NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa Protéines (NDUFV2)

The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. De plus, nous expédions NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa Anticorps (100) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
NDUFV2 4729 P19404
NDUFV2 72900 Q9D6J6
NDUFV2 81728 P19234
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Top NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa Protéines sur anticorps-enligne.fr

Showing 10 out of 12 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Détails
Escherichia coli (E. coli) Humain GST tag NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2) (AA 35-249), (partial) protein (GST tag) 1 mg 60 to 71 Days
$1,842.50
Détails
Wheat germ Humain GST tag 10 μg 11 to 12 Days
$340.00
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Détails
Escherichia coli (E. coli) Humain His tag 100 μg 13 to 16 Days
$553.85
Détails
Levure Boeuf (Vache) His tag   1 mg 60 to 71 Days
$2,539.17
Détails
Levure Rat His tag   1 mg 60 to 71 Days
$2,539.17
Détails
Levure Pongo pygmaeus His tag   1 mg 60 to 71 Days
$2,539.17
Détails
Levure Chimpanzé His tag   1 mg 60 to 71 Days
$2,539.17
Détails

NDUFV2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Plus protéines pour NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2) partenaires d'interaction

Human NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2) interaction partners

  1. haplotype T-C consisting of rs12457810 and rs12964485 in the 5'-upstream region of NDUFV2 may be a protective factor for the development of MDD in Han Chinese

  2. We have identified NDUFV2 mutations in two families with Complex I deficiency, including a novel mutation.

  3. The results show mitochondrial haplotypes associated with polymorphism of this gene are associated with elite middle and sprint power endurance in Japanese athletes

  4. There is no statistical significance between NDUFV2 gene promoter variants and susceptibility to schizophrenia in Han Chinese.

  5. The mitochondrial targeting sequence of NDUFV2 is located at the N-terminus of the precursor protein. Impairment of mitochondrial localization of NDUFV2 as a mechanistic basis for early-onset hypertrophic cardiomyopathy and encephalopathy was established.

  6. Three single nucleotide polymorphisms in the NDUFV2 gene, were studies in bipolar disorder pateints and controls.

  7. Our findings suggest further studies addressing the role of NDUFV2 variation in Parkinson's disease may be warranted.

  8. Sp1 was abnormally expressed in schizophrenia and its mRNA alteration pattern paralleled that of NDUFV1 and NDUFV2 in schizophrenic patients.

  9. mutation causes early onset hypertrophic cardiomyopathy and encephalopathy

  10. Polymorphisms of this gene may be one of the genetic risk factors for bipolar disorder.

  11. Polymorphisms in the promoter region of NDUFV2 are a genetic risk factor for bipolar disorder. The association of the haplotypes -602G> A and -3542G> A polymorphisms with bipolar disorder was seen both in Japanese case-control samples and NIMH trios.

  12. NDUFV2 individual genotypes were not associated with schizophrenia, but the haplotype consisting of the two single nucleotide polymorphisms were significantly associated with schizophrenia.

  13. genetic variants of NDUFV2 may increase risk for bipolar disorder.

  14. This study found that the expressions of NDUFV2 were up-regulated in those from patients with Japanese bipolar II disorder and the mRNA levels of this gene were down-regulated in Caucasian schizophrenia.

  15. Data show that the haplotype consisting of rs6506640 (-342G > A) and rs906807 (86C > T) on the mitochondrial gene NDUFV2 is found to be associated with bipolar disorder.

  16. Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.

  17. This protein has been found differentially expressed in the temporal lobe from patients with schizophrenia.

Mouse (Murine) NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2) interaction partners

  1. The results of this study indicated that ndufv2 knockdown influences the actin cytoskeleton and tubulin stabilization in the leading process of migrating cortical neurons

  2. The authors biochemically separate the NADH dehydrogenase module from complex I of bovine heart into subunit I, II and III fractions. Subunit II fraction, also known as the NADH dehydrogenase (ubiquinone) flavoprotein 2 protein, has a molecular weight of 24 000 Da and contains an iron-sulfur center.

