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The protein encoded by NDUFB6 is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I).
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Human Polyclonal NDUFB6 Primary Antibody pour ICC, IF - ABIN4338396
Desmurs, Foti, Raemy, Vaz, Martinou, Bairoch, Lane: C11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilization. dans Molecular and cellular biology 2015
we propose that NDUFB6 is a possible tumor suppressor of metastatic ccRCCs.
NDUFS6 (Montrer NDUFS6 Anticorps) has a Zn-binding site and is essential for biogenesis of mitochondrial complex I
NDUFB6 subunit is required for complex I activity.
Results demonstrate that genetic, epigenetic, and nongenetic factors associate with NDUFB6 expression in human muscle and suggest that genetic and epigenetic factors may interact to increase age-dependent susceptibility to insulin (Montrer INS Anticorps) resistance.
Polymorphism in the NDUFB6 gene from respiratory chain complex I related to ATP synthesis and insulin (Montrer INS Anticorps) sensitivity response to exercise training found in relatives of humans with type 2 diabetes.
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified.
, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6
, NADH-ubiquinone oxidoreductase B17 subunit
, complex I-B17
, NADH-ubiquinone oxidoreductase beta subunit, 6
, complex I, mitochondrial respiratory chain, B17 subunit
, Complex I-B17
, mitochondrial complex I subunit NDUFB6