N-Myc (And STAT) Interactor (NMI) Kits ELISA

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. De plus, nous expédions NMI Anticorps (54) et NMI Protéines (9) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
NMI 9111 Q13287
NMI 64685 O35309
Anti-Rat NMI NMI 311021  
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 5.8 pg/mL 23.5-1500 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 15 to 18 Days
$788.33
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Souris 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 15 to 18 Days
$788.33
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Boeuf (Vache)
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$1,029.60
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NMI Kits ELISA mieux référencés

  1. Human NMI Kit ELISA pour Sandwich ELISA - ABIN845614 : Xiahou, Wang, Shen, Zhu, Xu, Hu, Guo, Li, Tian, Liu, Liang: NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury. dans Nature communications 2018 (PubMed)

Plus Kits ELISA pour NMI partenaires d'interaction

Human N-Myc (And STAT) Interactor (NMI) interaction partners

  1. NMI and RAC1 might represent two new key genes related to gastric cancer

  2. Nmi has a distinct role in the differentiation process of mammary luminal epithelial cell compartment and developmental aberrations resulting from Nmi absence contribute to metastasis.

  3. These results revealed that IRF-1 is involved in the IFN-inducible expression of Nmi.

  4. Our study showed that NMI suppressed tumor growth by inhibiting PI3K/AKT, MMP2/MMP9, COX-2/PGE2 signaling pathways and p300-mediated NF-kappaB acetylation, and predicted a favorable prognosis in human lung adenocarcinomas, suggesting that NMI was a potential tumor suppressor in lung cancer.

  5. results provide new insights into understanding the regulatory mechanism of cancer stem cells and suggest that the NMI-YY1-hTERT signaling axis may be a potential therapeutic target for breast cancers.

  6. Damage-associated molecular patterns (DAMP) are important mediators of innate immunity. Here the authors show that N-myc and STAT interactor (NMI) and interferon-induced protein 35 (IFP35) act as DAMPs to promote inflammation by activating macrophages via the Toll-like receptor 4 and NF-kappaB pathways.

  7. These investigations demonstrated etoposide-induced NMI can suppress tumor proliferation and promote cell apoptosis by activating the ARF-p53 signaling pathway in lung carcinoma. Our results provide an alternative mechanism for etoposide in lung carcinoma and suggest NMI has a critical role in suppressing lung carcinoma progression.

  8. Data suggest that N-myc (and STAT) interactor (NMI) could improve its downstream target bradykinin B2 receptor (BDKRB2) expression to induce extracellular signal-regulated kinases (ERK) 1/2 activation, and thereby further evoke malignant progression of hepatocellular carcinoma (HCC).

  9. N-Myc-interacting protein (NMI) negatively regulates epithelial-mesenchymal transition by inhibiting the acetylation of NF-kappaB/p65 in histone deacetylase-dependent manner.

  10. N-myc and STAT interactor sensitizes breast cancer cells to cisplatin treatment through DRAM1 dependent autophagy.

  11. Results show that aberrant miR-29 expression may account for reduced NMI expression in breast tumors and mesenchymal phenotype of cancer cells that promotes invasive growth.

  12. The results showed that SARS coronavirus protein 6 can promote the ubiquitin-dependent proteosomal degradation of Nmi.

  13. overexpression or depletion of NMI revealed its regulation on G1/S progression and cell proliferation (both in vitro and in vivo), and this effect was partially dependent on STAT1, which interacted with and was regulated by NMI.

  14. Trim21 regulates Nmi-IFI35 complex-mediated inhibition of innate antiviral response

  15. Its potential function in transcriptional activation of NMI.

  16. identified NMI induction as a novel negative feedback mechanism that decreases IRE1alpha-dependent activation of JNK and apoptosis in cytokine-exposed beta cells

  17. Thus our work reveals a novel NMI-mediated, transcription-independent ARF induction pathway in response to cellular stresses.

  18. Dissociation of the IFN-induced protein NMI from IFP35 is a newly defined specific cytoplasmic event occurring during apoptosis.

  19. complex with BRCA1 and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene promoter activity in breast cancer

  20. Apoptin mutant T1 still interacted with Nmi, suggesting that its C-terminal 11 AA was not essential for the interaction.

Mouse (Murine) N-Myc (And STAT) Interactor (NMI) interaction partners

  1. Nmi has a distinct role in the differentiation process of mammary luminal epithelial cell compartment and developmental aberrations resulting from Nmi absence contribute to metastasis.

  2. Damage-associated molecular patterns (DAMP) are important mediators of innate immunity. Here the authors show that N-myc and STAT interactor (NMI) and interferon-induced protein 35 (IFP35) act as DAMPs to promote inflammation by activating macrophages via the Toll-like receptor 4 and NF-kappaB pathways.

  3. These findings suggest that Nmi is a negative regulator of the virus-triggered induction of type I IFNs that targets IRF7

NMI profil antigène

Antigen Summary

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.

Gene names and symbols associated with NMI

  • N-myc and STAT interactor (NMI) anticorps
  • N-myc (and STAT) interactor (Nmi) anticorps
  • N-myc (and STAT) interactor (nmi) anticorps
  • N-myc and STAT interactor L homeolog (nmi.L) anticorps
  • N-myc and STAT interactor (nmi) anticorps
  • N-myc and STAT interactor (Nmi) anticorps
  • fj02e01 anticorps
  • MGC108489 anticorps
  • NMI anticorps
  • wu:fj02e01 anticorps

Protein level used designations for NMI

N-myc interactor , N-myc-interactor , N-mcy (and STAT) interactor , N-myc (and STAT) interactor , N-myc and STAT interactor , N-myc/STAT interactor

GENE ID SPECIES
9111 Homo sapiens
64685 Mus musculus
311021 Rattus norvegicus
335331 Danio rerio
424314 Gallus gallus
470714 Pan troglodytes
476146 Canis lupus familiaris
495484 Xenopus laevis
511280 Bos taurus
613094 Xenopus (Silurana) tropicalis
694554 Macaca mulatta
100724801 Cavia porcellus
100050154 Equus caballus
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