  3. The authors use green fluorescent-tagged complex I subunits to determine the kinetics of assembly. Tagged human NDUFV2 can replace the endogenous protein in the holo-complex I protein and was also found in complex I subassemblies, suggesting that NDUFV2 may directly incorporate into the holo-enzyme and may also assemble into smaller complexes or in a monomer pool.

  4. The authors provide an overview of the function and assembly of human complex I, also known as NADH dehydrogenase (ubiquinone) 1 alpha subcomplex. They discuss its role in oxidative phosphorylation and the implications of complex I deficiency in disease.

Cow (Bovine) NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2) interaction partners

  1. Data show that during NADH-ubiquinone oxidoreductase (Complex I) catalytic electron transfer from NADH to DBQ, the superoxide generation site was mostly shifted to the SQ.

  2. Data suggest that Q(Nf) plays a role in a "direct" redox-driven proton pump, while Q(Ns) triggers an "indirect" conformation-driven proton pump in NADH-ubiquinone oxidoreductase (complex I).

  3. The catalytic function of NDH in the mediation of superoxide generation was investigated by EPR spin-trapping.

Profil protéine NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2)

Profil protéine

The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19.

Gene names and symbols associated with NDUFV2

  • NADH:ubiquinone oxidoreductase core subunit V2 (NDUFV2)
  • NADH dehydrogenase (ubiquinone) flavoprotein 2 (Ndufv2)
  • NADH:ubiquinone oxidoreductase core subunit V2 (Ndufv2)
  • NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (LOC409793)
  • NADH:ubiquinone oxidoreductase core subunit V2 (ndufv2)
  • NADH dehydrogenase (ubiquinone) flavoprotein 2 (LOC657790)
  • NADH dehydrogenase (ndufv2)
  • NADH dehydrogenase [ubiquinone] flavoprotein 2,mitochondrial (NDUFV2)
  • NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa (Ndufv2)
  • NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa (NDUFV2)
  • NADH dehydrogenase (ubiquinone) flavoprotein 2 (ndufv2)
  • 2900010C23Rik Protéine
  • CI-24k Protéine
  • DDBDRAFT_0189294 Protéine
  • DDBDRAFT_0233206 Protéine
  • DDB_0189294 Protéine
  • DDB_0233206 Protéine
  • GB17038 Protéine
  • NuoE Protéine
  • zgc:73198 Protéine

Protein level used designations for NDUFV2

NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial , NADH dehydrogenase ubiquinone flavoprotein 2, mitochondrial , NADH-ubiquinone oxidoreductase 24 kDa subunit , NADH-ubiquinone oxidoreductase flavoprotein 2 , complex I 24kDa subunit , complex I, mitochondrial respitory chain, 24 kD subunit , nuclear-encoded mitochondrial NADH-ubiquinone reductase 24Kd subunit , 24-kDa subunit of mitochondrial NADH dehydrogenase , NADH dehydrogenase flavoprotein 2 , NADH dehydrogenase subunit II , NADH-ubiquinone reductase 24 kDa mitochondrial , NADH dehydrogenase ubiquinone flavoprotein 2 , GLEAN_03690 , NADH dehydrogenase [ubiquinone] flavoprotein 2,mitochondrial , OXPHOS complex I 24 kDa subunit , NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa , NADH dehydrogenase flavoprotein 2, 24kDa

GENE ID SPECIES
4729 Homo sapiens
72900 Mus musculus
81728 Rattus norvegicus
282290 Bos taurus
409793 Apis mellifera
426488 Gallus gallus
455295 Pan troglodytes
480204 Canis lupus familiaris
549920 Xenopus (Silurana) tropicalis
657790 Tribolium castaneum
706067 Macaca mulatta
8628028 Dictyostelium discoideum AX4
10865442 Parachlamydia acanthamoebae UV-7
100037991 Sus scrofa
100115243 Nasonia vitripennis
100137466 Papio anubis
393720 Danio rerio
100719197 Cavia porcellus
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