NEL-Like 2 (Chicken) Protéines (NELL2)

The protein encoded by NELL2 is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. De plus, nous expédions NELL2 Anticorps (53) et NELL2 Kits (6) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
NELL2 54003  
NELL2 4753 Q99435
NELL2 81734  
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Top NELL2 Protéines sur anticorps-enligne.fr

Showing 8 out of 9 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,741.67
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,741.67
Détails
Baculovirus infected Insect Cells Humain His tag 50 μg Connectez-vous pour afficher 14 to 16 Days
$440.65
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 11 Days
$888.80
Détails
Escherichia coli (E. coli) Souris His tag 0.05 mg Connectez-vous pour afficher 2 to 3 Days
$309.38
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$340.00
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$4,334.00
Détails
Escherichia coli (E. coli) Humain S tag,His tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$685.00
Détails

NELL2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine) ,

Human , , , ,
, , ,
Rat (Rattus)

Plus protéines pour NEL-Like 2 (Chicken) (NELL2) partenaires d'interaction

Mouse (Murine) NEL-Like 2 (Chicken) (NELL2) interaction partners

  1. Cytosolic NELL2 specifically interacts with PKC beta isotypes and inhibits PKC beta1 through direct binding to the N-terminal pseudosubstrate domain of PKC beta1.

  2. These findings identify NELL2 as an axon guidance cue and establish Robo3 as a multifunctional regulator of pathfinding that simultaneously mediates NELL2 repulsion, inhibits Slit repulsion, and facilitates Netrin attraction to achieve a common guidance purpose.

  3. NELL2 plays an important role in the regulation of neuronal differentiation via control of N-cadherin expression and cell aggregation.

  4. Nel interacts with a range of molecules through its different domains and exerts distinct functions.

  5. the NELL2 gene is trans-activated by E2 and contributes to mediating the survival promoting effects of E2 via intracellular signaling pathway of ERK

  6. NELL2 plays an important role as a novel suppressor in long-term potentiation in vivo in the mouse dentate gyrus

  7. NELL2 plays an important role in hippocampus-dependent spatial learning and that emotional learning does not depend critically on NELL2.

Human NEL-Like 2 (Chicken) (NELL2) interaction partners

  1. CSF NELL2 is a potential diagnostic biomarker for TBM.

  2. CpG islands in the NELL1 and NELL2 promoters are hypermethylated in renal cell carcinoma.NELL1 and NELL2 protein expression is downregulated in clear cell renal carcinoma.

  3. Cells overexpressing NELL2 increased their invasive ability and an enhancement of the effect was observed when NELL2 and E2F1 were coexpressed in MDA-MB231 cells.

Profil protéine NELL2

Profil protéine

The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis.

Gene names and symbols associated with NEL-Like 2 (Chicken) Protéines (NELL2)

  • neural EGFL like 2 L homeolog (nell2.L)
  • NEL-like 2 (Nell2)
  • neural EGFL like 2 (NELL2)
  • neural EGFL like 2 (Nell2)
  • neural EGFL like 2a (nell2a)
  • A330108N19Rik Protéine
  • mel91 Protéine
  • nel Protéine
  • nell2 Protéine
  • NRP2 Protéine
  • R75516 Protéine
  • wu:fj43h11 Protéine
  • zgc:158375 Protéine

Protein level used designations for NEL-Like 2 (Chicken) Protéines (NELL2)

NEL-like protein 2 , protein kinase C-binding protein NELL2 , nel-like 2 homolog , 93 kDa protein , Mr 93 K protein , protein NEL , NEL-related protein 2 , neural epidermal growth factor-like 2 , NEL-like 2

GENE ID SPECIES
380051 Xenopus laevis
54003 Mus musculus
417799 Gallus gallus
4753 Homo sapiens
524622 Bos taurus
81734 Rattus norvegicus
790930 Danio rerio
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