha-acetyltransferase 50, NatE catalytic subunit
, natE catalytic subunit
, separation anxiety
, Mak3p homolog
, N-acetyltransferase 13
, N-acetyltransferase NAT13
, Nalpha acetyltransferase 50